BioPAX pathway converted from "Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC" in the Reactome database.Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

Reactome DB_ID: 10198969

nucleoplasmGO0005654Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex [nucleoplasm]

Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex

Reactome DB_ID: 10194196

UniProt:F1Q7H6nxf1

Reactomehttp://www.reactome.orgDanio rerio

NCBI Taxonomy7955UniProtF1Q7H6

Chain Coordinates

EQUAL

619

EQUAL

Reactome DB_ID: 10191386

UniProt:A0A0R4IU36alyref

UniProtA0A0R4IU36

EQUAL

257

EQUAL

Reactome DB_ID: 111676

Mature Intronless transcript derived Histone mRNA [nucleoplasm]

Mature Intronless transcript derived Histone mRNA

Reactome DB_ID: 10195024

UniProt:A0A0R4IVR7slbp

UniProtA0A0R4IVR7

EQUAL

270

EQUAL

Reactome Database ID Release 7510198969Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10198969ReactomeR-DRE-159047

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-159047.1

Reactome DB_ID: 10198973

cytosolGO0005829Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex [cytosol]

Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex

Reactome DB_ID: 10194226

EQUAL

619

EQUAL

Reactome DB_ID: 10198971

EQUAL

270

EQUAL

Reactome DB_ID: 10194248

EQUAL

257

EQUAL

Reactome DB_ID: 113820

Mature intronless transcript derived Histone mRNA [cytosol]

Mature intronless transcript derived Histone mRNA

Reactome Database ID Release 7510198973Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10198973ReactomeR-DRE-159045

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-159045.1Reactome Database ID Release 7510198975Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10198975ReactomeR-DRE-159046

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-159046.1GO0006406

GO biological process

Once the transport complex is fully assembled the mature mRNA can be translocated from the nucleoplasm to the cytoplasm. The assembled complex starts at the nucleoplasmic basket, travels through the pore, and ends it journey at the cytoplasmic face of the nuclear pore complex.

23804756Pubmed2013Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteinsvon Moeller, HolgerLerner, RachelRicciardi, AdeleBasquin, ClaireMarzluff, William FConti, ElenaNucleic Acids Res. 41:7960-712017161Pubmed1991Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps.Harris, MEBohni, RSchneiderman, MHRamamurthy, LSchumperli, DMarzluff, William FMol Cell Biol 11:2416-24inferred by electronic annotationIEAGOIEA

ACTIVATION

Reactome Database ID Release 7510194267Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10194267

Reactome DB_ID: 10194188

nuclear envelopeGO0005635Nuclear Pore Complex (NPC) [nuclear envelope]

Nuclear Pore Complex (NPC)

Reactome DB_ID: 10194064

Nup62 Complex [nuclear envelope]

Nup62 Complex

Reactome DB_ID: 10194056

UniProt:A0A2R8QTE7nup62l

UniProtA0A2R8QTE7

EQUAL

522

EQUAL

Reactome DB_ID: 10194058

Ghost homologue of NUP54 [nuclear envelope]

Ghost homologue of NUP54

Reactome DB_ID: 10194062

UniProt:F1R2H0nup58

UniProtF1R2H0

EQUAL

599

EQUAL

Reactome Database ID Release 7510194064Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10194064ReactomeR-DRE-157712

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-157712.1

Reactome DB_ID: 10194134

UniProt:Q7SZC5ndc1

UniProtQ7SZC5

EQUAL

674

EQUAL

Reactome DB_ID: 10194186

Nup93 complex [nuclear envelope]

Nup93 complex

Reactome DB_ID: 10194172

UniProt:F1Q953nup155

UniProtF1Q953

EQUAL

1391

EQUAL

Reactome DB_ID: 10194184

UniProt:A0A2R8QTU4nup205

UniProtA0A2R8QTU4

EQUAL

2012

EQUAL

Reactome DB_ID: 10194176

UniProt:Q7ZU29dye

UniProtQ7ZU29

EQUAL

819

EQUAL

Reactome DB_ID: 10194180

UniProt:Q6P6X9nup35

UniProtQ6P6X9

EQUAL

326

EQUAL

Reactome Database ID Release 7510194186Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10194186ReactomeR-DRE-9634183

