BioPAX pathway converted from "Mad1 binds kinetochore" in the Reactome database.Mad1 binds kinetochoreMad1 binds kinetochoreThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 99430881cytosolGO0005829Kinetochore [cytosol]KinetochoreReactome DB_ID: 99430441UniProt:J9NX78BUB1Reactomehttp://www.reactome.orgCanis familiarisNCBI Taxonomy9615UniProtJ9NX78Chain Coordinates1EQUAL1085EQUALReactome DB_ID: 99427921UniProt:F1PD03KIF2CUniProtF1PD031EQUAL725EQUALReactome DB_ID: 99427841UniProt:J9P9X3KIF2AUniProtJ9P9X31EQUAL706EQUALReactome DB_ID: 99428861UniProt:E2QZR1DOCK2UniProtE2QZR11EQUAL605EQUALReactome DB_ID: 99430241UniProt:E2RGS2CDC20UniProtE2RGS21EQUAL499EQUALReactome DB_ID: 99428201UniProt:J9JHT3SKA2UniProtJ9JHT31EQUAL121EQUALReactome DB_ID: 99428901UniProt:E2RSW0CKAP5UniProtE2RSW01EQUAL2032EQUALReactome DB_ID: 99428921Ghost homologue of B9D2 [cytosol]Ghost homologue of B9D2Reactome DB_ID: 99428961UniProt:E2QWB0CLIP1UniProtE2QWB01EQUAL1438EQUALReactome DB_ID: 99430521UniProt:E2QRV2TAOK1UniProtE2QRV21EQUAL1001EQUALReactome DB_ID: 99427501UniProt:F6XU88INCENPUniProtF6XU881EQUAL918EQUALReactome DB_ID: 99429541CCAN network [cytosol]CCAN networkReactome DB_ID: 99429201Ghost homologue of CENPT [cytosol]Ghost homologue of CENPTReactome DB_ID: 99429121UniProt:E2RRU1CENPMUniProtE2RRU11EQUAL180EQUALReactome DB_ID: 99429161UniProt:F1PCB7CENPNUniProtF1PCB71EQUAL339EQUALReactome DB_ID: 99429081UniProt:E2RAU1CENPLUniProtE2RAU11EQUAL344EQUALReactome DB_ID: 99429521CENP-(H,I, K) complex [cytosol]CENP-(H,I, K) complexReactome DB_ID: 99429441UniProt:E2R8X4CENPHUniProtE2R8X41EQUAL247EQUALReactome DB_ID: 99429501UniProt:E2QWG9CENPKUniProtE2QWG91EQUAL269EQUALReactome DB_ID: 99429461Ghost homologue of CENPI [cytosol]Ghost homologue of CENPIReactome Database ID Release 759942952Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942952ReactomeR-CFA-3778841Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377884.1Reactome DB_ID: 99429181Ghost homologue of APITD1 [cytosol]Ghost homologue of APITD1Reactome DB_ID: 99429041UniProt:F1PXT1UBA6UniProtF1PXT11EQUAL943EQUALReactome DB_ID: 99429401CENP-O complex [cytosol]CENP-O complexReactome DB_ID: 99429281UniProt:E2RPH9CENPPUniProtE2RPH91EQUAL288EQUALReactome DB_ID: 99429361UniProt:F1Q0R8CENPUUniProtF1Q0R81EQUAL418EQUALReactome DB_ID: 99429381Ghost homologue of ITGB3BP [cytosol]Ghost homologue of ITGB3BPReactome DB_ID: 99429241UniProt:J9P8H8CENPOUniProtJ9P8H81EQUAL300EQUALReactome DB_ID: 99429321UniProt:E2RKY1CENPQUniProtE2RKY11EQUAL268EQUALReactome Database ID Release 759942940Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942940ReactomeR-CFA-3778861Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377886.1Reactome Database ID Release 759942954Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942954ReactomeR-CFA-3777381Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377738.1Reactome DB_ID: 99430481UniProt:J9P3F5ERCC6LUniProtJ9P3F51EQUAL1250EQUALReactome DB_ID: 99429961KMN network [cytosol]KMN networkReactome DB_ID: 99429941NDC80 complex [cytosol]NDC80 complexReactome DB_ID: 99429881UniProt:E2R9Q9SPC24UniProtE2R9Q91EQUAL197EQUALReactome DB_ID: 99429921UniProt:E2QYQ7SPC25UniProtE2QYQ71EQUAL224EQUALReactome DB_ID: 99429801UniProt:E2RIY7NDC80UniProtE2RIY71EQUAL642EQUALReactome DB_ID: 99429841UniProt:E2RJ16NUF2UniProtE2RJ161EQUAL464EQUALReactome Database ID Release 759942994Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942994ReactomeR-CFA-3754441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-375444.1Reactome DB_ID: 99429581UniProt:E2RC04KNL1UniProtE2RC041EQUAL2342EQUALReactome DB_ID: 99429761Mis12 complex [cytosol]Mis12 complexReactome DB_ID: 99429621UniProt:F6UTX5DSN1UniProtF6UTX51EQUAL356EQUALReactome DB_ID: 99429661UniProt:E2RIE6MIS12UniProtE2RIE61EQUAL205EQUALReactome