BioPAX pathway converted from "SLAMF6 binds SLAMF6" in the Reactome database.LEFT-TO-RIGHTSLAMF6 binds SLAMF6This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Converted from EntitySet in ReactomeHomologues of SLAMF6Reactome DB_ID: 10467031SLAMF6A0A1D5P6E0Reactome DB_ID: 10467027plasma membraneGENE ONTOLOGYGO:0005886UniProt:A0A1D5P6E0Gallus gallusNCBI Taxonomy9031UniProtA0A1D5P6E022EQUAL332EQUALReactome Database ID Release 7510467027Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10467027ReactomeR-GGA-1978481Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-197848.1Reactomehttp://www.reactome.orgSLAMF6K4L906Reactome DB_ID: 10467029UniProt:K4L906UniProtK4L90622EQUAL332EQUALReactome Database ID Release 7510467029Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10467029ReactomeR-GGA-197848-21Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-197848-2.1Reactome Database ID Release 7510467031Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10467031ReactomeR-GGA-197848-31Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-197848-3.12SLAMF6 dimerReactome DB_ID: 104670332Reactome Database ID Release 7510467033Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10467033ReactomeR-GGA-56852291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-5685229.1Reactome Database ID Release 7510467039Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10467039ReactomeR-GGA-56856041Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-5685604.1Members of the signaling lymphocytic-activation molecule (SLAM) family, are all encoded in the SLAM locus, and are mostly homotypic self-associating receptors expressed by cells of hemopoietic origin (Veillette et al. 2006). SLAMF6 (also called as NTB-A) is a homophilic receptor that stimulates cytotoxicity in natural killer (NK) cells, regulates bactericidal activities in neutrophils, and potentiates T helper 2 (Th2) responses (Cao et al. 2006).17045824Pubmed2006NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor familyCao, ErhuRamagopal, Udupi AFedorov, AlexanderFedorov, ElenaYan, QingrongLary, Jeffrey WCole, James LNathenson, Stanley GAlmo, Steven CImmunity 25:559-7018031695Pubmed2007Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentGriewank, KlausBorowski, ChristineRietdijk, SvendWang, NinghaiJulien, AimeeWei, Datsen GMamchak, Alusha ATerhorst, CoxBendelac, AlbertImmunity 27:751-6216493427Pubmed2006Immune regulation by SLAM family receptors and SAP-related adaptorsVeillette, AndréNat. Rev. Immunol. 6:56-66inferred from electronic annotationEVIDENCE CODEECO:0000203