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634183.1

Reactome DB_ID: 10194084

UniProt:E7EXJ6nup188

UniProtE7EXJ6

EQUAL

1749

EQUAL

Reactome DB_ID: 10194114

UniProt:E7F981nup98

UniProtE7F981

EQUAL

863

EQUAL

Reactome DB_ID: 10194072

UniProt:F1QC46nup210

UniProtF1QC46

EQUAL

1887

EQUAL

Converted from EntitySet in Reactome

Reactome DB_ID: 10194130

POM121 [nuclear envelope]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityPOM121 [nuclear envelope]POM121C [nuclear envelope]nup214 [nuclear envelope]

UniProtF1R543UniProtE7F5M0

Reactome DB_ID: 10194110

UniProt:Q6TGU2seh1l

UniProtQ6TGU2

EQUAL

360

EQUAL

Reactome DB_ID: 10194106

UniProt:Q5RI09tprb

UniProtQ5RI09

EQUAL

2363

EQUAL

Reactome DB_ID: 10194168

Nup107-160 complex [cytosol]

Nup107-160 complex

Reactome DB_ID: 10194166

EQUAL

360

EQUAL

Reactome DB_ID: 10194138

UniProt:Q5RGI2nup107

UniProtQ5RGI2

EQUAL

925

EQUAL

Reactome DB_ID: 10194142

UniProt:F1QNV4nup133

UniProtF1QNV4

EQUAL

1156

EQUAL

Reactome DB_ID: 10194152

EQUAL

880

EQUAL

Reactome DB_ID: 10194150

UniProt:Q6DBY0nup85

UniProtQ6DBY0

EQUAL

656

EQUAL

Reactome DB_ID: 10194156

UniProt:J3JS14nup37

UniProtJ3JS14

EQUAL

326

EQUAL

Reactome DB_ID: 10194146

UniProt:A0A2R8Q4U1nup160

UniProtA0A2R8Q4U1

EQUAL

1436

EQUAL

Reactome DB_ID: 10194160

UniProt:Q5RFW3nup43

UniProtQ5RFW3

EQUAL

380

EQUAL

Reactome DB_ID: 10194164

UniProt:A0A2R8RKG2sec13

UniProtA0A2R8RKG2

EQUAL

322

EQUAL

Reactome Database ID Release 7510194168Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10194168ReactomeR-DRE-377883

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-377883.1

Reactome DB_ID: 10194068

UniProt:Q6NW98aaas

UniProtQ6NW98

EQUAL

546

EQUAL

Reactome DB_ID: 10194098

UniProt:A0A2R8QUY6

UniProtA0A2R8QUY6

EQUAL

741

EQUAL

Reactome DB_ID: 10194102

UniProt:Q7ZWF0rae1

UniProtQ7ZWF0

EQUAL

368

EQUAL

Reactome DB_ID: 10194076

UniProt:Q6P0U9nup42

UniProtQ6P0U9

EQUAL

423

EQUAL

Reactome DB_ID: 10194080

UniProt:A0A0R4IVZ0nup153

UniProtA0A0R4IVZ0

EQUAL

1475

EQUAL

Reactome DB_ID: 10194086

Ghost homologue of NUP214 [cytosol]

Ghost homologue of NUP214

Reactome DB_ID: 10194090

UniProt:A0A2R8QJ57ranbp2

UniProtA0A2R8QJ57

EQUAL

3224

EQUAL

Reactome DB_ID: 10194094

UniProt:F1R0E4nup50

UniProtF1R0E4

EQUAL

468

EQUAL

Reactome Database ID Release 7510194188Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10194188ReactomeR-DRE-157689

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-157689.1