BioPAX pathway converted from "POM121 and NDC1 bind the Nup93 complex" in the Reactome database. POM121 and NDC1 bind the Nup93 complex POM121 and NDC1 bind the Nup93 complex This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 10030343 32 cytosol GO 0005829 Nup93 complex [cytosol] Nup93 complex Reactome DB_ID: 10030341 1 UniProt:Q66HC5 Nup93 Reactome http://www.reactome.org Rattus norvegicus NCBI Taxonomy 10116 UniProt Q66HC5 Chain Coordinates 1 EQUAL 819 EQUAL Reactome DB_ID: 10030339 1 UniProt:Q68FY1 Nup35 UniProt Q68FY1 1 EQUAL 326 EQUAL Reactome DB_ID: 10030335 1 UniProt:P37199 Nup155 UniProt P37199 1 EQUAL 1391 EQUAL Reactome DB_ID: 10030337 1 UniProt:D4A7R3 Nup205 UniProt D4A7R3 2 EQUAL 2012 EQUAL Reactome Database ID Release 82 10030343 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030343 Reactome R-RNO-9634166 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9634166.1 Reactome DB_ID: 10030345 16 UniProt:F1LRC6 Nup188 UniProt F1LRC6 2 EQUAL 1749 EQUAL Reactome DB_ID: 9935128 32 nuclear envelope GO 0005635 UniProt:Q6AXN4 Ndc1 UniProt Q6AXN4 1 EQUAL 674 EQUAL Reactome DB_ID: 10029946 1 POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] POM121:Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 9935122 16 UniProt:P52591 Pom121 UniProt P52591 1 EQUAL 1249 EQUAL Reactome DB_ID: 10029893 1 Nup107-160 complex:AHCTF1:Chromatin [cytosol] Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 9939164 16 UniProt:A0A0G2K160 Ahctf1 UniProt A0A0G2K160 1 EQUAL 2266 EQUAL Converted from EntitySet in Reactome Reactome DB_ID: 2537690 1 chromosome GO 0005694 Chromatin [chromosome] Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntity Reactome DB_ID: 9935162 32 Nup107-160 complex [cytosol] Nup107-160 complex Reactome DB_ID: 9935160 1 Ghost homologue of SEH1L-1 [cytosol] Ghost homologue of SEH1L-1 Reactome DB_ID: 9935150 1 UniProt:G3V6M8 Nup37 UniProt G3V6M8 1 EQUAL 326 EQUAL Reactome DB_ID: 9935158 1 UniProt:Q5XFW8 Sec13 UniProt Q5XFW8 2 EQUAL 322 EQUAL Reactome DB_ID: 9935140 1 UniProt:D3ZBL6 Nup160 UniProt D3ZBL6 1 EQUAL 1436 EQUAL Reactome DB_ID: 9935144 1 UniProt:Q4QQS8 Nup85 UniProt Q4QQS8 1 EQUAL 656 EQUAL Reactome DB_ID: 9935136 1 UniProt:D3Z8B2 Nup133 UniProt D3Z8B2 1 EQUAL 1156 EQUAL Reactome DB_ID: 9935154 1 UniProt:B0BNB5 Nup43 UniProt B0BNB5 1 EQUAL 380 EQUAL Reactome DB_ID: 9935146 1 UniProt:P49793 Nup98 UniProt P49793 1 EQUAL 880 EQUAL Reactome DB_ID: 9935132 1 UniProt:P52590 Nup107 UniProt P52590 1 EQUAL 925 EQUAL Reactome Database ID Release 82 9935162 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9935162 Reactome R-RNO-377883 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-377883.1 Reactome Database ID Release 82 10029893 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10029893 Reactome R-RNO-9615902 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9615902.1 Reactome Database ID Release 82 10029946 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10029946 Reactome R-RNO-9618374 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9618374.1 Reactome DB_ID: 10030347 1 Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin Reactome DB_ID: 10030343 32 Reactome DB_ID: 10030345 16 2 EQUAL 1749 EQUAL Reactome DB_ID: 9935128 32 1 EQUAL 674 EQUAL Reactome DB_ID: 10029946 1 Reactome Database ID Release 82 10030347 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030347 Reactome R-RNO-9634164 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9634164.1 Reactome Database ID Release 82 10030349 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030349 Reactome R-RNO-9634169 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9634169.1 From studies with Xenopus and human model systems, the transmembrane nucleoporins POM121 and NDC1 recruit the NUP93 complex to nascent nuclear pore complexes (NPCs) due to interaction with the NUP93 complex components NUP155 (Mitchell et al. 2010) and, potentially, NUP35 (Mansfield et al. 2006). This is consistent with order-of-assembly seen in live cell imaging (Dultz et al. 2008). 18316408 Pubmed 2008 Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells Dultz, Elisa Zanin, Esther Wurzenberger, Claudia Braun, Marion Rabut, Gwénaël Sironi, Lucia Ellenberg, Jan J. Cell Biol. 180:857-65 20974814 Pubmed 2010 Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane Mitchell, Jana M Mansfeld, Jörg Capitanio, Juliana Kutay, Ulrike Wozniak, Richard W J. Cell Biol. 191:505-21 16600873 Pubmed 2006 The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells Mansfeld, Jörg Güttinger, Stephan Hawryluk-Gara, Lisa A Panté, Nelly Mall, Moritz Galy, Vincent Haselmann, Uta Mühlhäusser, Petra Wozniak, Richard W Mattaj, Iain W Kutay, Ulrike Antonin, Wolfram Mol. Cell 22:93-103 inferred by electronic annotation IEA GO IEA