BioPAX pathway converted from "EP1 receptor can bind PGE2" in the Reactome database.LEFT-TO-RIGHTEP1 receptor can bind PGE2This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>PGE2prostaglandin E2Reactome DB_ID: 391930extracellular regionGENE ONTOLOGYGO:0005576prostaglandin E2 [ChEBI:15551]prostaglandin E2ChEBICHEBI:15551Reactome Database ID Release 75391930Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=391930ReactomeR-ALL-3919303Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-391930.3Reactomehttp://www.reactome.orgPTGER1ptger1aF1QIS8Reactome DB_ID: 10215991plasma membraneGENE ONTOLOGYGO:0005886UniProt:F1QIS8ptger1aDanio rerioNCBI Taxonomy7955UniProtF1QIS81EQUAL402EQUALReactome Database ID Release 7510215991Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10215991ReactomeR-DRE-3918381Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-391838.1PTGER1:PGE2Reactome DB_ID: 1021599311Reactome Database ID Release 7510215993Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10215993ReactomeR-DRE-3919201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-391920.1Reactome Database ID Release 7510219298Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10219298ReactomeR-DRE-3919361Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-391936.1The EP1 protein (Funk CD et al, 1993) is one of four receptors identified for prostaglandin E2 (PGE2). The effects of PGE2 are mediated through the G protein g alpha q/11 subunits and the subsequent phosphatidylinositol-calcium second messenger system (Funk CD et al, 1993).8253813Pubmed1993Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtypeFunk, CDFurci, LFitzGerald, GAGrygorczyk, RRochette, CBayne, MAAbramovitz, MAdam, MMetters, KMJ Biol Chem 268:26767-72inferred from electronic annotationEVIDENCE CODEECO:0000203