BioPAX pathway converted from "POM121 and NDC1 bind the Nup93 complex" in the Reactome database. LEFT-TO-RIGHT POM121 and NDC1 bind the Nup93 complex This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> NDC1 NDC1 A0A3Q1M337 Reactome DB_ID: 10146031 nuclear envelope GENE ONTOLOGY GO:0005635 UniProt:A0A3Q1M337 NDC1 Bos taurus NCBI Taxonomy 9913 UniProt A0A3Q1M337 1 EQUAL 674 EQUAL Reactome Database ID Release 82 10146031 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146031 Reactome R-BTA-6805183 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-6805183.1 Reactome http://www.reactome.org 32 NUP188 NUP188 F1N6B6 Reactome DB_ID: 10241378 cytosol GENE ONTOLOGY GO:0005829 UniProt:F1N6B6 NUP188 UniProt F1N6B6 2 EQUAL 1749 EQUAL Reactome Database ID Release 82 10241378 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241378 Reactome R-BTA-9634172 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634172.1 16 POM121:Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10240998 POM121 LOC518768 E1BG57 Reactome DB_ID: 10146025 UniProt:E1BG57 LOC518768 UniProt E1BG57 1 EQUAL 1249 EQUAL Reactome Database ID Release 82 10146025 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146025 Reactome R-BTA-157747 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-157747.1 16 Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10240942 Nup107-160 complex Reactome DB_ID: 10146065 SEH1L SEH1L-1 A7YY75 Reactome DB_ID: 10146063 UniProt:A7YY75 SEH1L UniProt A7YY75 1 EQUAL 360 EQUAL Reactome Database ID Release 82 10146063 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146063 Reactome R-BTA-376246 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376246.1 1 NUP107 NUP107 E1BDU0 Reactome DB_ID: 10146035 UniProt:E1BDU0 NUP107 UniProt E1BDU0 1 EQUAL 925 EQUAL Reactome Database ID Release 82 10146035 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146035 Reactome R-BTA-376241 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376241.1 1 NUP85 NUP85 Q3ZC98 Reactome DB_ID: 10146047 UniProt:Q3ZC98 NUP85 UniProt Q3ZC98 1 EQUAL 656 EQUAL Reactome Database ID Release 82 10146047 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146047 Reactome R-BTA-376238 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376238.1 1 NUP98 NUP98-5 E1BCV4 Reactome DB_ID: 10146049 UniProt:E1BCV4 NUP98 UniProt E1BCV4 1 EQUAL 880 EQUAL Reactome Database ID Release 82 10146049 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146049 Reactome R-BTA-376247 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376247.1 1 NUP43 NUP43 A3KMW1 Reactome DB_ID: 10146057 UniProt:A3KMW1 NUP43 UniProt A3KMW1 1 EQUAL 380 EQUAL Reactome Database ID Release 82 10146057 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146057 Reactome R-BTA-376243 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376243.1 1 NUP133 NUP133 F1MM55 Reactome DB_ID: 10146039 UniProt:F1MM55 NUP133 UniProt F1MM55 1 EQUAL 1156 EQUAL Reactome Database ID Release 82 10146039 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146039 Reactome R-BTA-376251 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376251.1 1 NUP37 NUP37 E1BD42 Reactome DB_ID: 10146053 UniProt:E1BD42 NUP37 UniProt E1BD42 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10146053 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146053 Reactome R-BTA-376237 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376237.1 1 SEC13 SEC13 Q3ZCC9 Reactome DB_ID: 10146061 UniProt:Q3ZCC9 SEC13 UniProt Q3ZCC9 2 EQUAL 322 EQUAL Reactome Database ID Release 82 10146061 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146061 Reactome R-BTA-203981 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-203981.1 1 NUP160 NUP160 F1MZR0 Reactome DB_ID: 10146043 UniProt:F1MZR0 NUP160 UniProt F1MZR0 1 EQUAL 1436 EQUAL Reactome Database ID Release 82 10146043 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146043 Reactome R-BTA-376253 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376253.1 1 Reactome Database ID Release 82 10146065 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10146065 Reactome R-BTA-377883 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-377883.1 32 Converted from EntitySet in Reactome Chromatin Reactome DB_ID: 2537690 Sister Centromere Reactome DB_ID: 1638792 chromosome GENE ONTOLOGY GO:0005694 Reactome Database ID Release 