BioPAX pathway converted from "PTK6 phosphorylates STAP2" in the Reactome database.
LEFT-TO-RIGHT
2.7.10.2
BRK phosphorylates STAP2
PTK6 phosphorylates STAP2
This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>
p-Y342-PTK6:STAP2
Reactome DB_ID: 10404998
cytosol
GENE ONTOLOGY
GO:0005829
Converted from EntitySet in Reactome
Homologues of p-Y342-PTK6
Reactome DB_ID: 10404989
F1Q7D7
phospho-ptk6a
p-Y342-PTK6
Reactome DB_ID: 10404984
UniProt:F1Q7D7
ptk6a
Danio rerio
NCBI Taxonomy
7955
UniProt
F1Q7D7
342
EQUAL
O4'-phospho-L-tyrosine
MOD
MOD:00048
1
EQUAL
451
EQUAL
Reactome Database ID Release 81
10404984
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10404984
Reactome
R-DRE-8848007
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848007.1
Reactome
http://www.reactome.org
Q08BY6
phospho-ptk6b
p-Y342-PTK6
Reactome DB_ID: 10404987
UniProt:Q08BY6
ptk6b
UniProt
Q08BY6
342
EQUAL
1
EQUAL
451
EQUAL
Reactome Database ID Release 81
10404987
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10404987
Reactome
R-DRE-8848007-2
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848007-2.1
Reactome Database ID Release 81
10404989
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10404989
Reactome
R-DRE-8848007-3
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848007-3.1
1
STAP2
stap2a
Q7T2F4
Reactome DB_ID: 10404996
UniProt:Q7T2F4
stap2a
UniProt
Q7T2F4
1
EQUAL
403
EQUAL
Reactome Database ID Release 81
10404996
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10404996
Reactome
R-DRE-8848028
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848028.1
1
Reactome Database ID Release 81
10404998
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10404998
Reactome
R-DRE-8848029
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848029.1
ATP
Adenosine 5'-triphosphate
ATP(4-)
Reactome DB_ID: 113592
ATP(4-) [ChEBI:30616]
ATP(4-)
ATP
atp
Adenosine 5'-triphosphate
ChEBI
CHEBI:30616
Reactome Database ID Release 81
113592
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113592
Reactome
R-ALL-113592
5
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-113592.5
COMPOUND
C00002
additional information
MI
MI:0361
p-Y342-PTK6:p-Y250-STAP2
Reactome DB_ID: 10405010
Q7T2F4
phospho-stap2a
p-Y250-STAP2
Reactome DB_ID: 10405008
plasma membrane
GENE ONTOLOGY
GO:0005886
250
EQUAL
1
EQUAL
403
EQUAL
Reactome Database ID Release 81
10405008
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10405008
Reactome
R-DRE-8848079
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848079.1
1
1
Reactome Database ID Release 81
10405010
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10405010
Reactome
R-DRE-8848073
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848073.1
ADP
Adenosine 5'-diphosphate
ADP(3-)
Reactome DB_ID: 29370
ADP(3-) [ChEBI:456216]
ADP(3-)
ADP
5'-O-[(phosphonatooxy)phosphinato]adenosine
ADP trianion
ChEBI
CHEBI:456216
Reactome Database ID Release 81
29370
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29370
Reactome
R-ALL-29370
5
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-29370.5
COMPOUND
C00008
ACTIVATION
activeUnit: #Protein1
GENE ONTOLOGY
GO:0004713
gene ontology term for cellular function
MI
MI:0355
Same Catalyst Activity
Reactome Database ID Release 81
10405011
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10405011
Reactome Database ID Release 81
10405013
Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10405013
Reactome
R-DRE-8848077
1
Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-8848077.1
Activated PTK6 (BRK) phosphorylates STAP2 at tyrosine residue Y250 (Ikeda et al. 2009).
19393627
Pubmed
2009
STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation
Ikeda, Osamu
Miyasaka, Yuto
Sekine, Yuichi
Mizushima, Akihiro
Muromoto, Ryuta
Nanbo, Asuka
Yoshimura, A
Matsuda, Tadashi
Biochem. Biophys. Res. Commun. 384:71-5
inferred from electronic annotation
EVIDENCE CODE
ECO:0000203