BioPAX pathway converted from "SUMOylation of DAXX with SUMO1" in the Reactome database.SUMOylation of DAXX with SUMO1SUMOylation of DAXX with SUMO1This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 102455752nucleoplasmGO0005654SUMO1:C93-UBE2I [nucleoplasm]SUMO1:C93-UBE2IReactome DB_ID: 102455731UniProt:Q7SZR5Reactomehttp://www.reactome.orgDanio rerioNCBI Taxonomy7955UniProtQ7SZR5Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 97 and 93 (in Homo sapiens)97EQUALS-(glycyl)-L-cysteine (Cys-Gly)ChEBI23511modificationChain Coordinates2EQUAL97EQUALConverted from EntitySet in ReactomeReactome DB_ID: 102455701Homologues of SUMO1-C93-UBE2I [nucleoplasm]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntitySUMO1-C93-UBE2I [nucleoplasm]SUMO1-C93-UBE2I [nucleoplasm]UniProtQ9DDJ0UniProtX1WFY0Reactome Database ID Release 7010245575Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10245575ReactomeR-DRE-29937831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2993783.1Reactome DB_ID: 102462181UniProt:Q1LUU4UniProtQ1LUU41EQUAL740EQUALReactome DB_ID: 1024971812SUMO1:DAXX [nucleoplasm]2SUMO1:DAXXReactome DB_ID: 102497161Inter-chain Crosslink via sumoylated lysine at 630 and 97 (in Homo sapiens)630EQUALsumoylated lysineChEBI24411modificationInter-chain Crosslink via sumoylated lysine at 631 and 97 (in Homo sapiens)631EQUAL1EQUAL740EQUALReactome DB_ID: 102497122Inter-chain Crosslink via sumoylated lysine at 97 and 630 (in Homo sapiens)97EQUALChEBI30777modification2EQUAL97EQUALReactome Database ID Release 7010249718Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10249718ReactomeR-DRE-40860321Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-4086032.1Converted from EntitySet in ReactomeReactome DB_ID: 102455622Homologues of UBE2I [nucleoplasm]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityUBE2I [nucleoplasm]UBE2I [nucleoplasm]PHYSIOL-LEFT-TO-RIGHTACTIVATIONReactome DB_ID: 10245575GO0019789GO molecular functionReactome Database ID Release 7010246526Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10246526Reactome Database ID Release 7010249720Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10249720ReactomeR-DRE-40859921Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-4085992.1DAXX is SUMOylated at lysine-630 and lysine-631 with SUMO1 (Jang et al. 2002, Lalioti et al. 2002, Lin et al. 2006). SUMOylation of DAXX does not prevent it from localizing to PML oncogenic domains.12150977Pubmed2002Modification of Daxx by small ubiquitin-related modifier-1Jang, Moon-SunRyu, Seung-WookKim, EunheeBiochem. Biophys. Res. Commun. 295:495-50017081986Pubmed2006Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factorsLin, Ding-YenHuang, Yen-SungJeng, Jen-ChongKuo, Hong-YiChang, Che-ChangChao, Ting-TingHo, Chun-ChenChen, Yun-ChingLin, Tong-PingFang, Hsin-IHung, Chih-ChangSuen, Ching-ShuHwang, Ming-JingChang, Kun-SangMaul, Gerd GShih, Hsiu-MingMol. Cell 24:341-5411842083Pubmed2002The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1Lalioti, Vassiliki SVergarajauregui, SilviaPulido, DiegoSandoval, Ignacio VJ. Biol. Chem. 277:19783-91inferred by electronic annotationIEAGOIEA