BioPAX pathway converted from "DNA polymerase epsilon binds at the origin" in the Reactome database.DNA polymerase epsilon binds at the originDNA polymerase epsilon binds at the originThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 100304271nucleoplasmGO0005654DNA polymerase epsilon [nucleoplasm]DNA polymerase epsilonReactome DB_ID: 100304171Ghost homologue of POLE2 [nucleoplasm]Ghost homologue of POLE2Reactomehttp://www.reactome.orgReactome DB_ID: 100304151UniProt:E1BIF0POLEBos taurusNCBI Taxonomy9913UniProtE1BIF0Chain Coordinates1EQUAL2286EQUALReactome DB_ID: 100304211UniProt:Q3SZN5UniProtQ3SZN52EQUAL147EQUALReactome DB_ID: 100304251UniProt:A6QQ14POLE4UniProtA6QQ142EQUAL117EQUALReactome Database ID Release 7510030427Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030427ReactomeR-BTA-684831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-68483.1Reactome DB_ID: 684191origin of replication [nucleoplasm]origin of replicationARSautonomously replicating sequenceoriginReactome DB_ID: 100304291DNA polymerase epsilon:origin complex [nucleoplasm]DNA polymerase epsilon:origin complexReactome DB_ID: 100304271Reactome DB_ID: 684191Reactome Database ID Release 7510030429Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030429ReactomeR-BTA-684851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-68485.1Reactome Database ID Release 7510030431Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10030431ReactomeR-BTA-689601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-68960.1At the beginning of this reaction, 1 molecule of 'origin of replication', and 1 molecule of 'DNA polymerase epsilon' are present. At the end of this reaction, 1 molecule of 'DNA polymerase epsilon:origin complex' is present.<br><br> <br>12045100Pubmed2002DNA replication in eukaryotic cells.Bell, SPDutta, AAnnu Rev Biochem 71:333-74inferred by electronic annotationIEAGOIEA