BioPAX pathway converted from "DNA polymerase epsilon binds at the origin" in the Reactome database.DNA polymerase epsilon binds at the originDNA polymerase epsilon binds at the originThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 107550301nucleoplasmGO0005654DNA polymerase epsilon [nucleoplasm]DNA polymerase epsilonReactome DB_ID: 107550161UniProt:C6KTD8Reactomehttp://www.reactome.orgPlasmodium falciparumNCBI Taxonomy5833UniProtC6KTD8Chain Coordinates1EQUAL2286EQUALReactome DB_ID: 107550281Ghost homologue of POLE4 [nucleoplasm]Ghost homologue of POLE4Reactome DB_ID: 107550261UniProt:Q8IEN4UniProtQ8IEN42EQUAL147EQUALReactome DB_ID: 107550211UniProt:Q8I579UniProtQ8I5791EQUAL527EQUALReactome Database ID Release 7510755030Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10755030ReactomeR-PFA-684831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-PFA-68483.1Reactome DB_ID: 684191origin of replication [nucleoplasm]origin of replicationARSautonomously replicating sequenceoriginReactome DB_ID: 107550321DNA polymerase epsilon:origin complex [nucleoplasm]DNA polymerase epsilon:origin complexReactome DB_ID: 107550301Reactome DB_ID: 684191Reactome Database ID Release 7510755032Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10755032ReactomeR-PFA-684851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-PFA-68485.1Reactome Database ID Release 7510755386Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10755386ReactomeR-PFA-689601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-PFA-68960.1At the beginning of this reaction, 1 molecule of 'origin of replication', and 1 molecule of 'DNA polymerase epsilon' are present. At the end of this reaction, 1 molecule of 'DNA polymerase epsilon:origin complex' is present.<br><br> <br>12045100Pubmed2002DNA replication in eukaryotic cells.Bell, SPDutta, AAnnu Rev Biochem 71:333-74inferred by electronic annotationIEAGOIEA