Reactome: A Curated Pathway Database

Version 40 Released

Posted on March 22nd, 2012, by robinhaw, under Reactome Release Announcement

The pathway Extracellular matrix organization is new and includes Activation of Matrix Metalloproteinases. Topics with new or revised events include Immune System (Regulation of complement cascade, Trafficking and processing of endosomal TLRSignaling by B cell receptor, and DAI mediated induction of type I IFNs), Metabolism of proteins, (Mitochondrial Protein Import), Signal transduction (Signaling by HippoSignaling by Notch), Circadian clock, and Gene Expression (Regulatory RNA Pathways). Sean Egan is our external author. DT Bradley G ButlerF DelaunayHS EarpT EndoL FraczekCA LeiferAM MisiorES MocarskiCM OverallFJ RauscherWA RoseM SudolY TomariJW Upton, and J Wienands are our external reviewers. We have created short Reactome tutorial videos that demonstrate the use of our navigation and analysis tools. New ones for this release are Pathway BrowserPathway Analysis, and Expression Analysis. Others will be added to the Reactome YouTube Channel as they become available. Our SBML export (available here) has been enriched with a wide variety of additional annotations, including SBO terms.  We have switched from using the layout extension to embedded SBGN for conveying pathway layout.

Reactome will be participating in Google Summer of Code 2012

Posted on March 16th, 2012, by robinhaw, under Grants and Funding, Reactome Announcement

The Genome Informatics group, organizing the joint efforts of Galaxy, GBrowse, Generic Model Organism Database (GMOD), JBrowse, Reactome, Wormbase, and PortEco will be participating in the Google Summer of Code 2012. Here is the complete list of the 180 accepted organizations, chosen by Google to take part in this exciting program. This is a great opportunity for undergraduate students to contribute to the work of these bioinformatics projects, to participate in open source development and to do work related to their academic pursuits during the summer. Students wishing to apply for Google Summer of Code will have the next 10 days to learn more about the accepted projects before student applications open on Monday, March 26, 2012 at 19:00 UTC.  More information about the project ideas and the GSoC program is available on the GMOD website. If you have any questions or queries, please feel free to send a post to the Genome Informatics Google Groups.