BioPAX pathway converted from "WWTR1 (TAZ) binds ZO-2 (TJP2)" in the Reactome database. WWTR1 (TAZ) binds ZO-2 (TJP2) WWTR1 (TAZ) binds ZO-2 (TJP2) This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> Reactome DB_ID: 9984744 1 cytosol GO 0005829 UniProt:Q3ZB99 Tjp2 Reactome http://www.reactome.org Rattus norvegicus NCBI Taxonomy 10116 UniProt Q3ZB99 Chain Coordinates 1 EQUAL 1190 EQUAL Reactome DB_ID: 9984123 1 UniProt:Q4V7E6 Wwtr1 UniProt Q4V7E6 1 EQUAL 400 EQUAL Reactome DB_ID: 9984760 1 WWTR1:TJP2 [cytosol] WWTR1:TJP2 Reactome DB_ID: 9984744 1 1 EQUAL 1190 EQUAL Reactome DB_ID: 9984123 1 1 EQUAL 400 EQUAL Reactome Database ID Release 82 9984760 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9984760 Reactome R-RNO-2064405 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-2064405.1 Reactome Database ID Release 82 9984762 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9984762 Reactome R-RNO-2064418 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-2064418.1 Cytosolic ZO-2 (TJP2) binds WWTR1 (TAZ) to form a complex. This event may play a role in sequestering WWTR1 in the cytosol (Remue et al. 2010). The phosphorylation state of the WWTR1 protein involved in this interaction has not been determined experimentally; it is inferred to be unphosphorylated. 20850437 Pubmed 2010 TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner Remue, E Meerschaert, K Oka, T Boucherie, C Vandekerckhove, J Sudol, M Gettemans, J FEBS Lett 584:4175-80 inferred by electronic annotation IEA GO IEA