BioPAX pathway converted from "Association of Securin with Cdc20:APC/C complex" in the Reactome database.Association of Securin with Cdc20:APC/C complexAssociation of Securin with Cdc20:APC/C complexThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 99464741cytosolGO0005829UniProt:E2RRF2PTTG1Reactomehttp://www.reactome.orgCanis familiarisNCBI Taxonomy9615UniProtE2RRF2Chain Coordinates1EQUAL202EQUALReactome DB_ID: 99465191CDC20:p-APC/C [cytosol]CDC20:p-APC/CReactome DB_ID: 99430241UniProt:E2RGS2CDC20UniProtE2RGS21EQUAL499EQUALReactome DB_ID: 99342691phosphorylated anaphase promoting complex (APC/C) [cytosol]phosphorylated anaphase promoting complex (APC/C)Reactome DB_ID: 99342391UniProt:J9P4C8CDC26UniProtJ9P4C81EQUAL85EQUALReactome DB_ID: 99342551UniProt:E2R4W0ANAPC11UniProtE2R4W01EQUAL84EQUALReactome DB_ID: 99342431UniProt:E2QXE6UBE2E1UniProtE2QXE62EQUAL193EQUALReactome DB_ID: 99342271UniProt:E2R5H6CDC16UniProtE2R5H61EQUAL620EQUALReactome DB_ID: 99342351UniProt:E2RHG6CDC23UniProtE2RHG61EQUAL597EQUALReactome DB_ID: 99342631UniProt:E2RKJ5ANAPC16UniProtE2RKJ52EQUAL110EQUALReactome DB_ID: 99342671UniProt:J9PAH6UBE2SUniProtJ9PAH61EQUAL222EQUALReactome DB_ID: 99342511UniProt:J9NTA2UBE2D1UniProtJ9NTA21EQUAL147EQUALReactome DB_ID: 99342591UniProt:E2QWL6ANAPC15UniProtE2QWL61EQUAL121EQUALReactome DB_ID: 99342191UniProt:E2R8L6ANAPC4UniProtE2R8L61EQUAL808EQUALReactome DB_ID: 99342031UniProt:E2RLM2ANAPC1UniProtE2RLM21EQUAL1944EQUALReactome DB_ID: 99342111UniProt:F1PYP1ANAPC2UniProtF1PYP11EQUAL822EQUALReactome DB_ID: 99342471UniProt:E2RN95UBE2CUniProtE2RN952EQUAL179EQUALReactome DB_ID: 99342151UniProt:F1Q3E7CDC27UniProtF1Q3E71EQUAL824EQUALReactome DB_ID: 99342231UniProt:E2R4S0ANAPC5UniProtE2R4S01EQUAL755EQUALReactome DB_ID: 99342071UniProt:E2R745ANAPC10UniProtE2R7451EQUAL185EQUALReactome DB_ID: 99342311UniProt:E2R9A5ANAPC7UniProtE2R9A51EQUAL599EQUALReactome Database ID Release 759934269Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934269ReactomeR-CFA-1741911Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174191.1Reactome Database ID Release 759946519Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946519ReactomeR-CFA-1740811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174081.1Reactome DB_ID: 99465251CDC20:p-APC/C:PTTG1 [cytosol]CDC20:p-APC/C:PTTG1Reactome DB_ID: 994647411EQUAL202EQUALReactome DB_ID: 99465191Reactome Database ID Release 759946525Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946525ReactomeR-CFA-1742121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174212.1Reactome Database ID Release 759946527Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946527ReactomeR-CFA-1741211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174121.1Securin is thought to be recognized by the APC/C:Cdc20 complex through its conserved D-box sequence.12070128Pubmed2002Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1Hagting, ADen Elzen, NVodermaier, HCWaizenegger, ICPeters, JMPines, JJ Cell Biol 157:1125-37inferred by electronic annotationIEAGOIEA