BioPAX pathway converted from "Mitochondrial recruitment of Drp1" in the Reactome database. Mitochondrial recruitment of Drp1 Mitochondrial recruitment of Drp1 This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 10900713 1 cytosol GO 0005829 UniProt:P54861 Reactome http://www.reactome.org Saccharomyces cerevisiae NCBI Taxonomy 4932 UniProt P54861 Chain Coordinates 1 EQUAL 736 EQUAL Reactome DB_ID: 10900715 1 mitochondrial outer membrane GO 0005741 1 EQUAL 736 EQUAL Reactome Database ID Release 82 10900717 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900717 Reactome R-SCE-351948 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-351948.1 Adenoviral expression of the BAP31 cleavage product, p20 causes early release of Ca2+ from the ER, concomitant uptake of Ca2+ into mitochondria, and recruitment of Drp1 to the mitochondria (Breckenridge et al., 2003). Drp1 mediates scission of the outer mitochondrial membrane, resulting in dramatic fragmentation and fission of the mitochondrial network. 12668660 Pubmed 2003 Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol Breckenridge, DG Stojanovic, M Marcellus, RC Shore, GC J Cell Biol 160:1115-27 inferred by electronic annotation IEA GO IEA ACTIVATION Reactome Database ID Release 82 10900718 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900718 Reactome DB_ID: 10900690 endoplasmic reticulum membrane GO 0005789 UniProt:Q07451 YET3 UniProt Q07451 2 EQUAL 164 EQUAL