BioPAX pathway converted from "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)" in the Reactome database.LEFT-TO-RIGHT1.3.3(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>O2OxygendioxygenReactome DB_ID: 113535peroxisomal matrixGENE ONTOLOGYGO:0005782dioxygen [ChEBI:15379]dioxygenChEBICHEBI:15379Reactome Database ID Release 75113535Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113535ReactomeR-ALL-1135353Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-113535.3Reactomehttp://www.reactome.orgCOMPOUNDC00007additional informationMIMI:0361(2S) Pristanoyl-CoA(2S)-pristanoyl-CoAReactome DB_ID: 389893(2S)-pristanoyl-CoA [ChEBI:64039](2S)-pristanoyl-CoA(2S)-pristanoyl-coenzyme A(2S)-2,6,10,14-tetramethylpentadecanoyl-coenzyme A(2S)-2,6,10,14-tetramethylpentadecanoyl-CoAChEBICHEBI:64039Reactome Database ID Release 75389893Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389893ReactomeR-ALL-3898933Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-389893.3H2O2hydrogen peroxideReactome DB_ID: 113575hydrogen peroxide [ChEBI:16240]hydrogen peroxideChEBICHEBI:16240Reactome Database ID Release 75113575Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113575ReactomeR-ALL-1135753Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-113575.3COMPOUNDC00027trans-2,3-dehydropristanoyl-CoA(E)-2,3-didehydropristanoyl-CoAReactome DB_ID: 389894(E)-2,3-didehydropristanoyl-CoA [ChEBI:63803](E)-2,3-didehydropristanoyl-CoAtrans-2,3-didehydropristanoyl-CoAtrans-2,3-dehydropristanoyl-CoAChEBICHEBI:63803Reactome Database ID Release 75389894Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389894ReactomeR-ALL-3898943Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-389894.3ACTIVATIONACOX3:FADReactome DB_ID: 10658135Converted from EntitySet in ReactomeHomologues of ACOX3Reactome DB_ID: 10658133ACOX3B0G110Reactome DB_ID: 10658114UniProt:B0G110Dictyostelium discoideumNCBI Taxonomy44689UniProtB0G1101EQUAL700EQUALReactome Database ID Release 7510658114Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658114ReactomeR-DDI-3898841Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884.1ACOX3Q54II1Reactome DB_ID: 10658116UniProt:Q54II1UniProtQ54II11EQUAL700EQUALReactome Database ID Release 7510658116Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658116ReactomeR-DDI-389884-21Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884-2.1acoAACOX3Q54RB0Reactome DB_ID: 10658121UniProt:Q54RB0acoAUniProtQ54RB01EQUAL700EQUALReactome Database ID Release 7510658121Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658121ReactomeR-DDI-389884-31Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884-3.1ACOX3Q75JL8Reactome DB_ID: 10658126UniProt:Q75JL8UniProtQ75JL81EQUAL700EQUALReactome Database ID Release 7510658126Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658126ReactomeR-DDI-389884-41Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884-4.1ACOX3Q8MMS1Reactome DB_ID: 10658131UniProt:Q8MMS1UniProtQ8MMS11EQUAL700EQUALReactome Database ID Release 7510658131Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658131ReactomeR-DDI-389884-51Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884-5.1Reactome Database ID Release 7510658133Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658133ReactomeR-DDI-389884-61Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389884-6.11FADReactome DB_ID: 141335FAD [ChEBI:16238]FADFlavin adenine dinucleotideChEBICHEBI:16238Reactome Database ID Release 75141335Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=141335ReactomeR-ALL-1413352Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-141335.21Reactome Database ID Release 7510658135Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658135ReactomeR-DDI-3899051Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389905.1GENE ONTOLOGYGO:0016402gene ontology term for cellular functionMIMI:0355Same Catalyst ActivityReactome Database ID Release 7510658136Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658136Reactome Database ID Release 7510658138Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10658138ReactomeR-DDI-3898911Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DDI-389891.1Peroxisomal ACOX3 catalyzes the reaction of (2S)-pristanoyl-CoA and O2 to form trans-2,3-dehydropristanoyl-CoA and H2O2. ACOX3 protein and enzyme activity have been observed in prostate tumors, but are undetectable in normal prostate tissue as well as in liver and kidney (where ACOX2 catalyzes the oxidation of pristanoyl-CoA) (Zha et al. 2005; Vanhooren et al. 1997). The physiological consequences of this differential gene expression are unknown.9271077Pubmed1997Evidence for the existence of a pristanoyl-CoA oxidase gene in manVanhooren, JCMarynen, PMannaerts, Guy PVan Veldhoven, Paul PBiochem J 325:593-915599942Pubmed2005Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancerZha, SFerdinandusse, SachaHicks, JLDenis, SimoneDunn, TAWanders, Ronald J ALuo, JDe Marzo, AMIsaacs, WBProstate 63:316-23inferred from electronic annotationEVIDENCE CODEECO:0000203