BioPAX pathway converted from "CHD1L is recruited to GG-NER site" in the Reactome database.LEFT-TO-RIGHTCHD1L is recruited to GG-NER siteThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Chd1lCHD1LQ9CXF7Reactome DB_ID: 9789920nucleoplasmGENE ONTOLOGYGO:0005654UniProt:Q9CXF7Chd1lMus musculusNCBI Taxonomy10090UniProtQ9CXF71EQUAL897EQUALReactome Database ID Release 759789920Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789920ReactomeR-MMU-56889161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5688916.1Reactomehttp://www.reactome.orgUb:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2Reactome DB_ID: 9790037XpaXPAQ64267Reactome DB_ID: 9789914UniProt:Q64267XpaUniProtQ642672EQUAL273EQUALReactome Database ID Release 759789914Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789914ReactomeR-MMU-674371Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-67437.11Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2Reactome DB_ID: 9790033PAR-PARP1,PAR-PARP2 dimersReactome DB_ID: 9785744Converted from EntitySet in ReactomePAR-PARP1,PAR-PARP2Reactome DB_ID: 9785742Parp1PAR-PARP1P11103Reactome DB_ID: 9785737UniProt:P11103Parp1UniProtP11103L-glutamyl-5-poly(ADP-ribose)MODMOD:003002EQUAL1014EQUALReactome Database ID Release 759785737Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785737ReactomeR-MMU-56517131Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5651713.1Parp2PAR-PARP2O88554Reactome DB_ID: 9785740UniProt:O88554Parp2UniProtO885541EQUAL583EQUALReactome Database ID Release 759785740Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785740ReactomeR-MMU-56517151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5651715.1Reactome Database ID Release 759785742Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785742ReactomeR-MMU-56517121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5651712.12Reactome Database ID Release 759785744Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785744ReactomeR-MMU-56517091Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5651709.11Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDBReactome DB_ID: 9790031Ub:XPC:RAD23:CETN2Reactome DB_ID: 9790029Cetn2CETN2Q9R1K9Reactome DB_ID: 9778964UniProt:Q9R1K9Cetn2UniProtQ9R1K91EQUAL172EQUALReactome Database ID Release 759778964Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9778964ReactomeR-MMU-45704901Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-4570490.11Converted from EntitySet in ReactomeRAD23Reactome DB_ID: 9790022Rad23bRAD23BP54728Reactome DB_ID: 9789621UniProt:P54728Rad23bUniProtP547281EQUAL409EQUALReactome Database ID Release 759789621Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789621ReactomeR-MMU-625901Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-62590.1Rad23aRAD23AP54726Reactome DB_ID: 9789617UniProt:P54726Rad23aUniProtP547261EQUAL363EQUALReactome Database ID Release 759789617Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789617ReactomeR-MMU-56880761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5688076.1Reactome Database ID Release 759790022Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790022ReactomeR-MMU-56881301Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5688130.11Ub:XPCReactome DB_ID: 9790027Converted from EntitySet in ReactomeUbUbiquitinUBIQ_HUMANReactome DB_ID: 9707835Ubiquitin (Pps27a)Reactome DB_ID: 940369UniProt:P62983 Rps27aRps27aUba80Ubcep1SUBUNIT Ribosomal protein S27a is part of the 40S ribosomal subunit.MISCELLANEOUS Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.SIMILARITY In the N-terminal section; belongs to the ubiquitin family.SIMILARITY In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.UniProtP629831EQUAL76EQUALReactome Database ID Release 75940369Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940369ReactomeR-MMU-9403691Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940369.1Ubiquitin (Uba52)Reactome DB_ID: 940378UniProt:P62984 Uba52Uba52Ubcep2SUBUNIT Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).MISCELLANEOUS Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.SIMILARITY In the N-terminal section; belongs to the ubiquitin family.SIMILARITY In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.UniProtP629841EQUAL76EQUALReactome Database ID Release 75940378Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940378ReactomeR-MMU-9403781Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940378.1Ubiquitin (Ubc 1)Reactome DB_ID: 940376UniProt:P0CG50 UbcUbcMISCELLANEOUS Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.MISCELLANEOUS For the sake of clarity sequence features are annotated only for the first chain, and are not repeated for each of the following chains.SIMILARITY Belongs to the ubiquitin family.UniProtP0CG501EQUAL76EQUALReactome Database ID Release 75940376Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940376ReactomeR-MMU-9403761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940376.1Ubiquitin (Ubc 2)Reactome DB_ID: 94037477EQUAL152EQUALReactome Database ID Release 75940374Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940374ReactomeR-MMU-9403741Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940374.1Ubiquitin (Ubc 3)Reactome DB_ID: 940381153EQUAL228EQUALReactome Database ID Release 75940381Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940381ReactomeR-MMU-9403811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940381.1Ubiquitin (Ubb 1)Reactome DB_ID: 940367UniProt:P0CG49 UbbUbbSUBUNIT Interacts with SKP1-KMD2A and SKP1-KMD2B complexes.MISCELLANEOUS Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.MISCELLANEOUS For the sake of clarity sequence features are annotated only for the first chain, and are not repeated for each of the following chains.SIMILARITY Belongs to the ubiquitin family.UniProtP0CG491EQUAL76EQUALReactome Database ID Release 75940367Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940367ReactomeR-MMU-9403671Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940367.1Ubiquitin (Ubb 2)Reactome DB_ID: 94036677EQUAL152EQUALReactome Database ID Release 75940366Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940366ReactomeR-MMU-9403661Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940366.1Ubiquitin (Ubb 3)Reactome DB_ID: 940380153EQUAL228EQUALReactome Database ID Release 75940380Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940380ReactomeR-MMU-9403801Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940380.1Ubiquitin (Ubb 4)Reactome DB_ID: 940385229EQUAL304EQUALReactome Database ID Release 75940385Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=940385ReactomeR-MMU-9403851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-940385.1UbbUBC(305-380)P0CG49Reactome DB_ID: 9707825305EQUAL380EQUALReactome Database ID Release 759707825Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9707825ReactomeR-MMU-9398631Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-939863.1Reactome Database ID Release 759707835Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9707835ReactomeR-MMU-685241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-68524.11XpcUb-XPCP51612Reactome DB_ID: 9790025UniProt:P51612XpcUniProtP51612ubiquitinylated lysineMODMOD:011482EQUAL940EQUALReactome Database ID Release 759790025Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790025ReactomeR-MMU-67829441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-6782944.11Reactome Database ID Release 759790027Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790027ReactomeR-MMU-67829511Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-6782951.11Reactome Database ID Release 759790029Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790029ReactomeR-MMU-67829471Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-6782947.11Distorted dsDNAReactome DB_ID: 5688114Reactome Database ID Release 755688114Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5688114ReactomeR-ALL-56881142Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-5688114.2ChEBI61120additional informationMIMI:03611PAR-UV-DDBReactome DB_ID: 9789929Rbx1E3 ubiquitin-protein ligase RBX1 ecNumber6.3.2.-/ecNumberRBX1_MOUSERbx1Reactome DB_ID: 3247499UniProt:P62878 Rbx1Rbx1FUNCTION E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair (PubMed:22118460). CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (By similarity). The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components (By similarity). As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation (By similarity). Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate (By similarity). Probably also stimulates CDC34 autoubiquitination (By similarity). May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair (By similarity). Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M (By similarity). Involved in the ubiquitination of KEAP1, ENC1 and KLHL41 (By similarity). In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM (By similarity).PATHWAY Protein modification; protein ubiquitination.SUBUNIT Interacts with COPS6. Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1. Part of an E3 ligase complex composed of RBX1, DDB1, DDB2 and CUL4A or CUL4B (PubMed:22118460). Interacts with CAND1 (PubMed:22118460). Interacts with UBE2M (By similarity). Part of a SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Part of a SCF-like complex consisting of CUL7, RBX1, SKP1 and FBXW8. Part of CBC(VHL) complexes with elongin BC complex (ELOB and ELOC), CUL2 or CUL5 and VHL. Part of the CSA complex (DCX(ERCC8) complex), a DCX E3 ubiquitin-protein ligase complex containing ERCC8, RBX1, DDB1 and CUL4A; the CSA complex interacts with RNA polymerase II; upon UV irradiation it interacts with the COP9 signalosome and preferentially with the hyperphosphorylated form of RNA polymerase II (By similarity). Part of multisubunit E3 ubiquitin ligase complexes with elongin BC complex (ELOB and ELOC), CUL2 and MED8; elongin BC complex (ELOB and ELOC), CUL5 and MUF1. Part of multisubunit complexes with elongin BC complex (ELOB and ELOC), elongin A/ELOA or SOCS1 or WSB1 and CUL5. Interacts directly with CUL1 and probably also with CUL2, CUL3, CUL4A, CUL4B, CUL5 and CUL7. Interacts with CDC34. Interacts with GLMN. GLMN competes for the binding site of the E2 ubiquitin-conjugating enzyme CDC34 and disrupts CDC34 binding. Part of a SCF complex consisting of CUL1, RBX1, SKP1 and FBXO2. Part of a SCF complex consisting of CUL1, FBXO3, RBX1 and SKP1; this complex interacts with PML via FBXO3. Component of the SCF(Cyclin F) complex consisting of CUL1, RBX1, SKP1 and CCNF. Identified in a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex together with HINT1 and CDC34 (By similarity). Component of multiple BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes formed of CUL3, RBX1 and a variable BTB domain-containing protein. Part of the BCR(ENC1) complex containing ENC1. Part of the BCR(GAN) complex containing GAN. Part of the BCR(KLHL41) complex containing KLHL41. Part of the BCR(KEAP1) complex containing KEAP1 (By similarity). Interacts with DCUN1D3 (By similarity). Interacts with SESN1 and SESN2 (By similarity). Interacts with NOTCH2 (By similarity). Component of the BCR(KLHL22) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL22 and RBX1 (By similarity).TISSUE SPECIFICITY Widely expressed.DOMAIN The RING-type zinc finger domain is essential for ubiquitin ligase activity (By similarity). It coordinates an additional third zinc ion (PubMed:22118460).SIMILARITY Belongs to the RING-box family.UniProtP628782EQUAL108EQUALReactome Database ID Release 753247499Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3247499ReactomeR-MMU-32474991Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-3247499.11Converted from EntitySet in ReactomeCUL4Reactome DB_ID: 9785796Cul4aCUL4AQ3TCH7Reactome DB_ID: 9785790UniProt:Q3TCH7Cul4aUniProtQ3TCH71EQUAL759EQUALReactome Database ID Release 759785790Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785790ReactomeR-MMU-9760061Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-976006.1Cul4bCUL4BA2A432Reactome DB_ID: 9785794UniProt:A2A432Cul4bUniProtA2A4321EQUAL913EQUALReactome Database ID Release 759785794Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785794ReactomeR-MMU-9759731Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-975973.1Reactome Database ID Release 759785796Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785796ReactomeR-MMU-9760811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-976081.11DDB1:PAR-DDB2Reactome DB_ID: 9789927Ddb2PAR-DDB2Q99J79Reactome DB_ID: 9789925UniProt:Q99J79Ddb2UniProtQ99J791EQUAL427EQUALReactome Database ID Release 759789925Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789925ReactomeR-MMU-56966541Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696654.11Ddb1DDB1Q3U1J4Reactome DB_ID: 9785800UniProt:Q3U1J4Ddb1UniProtQ3U1J41EQUAL1140EQUALReactome Database ID Release 759785800Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9785800ReactomeR-MMU-534891Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-53489.11Reactome Database ID Release 759789927Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789927ReactomeR-MMU-56966801Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696680.11Reactome