BioPAX pathway converted from "Adenylate Kinase 3 is a GTP-AMP phosphotransferase" in the Reactome database.

2.7.4.10

Adenylate Kinase 3 is a GTP-AMP phosphotransferase

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

Reactome DB_ID: 113573

mitochondrial matrixGO0005759

GTP [ChEBI:15996]

GTP

Guanosine 5'-triphosphate

Reactomehttp://www.reactome.orgChEBI15996

Reactome DB_ID: 159448

adenosine 5'-monophosphate [ChEBI:16027]

adenosine 5'-monophosphate

ChEBI16027

Reactome DB_ID: 113581

ADP(3-) [ChEBI:456216]

ADP(3-)

ADP trianion5'-O-[(phosphonatooxy)phosphinato]adenosineADP

ChEBI456216

Reactome DB_ID: 113525

GDP [ChEBI:17552]

GDP

Guanosine 5'-diphosphateGuanosine diphosphate

ChEBI17552PHYSIOL-LEFT-TO-RIGHT

ACTIVATION

Reactome DB_ID: 10738731

UniProt:P26364ADK2

Saccharomyces cerevisiae

NCBI Taxonomy4932UniProtP26364

Chain Coordinates

EQUAL

227

EQUAL

GO0046899

GO molecular function

Reactome Database ID Release 7510738732Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10738732Reactome Database ID Release 7510738734Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10738734ReactomeR-SCE-1008248

Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-1008248.1GTP-AMP phosphotransferase, also called Adenylate kinase 3 catalyzes phosphate transfer from GTP to AMP (EC 2.7.4.10). A crystal structure is available (Choe et al. 2005).

218813Pubmed1979Mitochondrial GTP-AMP phosphotransferase. 2. Kinetic and equilibrium dialysis studiesTomasselli, AGNoda, LHEur J Biochem 93:263-7http://www.thesgc.org/structures/structure_description/1ZD8/AK3L1 - Human Adenylate Kinase 3-Like 1Choe, JAtanassova, AArrowsmith, CHEdwards, AMSundstrom, MBochkarev, APark, Hinferred by electronic annotationIEAGOIEA