BioPAX pathway converted from "DHX9 binds DNA" in the Reactome database.DHX9 binds DNADHX9 binds DNAThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 31348611cytosolGO0005829Unmethylated CpG DNA [cytosol]Unmethylated CpG DNAReactomehttp://www.reactome.orgReactome DB_ID: 106134201UniProt:Q22307rha-1Caenorhabditis elegansNCBI Taxonomy6239UniProtQ22307Chain Coordinates1EQUAL1270EQUALReactome DB_ID: 106134221DHX9:CpG [cytosol]DHX9:CpGReactome DB_ID: 31348611Reactome DB_ID: 1061342011EQUAL1270EQUALReactome Database ID Release 7510613422Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10613422ReactomeR-CEL-31349601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CEL-3134960.1Reactome Database ID Release 7510613424Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10613424ReactomeR-CEL-31349541Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CEL-3134954.1DHX9 binds CpG-B in human plasmacytoid dendritic cells (pDC). The DUF domain of DHX9 was shown to be essential for binding CpG-B [Kim T et al 2010].20696886Pubmed2010Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cellsKim, TaeilPazhoor, ShwethaBao, MushengZhang, ZhiqiangHanabuchi, ShinoFacchinetti, ValeriaBover, LauraPlumas, JoelChaperot, LaurenceQin, JLiu, Yong-JunProc. Natl. Acad. Sci. U.S.A. 107:15181-6inferred by electronic annotationIEAGOIEA