BioPAX pathway converted from "Enzyme-bound ATP is released" in the Reactome database. Enzyme-bound ATP is released Enzyme-bound ATP is released This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 163953 3 mitochondrial intermembrane space GO 0005758 hydron [ChEBI:15378] hydron Reactome http://www.reactome.org ChEBI 15378 Reactome DB_ID: 10680328 1 mitochondrial inner membrane GO 0005743 ATPase:ATP [mitochondrial inner membrane] ATPase:ATP Reactome DB_ID: 113593 1 mitochondrial matrix GO 0005759 ATP(4-) [ChEBI:30616] ATP(4-) Adenosine 5'-triphosphate atp ATP ChEBI 30616 Reactome DB_ID: 10680324 1 F1Fo ATP synthase [mitochondrial inner membrane] F1Fo ATP synthase Reactome DB_ID: 10680315 1 UniProt:Q24439 ATPsynO Drosophila melanogaster NCBI Taxonomy 7227 UniProt Q24439 Chain Coordinates 24 EQUAL 213 EQUAL Reactome DB_ID: 10680310 1 ATPase CF(0) [mitochondrial inner membrane] ATPase CF(0) Reactome DB_ID: 10680272 1 UniProt:Q24251 ATPsynD UniProt Q24251 2 EQUAL 161 EQUAL Reactome DB_ID: 10680282 1 UniProt:Q9W141 ATPsynF UniProt Q9W141 2 EQUAL 94 EQUAL Reactome DB_ID: 10680299 1 UniProt:Q6NN09 ATPsynC UniProt Q6NN09 62 EQUAL 136 EQUAL Reactome DB_ID: 10680289 1 Ghost homologue of MT-ATP8 [mitochondrial inner membrane] Ghost homologue of MT-ATP8 Reactome DB_ID: 10680294 1 UniProt:Q24407 ATPsynCF6 UniProt Q24407 33 EQUAL 108 EQUAL Reactome DB_ID: 10680306 1 mitochondrial outer membrane GO 0005741 67 EQUAL 141 EQUAL Reactome DB_ID: 10680267 1 UniProt:P00850 mt:ATPase6 UniProt P00850 1 EQUAL 226 EQUAL Reactome DB_ID: 10680304 1 UniProt:Q94516 ATPsynB UniProt Q94516 43 EQUAL 256 EQUAL Reactome DB_ID: 10680287 1 UniProt:Q9VKM3 ATPsynG UniProt Q9VKM3 2 EQUAL 103 EQUAL Reactome DB_ID: 10680277 1 UniProt:O77134 ATPsynE UniProt O77134 2 EQUAL 69 EQUAL Reactome DB_ID: 10680308 1 68 EQUAL 142 EQUAL Reactome Database ID Release 83 10680310 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680310 Reactome R-DME-74185 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-74185.1 Reactome DB_ID: 10680262 1 ATPase CF(1) [mitochondrial matrix] ATPase CF(1) Reactome DB_ID: 10680245 3 UniProt:Q05825 UniProt Q05825 48 EQUAL 529 EQUAL Reactome DB_ID: 10680250 1 UniProt:O01666 ATPsyngamma UniProt O01666 26 EQUAL 298 EQUAL Reactome DB_ID: 10680240 3 UniProt:P35381 UniProt P35381 44 EQUAL 553 EQUAL Reactome DB_ID: 10680255 1 UniProt:Q9W2X6 ATPsyndelta UniProt Q9W2X6 23 EQUAL 168 EQUAL Reactome DB_ID: 10680260 1 UniProt:Q9VXN2 sun UniProt Q9VXN2 2 EQUAL 51 EQUAL Reactome Database ID Release 83 10680262 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680262 Reactome R-DME-74184 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-74184.1 Reactome DB_ID: 10680322 1 ATP5S tetramer [mitochondrial inner membrane] ATP5S tetramer Reactome DB_ID: 10680320 4 UniProt:A1ZAA9 ATPW UniProt A1ZAA9 41 EQUAL 215 EQUAL Reactome Database ID Release 83 10680322 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680322 Reactome R-DME-5252095 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-5252095.1 Reactome Database ID Release 83 10680324 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680324 Reactome R-DME-74186 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-74186.1 Reactome Database ID Release 83 10680328 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680328 Reactome R-DME-164835 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-164835.1 Reactome DB_ID: 113593 1 Reactome DB_ID: 113529 3 Reactome DB_ID: 10680324 1 PHYSIOL-LEFT-TO-RIGHT ACTIVATION Reactome DB_ID: 10680328 GO 0015078 GO molecular function Reactome Database ID Release 83 10680332 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680332 Reactome Database ID Release 83 10680334 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10680334 Reactome R-DME-164834 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-164834.1 GO 0042776 GO biological process In the last step, the beta subunit is converted to the open form and ATP is released. Passage of protons through the Fo part causes a ring of approximately 10 subunits to rotate. This rotation in turn drives the rotation of the gamma subunits, which forms part of one of the stalks. The gamma subunit moves between the three beta subunits which are held in place by the second stalk which can be regarded as a stator. The polypeptide called OSCP connects the stator stalk to the assembly of alpha and beta subunits. It is this step that is coupled to proton translocation as energy is required to break the strong bond between ATP and the protein. 4517936 Pubmed 1973 A new concept for energy coupling in oxidative phosphorylation based on a Boyer, PD Cross, RL Momsen, W Proc Natl Acad Sci U S A 70:2837-9 inferred by electronic annotation IEA GO IEA