BioPAX pathway converted from "SFTPB binds itself" in the Reactome database.
SFTPB binds itself
SFTPB binds itself
SFTPB dimerises
This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>
Reactome DB_ID: 10327005
2
multivesicular body lumen
GO
0097486
UniProt:A0A287B0B8
SFTPB
Reactome
http://www.reactome.org
Sus scrofa
NCBI Taxonomy
9823
UniProt
A0A287B0B8
Chain Coordinates
201
EQUAL
279
EQUAL
Reactome DB_ID: 10327032
1
SFTPB dimer [multivesicular body lumen]
SFTPB dimer
Reactome DB_ID: 10327005
2
201
EQUAL
279
EQUAL
Reactome Database ID Release 83
10327032
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10327032
Reactome
R-SSC-6791014
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SSC-6791014.1
Reactome Database ID Release 83
10332324
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10332324
Reactome
R-SSC-6791016
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SSC-6791016.1
After pro-SFTPB is cleaved, the resultant mature peptide SFTPB (chain 201-279) forms a dimeric, disulfide linked protein (Johansson et al. 1992) and is trafficked to lamellar bodies.
1568474
Pubmed
1992
Human surfactant polypeptide SP-B. Disulfide bridges, C-terminal end, and peptide analysis of the airway form
Johansson, J
Jörnvall, H
Curstedt, T
FEBS Lett. 301:165-7
inferred by electronic annotation
IEA
GO
IEA