BioPAX pathway converted from "YAP1 binds ZO-2 (TJP2)" in the Reactome database. YAP1 binds ZO-2 (TJP2) YAP1 binds ZO-2 (TJP2) This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 10410539 1 cytosol GO 0005829 UniProt:A0A2R8QB05 Reactome http://www.reactome.org Danio rerio NCBI Taxonomy 7955 UniProt A0A2R8QB05 Chain Coordinates 1 EQUAL 1190 EQUAL Reactome DB_ID: 10399972 1 UniProt:Q1L8J7 yap1 UniProt Q1L8J7 1 EQUAL 504 EQUAL Reactome DB_ID: 10410541 1 YAP1:TJP2 [cytosol] YAP1:TJP2 Reactome DB_ID: 10410539 1 1 EQUAL 1190 EQUAL Reactome DB_ID: 10399972 1 1 EQUAL 504 EQUAL Reactome Database ID Release 82 10410541 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410541 Reactome R-DRE-2064400 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064400.1 Reactome Database ID Release 82 10410563 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410563 Reactome R-DRE-2064421 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064421.1 Cytosolic ZO-2 (TJP2) binds YAP1 to form a complex (Oka et al. 2010). The phosphorylation state of the YAP1 protein involved in this interaction has not been determined experimentally; it is inferred to be unphosphorylated. 20868367 Pubmed 2010 Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling Oka, T Remue, E Meerschaert, K Vanloo, B Boucherie, C Gfeller, D Bader, GD Sidhu, SS Vandekerckhove, J Gettemans, J Sudol, M Biochem J 432:461-72 inferred by electronic annotation IEA GO IEA