BioPAX pathway converted from "Translocation of YAP1:ZO-2 (TJP2) to the nucleus" in the Reactome database. LEFT-TO-RIGHT Translocation of YAP1:ZO-2 (TJP2) to the nucleus This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> YAP1:TJP2 Reactome DB_ID: 10410541 cytosol GENE ONTOLOGY GO:0005829 TJP2 A0A2R8QB05 Reactome DB_ID: 10410539 UniProt:A0A2R8QB05 Danio rerio NCBI Taxonomy 7955 UniProt A0A2R8QB05 1 EQUAL 1190 EQUAL Reactome Database ID Release 82 10410539 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410539 Reactome R-DRE-2064412 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064412.1 Reactome http://www.reactome.org 1 yap1 YAP1 Q1L8J7 Reactome DB_ID: 10399972 UniProt:Q1L8J7 yap1 UniProt Q1L8J7 1 EQUAL 504 EQUAL Reactome Database ID Release 82 10399972 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10399972 Reactome R-DRE-1253345 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-1253345.1 1 Reactome Database ID Release 82 10410541 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410541 Reactome R-DRE-2064400 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064400.1 YAP1:TJP2 Reactome DB_ID: 10410545 nucleoplasm GENE ONTOLOGY GO:0005654 yap1 YAP1 Q1L8J7 Reactome DB_ID: 10399976 1 EQUAL 504 EQUAL Reactome Database ID Release 82 10399976 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10399976 Reactome R-DRE-1253322 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-1253322.1 1 TJP2 A0A2R8QB05 Reactome DB_ID: 10410543 1 EQUAL 1190 EQUAL Reactome Database ID Release 82 10410543 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410543 Reactome R-DRE-2064410 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064410.1 1 Reactome Database ID Release 82 10410545 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410545 Reactome R-DRE-2064401 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064401.1 Reactome Database ID Release 82 10410547 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10410547 Reactome R-DRE-2064406 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-2064406.1 The YAP1:ZO-2 (TJP2) complex can translocate to the nucleus (Oka et al. 2010). 20868367 Pubmed 2010 Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling Oka, T Remue, E Meerschaert, K Vanloo, B Boucherie, C Gfeller, D Bader, GD Sidhu, SS Vandekerckhove, J Gettemans, J Sudol, M Biochem J 432:461-72 inferred from electronic annotation EVIDENCE CODE ECO:0000203