BioPAX pathway converted from "Mitochondrial recruitment of Drp1" in the Reactome database. LEFT-TO-RIGHT Mitochondrial recruitment of Drp1 This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a> DNM1L P54861 Reactome DB_ID: 10900713 cytosol GENE ONTOLOGY GO:0005829 UniProt:P54861 Saccharomyces cerevisiae NCBI Taxonomy 4932 UniProt P54861 1 EQUAL 736 EQUAL Reactome Database ID Release 82 10900713 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900713 Reactome R-SCE-351943 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-351943.1 Reactome http://www.reactome.org DNM1L P54861 Reactome DB_ID: 10900715 mitochondrial outer membrane GENE ONTOLOGY GO:0005741 1 EQUAL 736 EQUAL Reactome Database ID Release 82 10900715 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900715 Reactome R-SCE-351942 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-351942.1 Reactome Database ID Release 82 10900717 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900717 Reactome R-SCE-351948 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-351948.1 Adenoviral expression of the BAP31 cleavage product, p20 causes early release of Ca2+ from the ER, concomitant uptake of Ca2+ into mitochondria, and recruitment of Drp1 to the mitochondria (Breckenridge et al., 2003). Drp1 mediates scission of the outer mitochondrial membrane, resulting in dramatic fragmentation and fission of the mitochondrial network. 12668660 Pubmed 2003 Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol Breckenridge, DG Stojanovic, M Marcellus, RC Shore, GC J Cell Biol 160:1115-27 inferred from electronic annotation EVIDENCE CODE ECO:0000203 ACTIVATION Reactome Database ID Release 82 10900718 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900718 YET3 BCAP31(2-164) Q07451 Reactome DB_ID: 10900690 endoplasmic reticulum membrane GENE ONTOLOGY GO:0005789 UniProt:Q07451 YET3 UniProt Q07451 2 EQUAL 164 EQUAL Reactome Database ID Release 82 10900690 Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10900690 Reactome R-SCE-351826 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-SCE-351826.1