BioPAX pathway converted from "Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC" in the Reactome database.Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

Reactome DB_ID: 10497542

nucleoplasmGO0005654Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex [nucleoplasm]

Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex

Reactome DB_ID: 10493941

UniProt:Q9V3E7Ref1

Reactomehttp://www.reactome.orgDrosophila melanogaster

NCBI Taxonomy7227UniProtQ9V3E7

Chain Coordinates

EQUAL

257

EQUAL

Reactome DB_ID: 10496760

UniProt:Q9U1H9sbr

UniProtQ9U1H9

EQUAL

619

EQUAL

Reactome DB_ID: 10497493

UniProt:Q9VAN6Slbp

UniProtQ9VAN6

EQUAL

270

EQUAL

Reactome DB_ID: 111676

Mature Intronless transcript derived Histone mRNA [nucleoplasm]

Mature Intronless transcript derived Histone mRNA

Reactome Database ID Release 7510497542Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10497542ReactomeR-DME-159047

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-159047.1

Reactome DB_ID: 10500294

cytosolGO0005829Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex [cytosol]

Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex

Reactome DB_ID: 10496801

EQUAL

619

EQUAL

Reactome DB_ID: 10496827

EQUAL

257

EQUAL

Reactome DB_ID: 10500292

EQUAL

270

EQUAL

Reactome DB_ID: 113820

Mature intronless transcript derived Histone mRNA [cytosol]

Mature intronless transcript derived Histone mRNA

Reactome Database ID Release 7510500294Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10500294ReactomeR-DME-159045

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-159045.1Reactome Database ID Release 7510500296Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10500296ReactomeR-DME-159046

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-159046.1GO0006406

GO biological process

Once the transport complex is fully assembled the mature mRNA can be translocated from the nucleoplasm to the cytoplasm. The assembled complex starts at the nucleoplasmic basket, travels through the pore, and ends it journey at the cytoplasmic face of the nuclear pore complex.

23804756Pubmed2013Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteinsvon Moeller, HolgerLerner, RachelRicciardi, AdeleBasquin, ClaireMarzluff, William FConti, ElenaNucleic Acids Res. 41:7960-712017161Pubmed1991Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps.Harris, MEBohni, RSchneiderman, MHRamamurthy, LSchumperli, DMarzluff, William FMol Cell Biol 11:2416-24inferred by electronic annotationIEAGOIEA

ACTIVATION

Reactome Database ID Release 7510496847Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10496847

Reactome DB_ID: 10496750

nuclear envelopeGO0005635Nuclear Pore Complex (NPC) [nuclear envelope]

Nuclear Pore Complex (NPC)

Reactome DB_ID: 10496624

Ghost homologue of NUP188 [nuclear envelope]

Ghost homologue of NUP188

Reactome DB_ID: 10496648

UniProt:Q9GYU8mbo

UniProtQ9GYU8

EQUAL

741

EQUAL

Converted from EntitySet in Reactome

Reactome DB_ID: 10496636

Homologues of NUP214 [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityNup214 [cytosol]Dmel\CG14712 [cytosol]

UniProtQ9W1X4UniProtQ9VGL0

Reactome DB_ID: 10496726

Nup107-160 complex [cytosol]

