Visualize and interact with Reactome biological pathways
Merges pathway identifier mapping,
over-representation, and expression analysis
Designed to find pathways and network patterns related to cancer and other types of diseases
Information to browse the database and use its principal tools for data analysis
[March 15, 2024] Using WGCNA, GO and KEGG data analysis tools, He Y et al. in the January 2024 issue of BMC Medical Genomics, established a connection among the genes and pathways associated with type 2 diabetes (T2D) and ischemic stroke (IS) and identified GRN (granulin precursor) as the hub gene in T2D-related stroke. The functional enrichment analysis using Reactome analysis tool for GRN identified Neutrophil degranulation, Toll-like Receptor Cascades, DDX58/IFIH1-mediated induction of interferon-alpha/ beta, and NLR signaling pathways as shared biological processes in T2D and IS.
Human Pathways
Reactions
Proteins
Small Molecules
Drugs
Literature References
© 2024 Reactome