BioPAX pathway converted from "POM121 and NDC1 bind the Nup93 complex" in the Reactome database. LEFT-TO-RIGHT POM121 and NDC1 bind the Nup93 complex This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> ndc1 NDC1 Q7SZC5 Reactome DB_ID: 10359280 nuclear envelope GENE ONTOLOGY GO:0005635 UniProt:Q7SZC5 ndc1 Danio rerio NCBI Taxonomy 7955 UniProt Q7SZC5 1 EQUAL 674 EQUAL Reactome Database ID Release 82 10359280 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359280 Reactome R-DRE-6805183 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-6805183.1 Reactome http://www.reactome.org 32 Nup93 complex Reactome DB_ID: 10463388 cytosol GENE ONTOLOGY GO:0005829 nup35 NUP35 Q6P6X9 Reactome DB_ID: 10463384 UniProt:Q6P6X9 nup35 UniProt Q6P6X9 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10463384 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463384 Reactome R-DRE-9634171 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634171.1 1 NUP155 F1Q953 Reactome DB_ID: 10463380 UniProt:F1Q953 UniProt F1Q953 1 EQUAL 1391 EQUAL Reactome Database ID Release 82 10463380 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463380 Reactome R-DRE-9634170 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634170.1 1 dye NUP93 Q7ZU29 Reactome DB_ID: 10463386 UniProt:Q7ZU29 dye UniProt Q7ZU29 1 EQUAL 819 EQUAL Reactome Database ID Release 82 10463386 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463386 Reactome R-DRE-9634167 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634167.1 1 NUP205 A0A2R8QTU4 Reactome DB_ID: 10463382 UniProt:A0A2R8QTU4 UniProt A0A2R8QTU4 2 EQUAL 2012 EQUAL Reactome Database ID Release 82 10463382 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463382 Reactome R-DRE-9634168 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634168.1 1 Reactome Database ID Release 82 10463388 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463388 Reactome R-DRE-9634166 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634166.1 32 POM121:Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10463023 Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10462971 AHCTF1 X1WE68 Reactome DB_ID: 10363413 UniProt:X1WE68 UniProt X1WE68 1 EQUAL 2266 EQUAL Reactome Database ID Release 82 10363413 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10363413 Reactome R-DRE-376244 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376244.1 16 Nup107-160 complex Reactome DB_ID: 10359314 nup133 NUP133 F1QNV4 Reactome DB_ID: 10359288 UniProt:F1QNV4 nup133 UniProt F1QNV4 1 EQUAL 1156 EQUAL Reactome Database ID Release 82 10359288 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359288 Reactome R-DRE-376251 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376251.1 1 seh1l SEH1L-1 Q6TGU2 Reactome DB_ID: 10359312 UniProt:Q6TGU2 seh1l UniProt Q6TGU2 1 EQUAL 360 EQUAL Reactome Database ID Release 82 10359312 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359312 Reactome R-DRE-376246 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376246.1 1 NUP43 Q5RFW3 Reactome DB_ID: 10359306 UniProt:Q5RFW3 UniProt Q5RFW3 1 EQUAL 380 EQUAL Reactome Database ID Release 82 10359306 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359306 Reactome R-DRE-376243 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376243.1 1 SEC13 A0A2R8RKG2 Reactome DB_ID: 10359310 UniProt:A0A2R8RKG2 UniProt A0A2R8RKG2 2 EQUAL 322 EQUAL Reactome Database ID Release 82 10359310 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359310 Reactome R-DRE-203981 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-203981.1 1 NUP160 A0A2R8Q4U1 Reactome DB_ID: 10359292 UniProt:A0A2R8Q4U1 UniProt A0A2R8Q4U1 1 EQUAL 1436 EQUAL Reactome Database ID Release 82 10359292 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359292 Reactome R-DRE-376253 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376253.1 1 nup85 NUP85 Q6DBY0 Reactome DB_ID: 10359296 UniProt:Q6DBY0 nup85 UniProt Q6DBY0 1 EQUAL 656 EQUAL Reactome Database ID Release 82 10359296 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359296 Reactome R-DRE-376238 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376238.1 1 E7F981 NUP98-5 Reactome DB_ID: 10359298 UniProt:E7F981 UniProt E7F981 1 EQUAL 880 EQUAL Reactome Database ID Release 