Nup107-160 complex

Reactome DB_ID: 10496707

UniProt:Q9VCH5Nup98-96

UniProtQ9VCH5

EQUAL

880

EQUAL

Reactome DB_ID: 10496705

UniProt:A1YK02Nup75

UniProtA1YK02

EQUAL

656

EQUAL

Reactome DB_ID: 10496690

UniProt:Q9V466Nup107

UniProtQ9V466

EQUAL

925

EQUAL

Reactome DB_ID: 10496695

UniProt:Q9VCW3Nup133

UniProtQ9VCW3

EQUAL

1156

EQUAL

Reactome DB_ID: 10496717

UniProt:Q9VE85Nup43

UniProtQ9VE85

EQUAL

380

EQUAL

Reactome DB_ID: 10496712

UniProt:Q9VBU8Nup37

UniProtQ9VBU8

EQUAL

326

EQUAL

Reactome DB_ID: 10496700

UniProt:Q9VKJ3Nup160

UniProtQ9VKJ3

EQUAL

1436

EQUAL

Reactome DB_ID: 10496722

UniProt:Q9V3J4Sec13

UniProtQ9V3J4

EQUAL

322

EQUAL

Reactome DB_ID: 10496724

UniProt:Q7K2X8Nup44A

UniProtQ7K2X8

EQUAL

360

EQUAL

Reactome Database ID Release 7510496726Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10496726ReactomeR-DME-377883

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-377883.1

Reactome DB_ID: 10496638

Ghost homologue of RANBP2 [cytosol]

Ghost homologue of RANBP2

Reactome DB_ID: 10496668

EQUAL

863

EQUAL

Reactome DB_ID: 10496748

Nup93 complex [nuclear envelope]

Nup93 complex

Reactome DB_ID: 10496736

UniProt:Q9VFE7Nup93-2

UniProtQ9VFE7

EQUAL

819

EQUAL

Reactome DB_ID: 10496741

UniProt:Q9VWS2Nup35

UniProtQ9VWS2

EQUAL

326

EQUAL

Reactome DB_ID: 10496731

UniProt:Q9V463Nup154

UniProtQ9V463

EQUAL

1391

EQUAL

Reactome DB_ID: 10496746

UniProt:Q8IQV9Nup205

UniProtQ8IQV9

EQUAL

2012

EQUAL

Reactome Database ID Release 7510496748Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10496748ReactomeR-DME-9634183

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-9634183.1

Reactome DB_ID: 10496643

UniProt:Q7K0D8Nup50

UniProtQ7K0D8

EQUAL

468

EQUAL

Converted from EntitySet in Reactome

Reactome DB_ID: 10496680

POM121 [nuclear envelope]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityNup214 [nuclear envelope]Dmel\CG14712 [nuclear envelope]Nup214 [nuclear envelope]

Reactome DB_ID: 10496612

UniProt:A1Z6H7Gp210

UniProtA1Z6H7

EQUAL

1887

EQUAL

Reactome DB_ID: 10496602

Nup62 Complex [nuclear envelope]

Nup62 Complex

Reactome DB_ID: 10496595

UniProt:Q9V6B9Nup54

UniProtQ9V6B9

EQUAL

507

EQUAL

Reactome DB_ID: 10496600

UniProt:Q9VDV3Nup58

UniProtQ9VDV3

EQUAL

599

EQUAL

Reactome DB_ID: 10496590

UniProt:Q7JXF5Nup62

UniProtQ7JXF5

EQUAL

522

EQUAL

Reactome Database ID Release 7510496602Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10496602ReactomeR-DME-157712

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-157712.1

Reactome DB_ID: 10496607

UniProt:Q9W351Aladin

UniProtQ9W351

EQUAL

546

EQUAL

Reactome DB_ID: 10496622

UniProt:Q9VXE6Nup153

UniProtQ9VXE6

EQUAL

1475

EQUAL

Reactome DB_ID: 10496658

UniProt:A1Z8P9Mtor

UniProtA1Z8P9

EQUAL

2363

EQUAL

Reactome DB_ID: 10496653

UniProt:Q9W2E7Rae1

UniProtQ9W2E7

EQUAL

368

EQUAL

Reactome DB_ID: 10496617

UniProt:Q9I7N3Dmel\CG18789

UniProtQ9I7N3

EQUAL

423

EQUAL

Reactome DB_ID: 10496685

UniProt:Q9VCG4Ndc1

UniProtQ9VCG4

EQUAL

674

EQUAL

Reactome DB_ID: 10496663

EQUAL

360

EQUAL

Reactome Database ID Release 7510496750Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10496750ReactomeR-DME-157689

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-157689.1