82 1638792 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638792 Reactome R-ALL-1638792 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638792.3 ChEBI 23367 additional information MI MI:0361 Sister Chromatid Sister Chromosomal Arm Reactome DB_ID: 1638790 Reactome Database ID Release 82 1638790 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638790 Reactome R-ALL-1638790 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638790.3 ChEBI 23367 Reactome Database ID Release 82 2537690 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2537690 Reactome R-ALL-2537690 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-2537690.1 1 AHCTF1 AHCTF1 A0A3Q1MMV9 Reactome DB_ID: 10150036 UniProt:A0A3Q1MMV9 AHCTF1 UniProt A0A3Q1MMV9 1 EQUAL 2266 EQUAL Reactome Database ID Release 82 10150036 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10150036 Reactome R-BTA-376244 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-376244.1 16 Reactome Database ID Release 82 10240942 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10240942 Reactome R-BTA-9615902 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9615902.1 1 Reactome Database ID Release 82 10240998 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10240998 Reactome R-BTA-9618374 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9618374.1 Nup93 complex Reactome DB_ID: 10241376 NUP93 NUP93 A5PJZ5 Reactome DB_ID: 10241374 UniProt:A5PJZ5 NUP93 UniProt A5PJZ5 1 EQUAL 819 EQUAL Reactome Database ID Release 82 10241374 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241374 Reactome R-BTA-9634167 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634167.1 1 NUP205 NUP205 A0A3Q1N4S4 Reactome DB_ID: 10241370 UniProt:A0A3Q1N4S4 NUP205 UniProt A0A3Q1N4S4 2 EQUAL 2012 EQUAL Reactome Database ID Release 82 10241370 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241370 Reactome R-BTA-9634168 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634168.1 1 NUP35 NUP35 F6QU27 Reactome DB_ID: 10241372 UniProt:F6QU27 NUP35 UniProt F6QU27 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10241372 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241372 Reactome R-BTA-9634171 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634171.1 1 NUP155 NUP155 A0A3Q1M9F3 Reactome DB_ID: 10241368 UniProt:A0A3Q1M9F3 NUP155 UniProt A0A3Q1M9F3 1 EQUAL 1391 EQUAL Reactome Database ID Release 82 10241368 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241368 Reactome R-BTA-9634170 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634170.1 1 Reactome Database ID Release 82 10241376 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241376 Reactome R-BTA-9634166 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634166.1 32 Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin Reactome DB_ID: 10241380 32 16 1 32 Reactome Database ID Release 82 10241380 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241380 Reactome R-BTA-9634164 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634164.1 Reactome Database ID Release 82 10241382 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10241382 Reactome R-BTA-9634169 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-BTA-9634169.1 From studies with Xenopus and human model systems, the transmembrane nucleoporins POM121 and NDC1 recruit the NUP93 complex to nascent nuclear pore complexes (NPCs) due to interaction with the NUP93 complex components NUP155 (Mitchell et al. 2010) and, potentially, NUP35 (Mansfield et al. 2006). This is consistent with order-of-assembly seen in live cell imaging (Dultz et al. 2008). 18316408 Pubmed 2008 Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells Dultz, Elisa Zanin, Esther Wurzenberger, Claudia Braun, Marion Rabut, Gwénaël Sironi, Lucia Ellenberg, Jan J. Cell Biol. 180:857-65 20974814 Pubmed 2010 Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane Mitchell, Jana M Mansfeld, Jörg Capitanio, Juliana Kutay, Ulrike Wozniak, Richard W J. Cell Biol. 191:505-21 16600873 Pubmed 2006 The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells Mansfeld, Jörg Güttinger, Stephan Hawryluk-Gara, Lisa A Panté, Nelly Mall, Moritz Galy, Vincent Haselmann, Uta Mühlhäusser, Petra Wozniak, Richard W Mattaj, Iain W Kutay, Ulrike Antonin, Wolfram Mol. Cell 22:93-103 inferred from electronic annotation EVIDENCE CODE ECO:0000203