DB_ID: 99429741UniProt:F1PDW9SLC25A44UniProtF1PDW92EQUAL205EQUALReactome DB_ID: 99429701UniProt:E2RTF4NSL1UniProtE2RTF41EQUAL281EQUALReactome Database ID Release 759942976Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942976ReactomeR-CFA-3754411Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-375441.1Reactome Database ID Release 759942996Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942996ReactomeR-CFA-3777451Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377745.1Reactome DB_ID: 99427641UniProt:F1PD21CLASP1UniProtF1PD211EQUAL1538EQUALReactome DB_ID: 99427461UniProt:F1PAV9MAD1L1UniProtF1PAV91EQUAL718EQUALReactome DB_ID: 99427961UniProt:E2R5A9UniProtE2R5A91EQUAL346EQUALReactome DB_ID: 99371561UniProt:E2RLE2RPS27UniProtE2RLE22EQUAL84EQUALReactome DB_ID: 99428121UniProt:J9PB57SGO2UniProtJ9PB571EQUAL1265EQUALReactome DB_ID: 99428161UniProt:E2RI68SKA1UniProtE2RI682EQUAL255EQUALReactome DB_ID: 99428081UniProt:F6XSF4SGO1UniProtF6XSF41EQUAL561EQUALReactome DB_ID: 99427801UniProt:E2RAH7KIF18AUniProtE2RAH71EQUAL898EQUALReactome DB_ID: 99427581UniProt:E2R200CENPEUniProtE2R2001EQUAL2698EQUALReactome DB_ID: 99428681PP2A [cytosol]PP2AConverted from EntitySet in ReactomeReactome DB_ID: 99428661PP2A-catalytic subunit C [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityConverted from EntitySet in ReactomeReactome DB_ID: 99428501PP2A regulatory subunit B56 [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityConverted from EntitySet in ReactomeReactome DB_ID: 99428601PP2A-subunit A [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityReactome Database ID Release 759942868Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9942868ReactomeR-CFA-1962061Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-196206.1Reactome DB_ID: 99428761UniProt:J9P0Q4PLK1UniProtJ9P0Q41EQUAL603EQUALReactome DB_ID: 99428781Ghost homologue of PPP1CC [cytosol]Ghost homologue of PPP1CCReactome DB_ID: 99428721UniProt:E2R9K4XPO1UniProtE2R9K41EQUAL1071EQUALReactome DB_ID: 99428241UniProt:E2QWR3RCC2UniProtE2QWR31EQUAL522EQUALReactome DB_ID: 99430861Dynein complex [cytosol]Dynein complexConverted from EntitySet in ReactomeReactome DB_ID: 99430682DICs [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityDYNC1I1 [cytosol]DYNC1I2 [cytosol]UniProtF1PSE8UniProtE2RM92Reactome DB_ID: 99430581DHC dimer [cytosol]DHC dimerReactome DB_ID: 99430562UniProt:F1PGY9DYNC1H1UniProtF1PGY91EQUAL4646EQUALReactome Database ID Release 759943058Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943058ReactomeR-CFA-20291441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-2029144.1Converted from EntitySet in ReactomeReactome DB_ID: 99430842DLIs [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityDYNC1LI2 [cytosol]DYNC1LI1 [cytosol]UniProtF1P6V8UniProtE2RH71Converted from EntitySet in ReactomeReactome DB_ID: 99430742DLCs [cytosol]Converted from EntitySet in Reactome. Each synonym is a name of a PhysicalEntity, and each XREF points to one PhysicalEntityDYNLL1 [cytosol]DYNLL2 [cytosol]UniProtE2RK00UniProtE2RFR5Reactome Database ID Release 759943086Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943086ReactomeR-CFA-20291451Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-2029145.1Reactome DB_ID: 99430261Mitotic checkpoint complex [cytosol]Mitotic checkpoint complexReactome DB_ID: 99430201UniProt:F1PNG1BUB3UniProtF1PNG11EQUAL328EQUALReactome DB_ID: 994302411EQUAL499EQUALReactome DB_ID: 99430121UniProt:E2R3U8MAD2L1UniProtE2R3U82EQUAL205EQUALReactome DB_ID: 99430161UniProt:F1PLV9BUB1BUniProtF1PLV91EQUAL1050EQUALReactome Database ID Release 759943026Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943026ReactomeR-CFA-3778821Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377882.1Reactome