BioPAX pathway converted from "WWTR1 (TAZ) binds ZO-2 (TJP2)" in the Reactome database. LEFT-TO-RIGHT WWTR1 (TAZ) binds ZO-2 (TJP2) This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> TJP2 TJP2 A0A3Q1MEH9 Reactome DB_ID: 10193780 cytosol GENE ONTOLOGY GO:0005829 UniProt:A0A3Q1MEH9 TJP2 Bos taurus NCBI Taxonomy 9913 UniProt A0A3Q1MEH9 1 EQUAL 1190 EQUAL Reactome Database ID Release 82 10193780 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10193780 Reactome R-BTA-2064412 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-2064412.1 Reactome http://www.reactome.org WWTR1 WWTR1 A0A3Q1NBB6 Reactome DB_ID: 10193176 UniProt:A0A3Q1NBB6 WWTR1 UniProt A0A3Q1NBB6 1 EQUAL 400 EQUAL Reactome Database ID Release 82 10193176 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10193176 Reactome R-BTA-1629773 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-1629773.1 WWTR1:TJP2 Reactome DB_ID: 10193790 1 1 Reactome Database ID Release 82 10193790 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10193790 Reactome R-BTA-2064405 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-2064405.1 Reactome Database ID Release 82 10193792 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10193792 Reactome R-BTA-2064418 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-2064418.1 Cytosolic ZO-2 (TJP2) binds WWTR1 (TAZ) to form a complex. This event may play a role in sequestering WWTR1 in the cytosol (Remue et al. 2010). The phosphorylation state of the WWTR1 protein involved in this interaction has not been determined experimentally; it is inferred to be unphosphorylated. 20850437 Pubmed 2010 TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner Remue, E Meerschaert, K Oka, T Boucherie, C Vandekerckhove, J Sudol, M Gettemans, J FEBS Lett 584:4175-80 inferred from electronic annotation EVIDENCE CODE ECO:0000203