BioPAX pathway converted from "Ca permeable AMPA receptor ligand binding" in the Reactome database. Ca permeable AMPA receptor ligand binding Ca permeable AMPA receptor ligand binding This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 210382 1 extracellular region GO 0005576 L-glutamate(1-) [ChEBI:29985] L-glutamate(1-) C5H8NO4 WHUUTDBJXJRKMK-VKHMYHEASA-M (2S)-2-ammoniopentanedioate 146.12136 L-glutamate hydrogen L-glutamate InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1 L-glutamic acid, ion(1-) [NH3+][C@@H](CCC([O-])=O)C([O-])=O L-glutamic acid monoanion Reactome http://www.reactome.org ChEBI 29985 Converted from EntitySet in Reactome Reactome DB_ID: 10683557 1 plasma membrane GO 0005886 Ca permeable AMPA receptors [plasma membrane] Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntity Reactome DB_ID: 10683559 1 Ca permeable AMPA receptor ligand complex [plasma membrane] Ca permeable AMPA receptor ligand complex Reactome DB_ID: 210382 1 Converted from EntitySet in Reactome Reactome DB_ID: 10683557 1 Drosophila melanogaster NCBI Taxonomy 7227 Reactome Database ID Release 82 10683559 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10683559 Reactome R-DME-420976 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-420976.1 Reactome Database ID Release 82 10684330 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10684330 Reactome R-DME-420977 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-420977.1 AMPA receptors bind glutamate, released in the synaptic cleft by the presynaptic cell, in the ligand binding region in the N terminal domain. 14567697 Pubmed 2003 Channel-opening kinetics of GluR2Q(flip) AMPA receptor: a laser-pulse photolysis study Li, G Pei, W Niu, L Biochemistry 42:12358-66 19144831 Pubmed 2009 Agonist occupancy is essential for forward trafficking of AMPA receptors Coleman, SK Möykkynen, T Jouppila, A Koskelainen, S Rivera, C Korpi, ER Keinänen, K J Neurosci 29:303-12 inferred by electronic annotation IEA GO IEA