BioPAX pathway converted from "POM121 and NDC1 bind the Nup93 complex" in the Reactome database. LEFT-TO-RIGHT POM121 and NDC1 bind the Nup93 complex This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> NDC1 cut11 O13961 Reactome DB_ID: 10870508 nuclear envelope GENE ONTOLOGY GO:0005635 UniProt:O13961 cut11 Schizosaccharomyces pombe NCBI Taxonomy 4896 UniProt O13961 1 EQUAL 674 EQUAL Reactome Database ID Release 82 10870508 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870508 Reactome R-SPO-6805183 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-6805183.1 Reactome http://www.reactome.org 32 POM121:Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10890864 Ghost homologue of POM121 Reactome DB_ID: 10870503 Reactome Database ID Release 82 10870503 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870503 Reactome R-SPO-6805169 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-6805169.1 16 Nup107-160 complex:AHCTF1:Chromatin Reactome DB_ID: 10890766 cytosol GENE ONTOLOGY GO:0005829 Nup107-160 complex Reactome DB_ID: 10870549 nup85 NUP85 Q9UUE5 Reactome DB_ID: 10870528 UniProt:Q9UUE5 nup85 UniProt Q9UUE5 1 EQUAL 656 EQUAL Reactome Database ID Release 82 10870528 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870528 Reactome R-SPO-376238 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376238.1 1 seh1 SEH1L-1 Q10099 Reactome DB_ID: 10870547 UniProt:Q10099 seh1 UniProt Q10099 1 EQUAL 360 EQUAL Reactome Database ID Release 82 10870547 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870547 Reactome R-SPO-376246 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376246.1 1 NUP37 O36030 Reactome DB_ID: 10870535 UniProt:O36030 UniProt O36030 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10870535 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870535 Reactome R-SPO-376237 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376237.1 1 nup120 NUP160 O43044 Reactome DB_ID: 10870523 UniProt:O43044 nup120 UniProt O43044 1 EQUAL 1436 EQUAL Reactome Database ID Release 82 10870523 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870523 Reactome R-SPO-376253 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376253.1 1 NUP43 O13856 Reactome DB_ID: 10870540 UniProt:O13856 UniProt O13856 1 EQUAL 380 EQUAL Reactome Database ID Release 82 10870540 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870540 Reactome R-SPO-376243 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376243.1 1 nup189 NUP98-5 Q9UTK4 Reactome DB_ID: 10870530 UniProt:Q9UTK4 nup189 UniProt Q9UTK4 1 EQUAL 880 EQUAL Reactome Database ID Release 82 10870530 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870530 Reactome R-SPO-376247 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376247.1 1 nup131 NUP133 Q9P797 Reactome DB_ID: 10870518 UniProt:Q9P797 nup131 UniProt Q9P797 1 EQUAL 1156 EQUAL Reactome Database ID Release 82 10870518 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870518 Reactome R-SPO-376251 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376251.1 1 nup107 NUP107 Q10331 Reactome DB_ID: 10870513 UniProt:Q10331 nup107 UniProt Q10331 1 EQUAL 925 EQUAL Reactome Database ID Release 82 10870513 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870513 Reactome R-SPO-376241 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376241.1 1 sec13 SEC13 O94319 Reactome DB_ID: 10870545 UniProt:O94319 sec13 UniProt O94319 2 EQUAL 322 EQUAL Reactome Database ID Release 82 10870545 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870545 Reactome R-SPO-203981 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-203981.1 1 Reactome Database ID Release 82 10870549 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10870549 Reactome R-SPO-377883 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-377883.1 32 Ghost homologue of AHCTF1 Reactome DB_ID: 10890764 Reactome Database ID Release 82 10890764 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890764 Reactome R-SPO-376244 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-376244.1 16 Converted from EntitySet in Reactome Chromatin Reactome DB_ID: 2537690 Sister Centromere Reactome DB_ID: 1638792 chromosome GENE ONTOLOGY GO:0005694 Reactome Database ID Release 82 1638792 