DB_ID: 99430081Chromosome passenger complex [cytosol]Chromosome passenger complexReactome DB_ID: 994275011EQUAL918EQUALReactome DB_ID: 99430021Ghost homologue of BIRC5 [cytosol]Ghost homologue of BIRC5Reactome DB_ID: 99430001UniProt:E2QZL4AURKBUniProtE2QZL41EQUAL344EQUALReactome DB_ID: 99430061UniProt:E2R7G5CDCA8UniProtE2R7G51EQUAL280EQUALReactome Database ID Release 759943008Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943008ReactomeR-CFA-3778791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377879.1Reactome DB_ID: 99427601Ghost homologue of CENPF [cytosol]Ghost homologue of CENPFReactome DB_ID: 99427541UniProt:F1PPB3CENPAUniProtF1PPB31EQUAL140EQUALReactome DB_ID: 99428281UniProt:F1PRB2ZWINTUniProtF1PRB21EQUAL277EQUALReactome DB_ID: 99430401RZZ complex [cytosol]RZZ complexReactome DB_ID: 99430381UniProt:F6UZG3ZW10UniProtF6UZG32EQUAL779EQUALReactome DB_ID: 99430341UniProt:E2RC17ZWILCHUniProtE2RC171EQUAL591EQUALReactome DB_ID: 99430301UniProt:E2R234KNTC1UniProtE2R2341EQUAL2209EQUALReactome Database ID Release 759943040Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943040ReactomeR-CFA-3778851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377885.1Reactome DB_ID: 99428821UniProt:F1PVW6KIF2BUniProtF1PVW61EQUAL673EQUALReactome DB_ID: 99391781Nup107-160 complex [cytosol]Nup107-160 complexReactome DB_ID: 99391661UniProt:E2R488NUP37UniProtE2R4881EQUAL326EQUALReactome DB_ID: 99391481UniProt:F6V153NUP107UniProtF6V1531EQUAL925EQUALReactome DB_ID: 99391621UniProt:E2R4V6NUP98UniProtE2R4V61EQUAL880EQUALReactome DB_ID: 99391701UniProt:F1P643NUP43UniProtF1P6431EQUAL380EQUALReactome DB_ID: 99391741UniProt:F1PDM3SEC13UniProtF1PDM32EQUAL322EQUALReactome DB_ID: 99391561UniProt:F1PAZ3NUP160UniProtF1PAZ31EQUAL1436EQUALReactome DB_ID: 99391601UniProt:F1PFE9NUP85UniProtF1PFE91EQUAL656EQUALReactome DB_ID: 99391521UniProt:E2RB34NUP133UniProtE2RB341EQUAL1156EQUALReactome DB_ID: 99391761Ghost homologue of SEH1L-1 [cytosol]Ghost homologue of SEH1L-1Reactome Database ID Release 759939178Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9939178ReactomeR-CFA-3778831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-377883.1Reactome DB_ID: 99429001UniProt:F6V5M4NUDCUniProtF6V5M41EQUAL331EQUALReactome DB_ID: 99427881UniProt:E2QY31PAFAH1B1UniProtE2QY311EQUAL410EQUALReactome DB_ID: 99427681UniProt:J9P826CLASP2UniProtJ9P8261EQUAL1294EQUALReactome DB_ID: 99427721UniProt:F6Y5Z5EFCAB8UniProtF6Y5Z52EQUAL268EQUALReactome DB_ID: 99427761UniProt:J9JHE2AHCTF1UniProtJ9JHE21EQUAL2266EQUALReactome DB_ID: 99428041UniProt:J9NZ28RANGAP1UniProtJ9NZ282EQUAL587EQUALReactome DB_ID: 99428001UniProt:J9P9W5NDEL1UniProtJ9P9W51EQUAL345EQUALReactome DB_ID: 99391141UniProt:F1PA81RANBP2UniProtF1PA811EQUAL3224EQUALReactome Database ID Release 759943088Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943088ReactomeR-CFA-3753051Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-375305.1Reactome DB_ID: 994274611EQUAL718EQUALReactome DB_ID: 99430901Mad1:kinetochore complex [cytosol]Mad1:kinetochore complexReactome DB_ID: 99430881Reactome DB_ID: 994274611EQUAL718EQUALReactome Database ID Release 759943090Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943090ReactomeR-CFA-1414411Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-141441.1Reactome Database ID Release 759943092Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943092ReactomeR-CFA-1414091Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-141409.1The association of Mad1 with the kinetochore is the first step in the process of Mad2 mediated amplification of the signal from defective kinetochores.11181178Pubmed2001Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphaseCampbell, MSChan, GKYen, TimJ Cell Sci 114:953-63inferred by electronic annotationIEAGOIEA