82 10359298 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359298 Reactome R-DRE-376247 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376247.1 1 NUP107 Q5RGI2 Reactome DB_ID: 10359284 UniProt:Q5RGI2 UniProt Q5RGI2 1 EQUAL 925 EQUAL Reactome Database ID Release 82 10359284 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359284 Reactome R-DRE-376241 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376241.1 1 NUP37 J3JS14 Reactome DB_ID: 10359302 UniProt:J3JS14 UniProt J3JS14 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10359302 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359302 Reactome R-DRE-376237 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-376237.1 1 Reactome Database ID Release 82 10359314 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359314 Reactome R-DRE-377883 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-377883.1 32 Converted from EntitySet in Reactome Chromatin Reactome DB_ID: 2537690 Sister Centromere Reactome DB_ID: 1638792 chromosome GENE ONTOLOGY GO:0005694 Reactome Database ID Release 82 1638792 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638792 Reactome R-ALL-1638792 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638792.3 ChEBI 23367 additional information MI MI:0361 Sister Chromatid Sister Chromosomal Arm Reactome DB_ID: 1638790 Reactome Database ID Release 82 1638790 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638790 Reactome R-ALL-1638790 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638790.3 ChEBI 23367 Reactome Database ID Release 82 2537690 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2537690 Reactome R-ALL-2537690 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-2537690.1 1 Reactome Database ID Release 82 10462971 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10462971 Reactome R-DRE-9615902 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9615902.1 1 POM121 F1R543 Reactome DB_ID: 10359272 UniProt:F1R543 UniProt F1R543 1 EQUAL 1249 EQUAL Reactome Database ID Release 82 10359272 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10359272 Reactome R-DRE-157747 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-157747.1 16 Reactome Database ID Release 82 10463023 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463023 Reactome R-DRE-9618374 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9618374.1 NUP188 E7EXJ6 Reactome DB_ID: 10463390 UniProt:E7EXJ6 UniProt E7EXJ6 2 EQUAL 1749 EQUAL Reactome Database ID Release 82 10463390 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463390 Reactome R-DRE-9634172 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634172.1 16 Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin Reactome DB_ID: 10463392 32 32 1 16 Reactome Database ID Release 82 10463392 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463392 Reactome R-DRE-9634164 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634164.1 Reactome Database ID Release 82 10463394 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10463394 Reactome R-DRE-9634169 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DRE-9634169.1 From studies with Xenopus and human model systems, the transmembrane nucleoporins POM121 and NDC1 recruit the NUP93 complex to nascent nuclear pore complexes (NPCs) due to interaction with the NUP93 complex components NUP155 (Mitchell et al. 2010) and, potentially, NUP35 (Mansfield et al. 2006). This is consistent with order-of-assembly seen in live cell imaging (Dultz et al. 2008). 18316408 Pubmed 2008 Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells Dultz, Elisa Zanin, Esther Wurzenberger, Claudia Braun, Marion Rabut, Gwénaël Sironi, Lucia Ellenberg, Jan J. Cell Biol. 180:857-65 20974814 Pubmed 2010 Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane Mitchell, Jana M Mansfeld, Jörg Capitanio, Juliana Kutay, Ulrike Wozniak, Richard W J. Cell Biol. 191:505-21 16600873 Pubmed 2006 The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells Mansfeld, Jörg Güttinger, Stephan Hawryluk-Gara, Lisa A Panté, Nelly Mall, Moritz Galy, Vincent Haselmann, Uta Mühlhäusser, Petra Wozniak, Richard W Mattaj, Iain W Kutay, Ulrike Antonin, Wolfram Mol. Cell 22:93-103 inferred from electronic annotation EVIDENCE CODE ECO:0000203