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638792 Reactome R-ALL-1638792 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638792.3 ChEBI 23367 additional information MI MI:0361 Sister Chromatid Sister Chromosomal Arm Reactome DB_ID: 1638790 Reactome Database ID Release 82 1638790 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1638790 Reactome R-ALL-1638790 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-1638790.3 ChEBI 23367 Reactome Database ID Release 82 2537690 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2537690 Reactome R-ALL-2537690 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-2537690.1 1 Reactome Database ID Release 82 10890766 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890766 Reactome R-SPO-9615902 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9615902.1 1 Reactome Database ID Release 82 10890864 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890864 Reactome R-SPO-9618374 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9618374.1 nup184 NUP188 Q9P7M8 Reactome DB_ID: 10890876 UniProt:Q9P7M8 nup184 UniProt Q9P7M8 2 EQUAL 1749 EQUAL Reactome Database ID Release 82 10890876 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890876 Reactome R-SPO-9634172 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634172.1 16 Nup93 complex Reactome DB_ID: 10890874 nup186 NUP205 P78847 Reactome DB_ID: 10890868 UniProt:P78847 nup186 UniProt P78847 2 EQUAL 2012 EQUAL Reactome Database ID Release 82 10890868 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890868 Reactome R-SPO-9634168 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634168.1 1 NUP155 Q9URX8 Reactome DB_ID: 10890866 UniProt:Q9URX8 UniProt Q9URX8 1 EQUAL 1391 EQUAL Reactome Database ID Release 82 10890866 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890866 Reactome R-SPO-9634170 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634170.1 1 mug87 NUP93 O94418 Reactome DB_ID: 10890872 UniProt:O94418 mug87 UniProt O94418 1 EQUAL 819 EQUAL Reactome Database ID Release 82 10890872 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890872 Reactome R-SPO-9634167 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634167.1 1 nup40 NUP35 O13838 Reactome DB_ID: 10890870 UniProt:O13838 nup40 UniProt O13838 1 EQUAL 326 EQUAL Reactome Database ID Release 82 10890870 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890870 Reactome R-SPO-9634171 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634171.1 1 Reactome Database ID Release 82 10890874 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890874 Reactome R-SPO-9634166 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634166.1 32 Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin Reactome DB_ID: 10890878 32 1 16 32 Reactome Database ID Release 82 10890878 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890878 Reactome R-SPO-9634164 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634164.1 Reactome Database ID Release 82 10890880 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10890880 Reactome R-SPO-9634169 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SPO-9634169.1 From studies with Xenopus and human model systems, the transmembrane nucleoporins POM121 and NDC1 recruit the NUP93 complex to nascent nuclear pore complexes (NPCs) due to interaction with the NUP93 complex components NUP155 (Mitchell et al. 2010) and, potentially, NUP35 (Mansfield et al. 2006). This is consistent with order-of-assembly seen in live cell imaging (Dultz et al. 2008). 18316408 Pubmed 2008 Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells Dultz, Elisa Zanin, Esther Wurzenberger, Claudia Braun, Marion Rabut, Gwénaël Sironi, Lucia Ellenberg, Jan J. Cell Biol. 180:857-65 20974814 Pubmed 2010 Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane Mitchell, Jana M Mansfeld, Jörg Capitanio, Juliana Kutay, Ulrike Wozniak, Richard W J. Cell Biol. 191:505-21 16600873 Pubmed 2006 The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells Mansfeld, Jörg Güttinger, Stephan Hawryluk-Gara, Lisa A Panté, Nelly Mall, Moritz Galy, Vincent Haselmann, Uta Mühlhäusser, Petra Wozniak, Richard W Mattaj, Iain W Kutay, Ulrike Antonin, Wolfram Mol. Cell 22:93-103 inferred from electronic annotation EVIDENCE CODE ECO:0000203