Database ID Release 759789929Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789929ReactomeR-MMU-56966491Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696649.11Reactome Database ID Release 759790031Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790031ReactomeR-MMU-56966591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696659.11Reactome Database ID Release 759790033Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790033ReactomeR-MMU-56966811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696681.11TFIIH CoreReactome DB_ID: 9789916Gtf2h1GTF2H1Q9DBA9Reactome DB_ID: 9711585UniProt:Q9DBA9Gtf2h1UniProtQ9DBA91EQUAL548EQUALReactome Database ID Release 759711585Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711585ReactomeR-MMU-659121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-65912.11Gtf2h3GTF2H3Q8VD76Reactome DB_ID: 9711573UniProt:Q8VD76Gtf2h3UniProtQ8VD761EQUAL308EQUALReactome Database ID Release 759711573Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711573ReactomeR-MMU-659161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-65916.11Ercc2ERCC2O08811Reactome DB_ID: 9711565UniProt:O08811Ercc2UniProtO088111EQUAL760EQUALReactome Database ID Release 759711565Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711565ReactomeR-MMU-674431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-67443.11Gtf2h2GTF2H2Q9JIB4Reactome DB_ID: 9711577UniProt:Q9JIB4Gtf2h2UniProtQ9JIB41EQUAL395EQUALReactome Database ID Release 759711577Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711577ReactomeR-MMU-659141Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-65914.11Gtf2h5GTF2H5Q8K2X8Reactome DB_ID: 9711589UniProt:Q8K2X8Gtf2h5UniProtQ8K2X81EQUAL71EQUALReactome Database ID Release 759711589Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711589ReactomeR-MMU-56884461Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5688446.11Ercc3ERCC3P49135Reactome DB_ID: 9711569UniProt:P49135Ercc3UniProtP491351EQUAL782EQUALReactome Database ID Release 759711569Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711569ReactomeR-MMU-674391Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-67439.11Gtf2h4GTF2H4O70422Reactome DB_ID: 9711581UniProt:O70422Gtf2h4UniProtO704221EQUAL462EQUALReactome Database ID Release 759711581Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9711581ReactomeR-MMU-659181Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-65918.11Reactome Database ID Release 759789916Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9789916ReactomeR-MMU-56896241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5689624.11Reactome Database ID Release 759790037Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790037ReactomeR-MMU-56893001Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5689300.1Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1LReactome DB_ID: 979083211Reactome Database ID Release 759790832Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9790832ReactomeR-MMU-56966521Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696652.1Reactome Database ID Release 759792511Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9792511ReactomeR-MMU-56966701Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-MMU-5696670.1A chromatin remodeling enzyme CHD1L (ALC1) is recruited to DNA damage sites through interaction with PARylated PARP1 (or possibly PARP2) (Ahel et al. 2009) or PARylated DDB2 (Pines et al. 2012). CHD1L catalyzes PARP-stimulated nucleosome sliding and is needed for efficient PARP-dependent DNA repair (Ahel et al. 2009). CHD1L depletion or PARP inhibition impair global genomic nucleotide excision repair (GG-NER) of UV-induced DNA damage (Pines et al. 2012).19661379Pubmed2009Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1Ahel, DraganaHorejsí, ZuzanaWiechens, NicolaPolo, Sophie EGarcia-Wilson, ElisaAhel, IvanFlynn, HelenSkehel, MarkWest, Stephen CJackson, Stephen POwen-Hughes, TomBoulton, Simon JScience 325:1240-323045548Pubmed2012PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1Pines, AlexVrouwe, Mischa GMarteijn, Jurgen ATypas, DimitrisLuijsterburg, Martijn SCansoy, MedineHensbergen, PaulDeelder, Andréde Groot, AntonMatsumoto, SyotaSugasawa, KaoruThoma, NicolasVermeulen, WimVrieling, HarryMullenders, LeonJ. Cell Biol. 199:235-49inferred from electronic annotationEVIDENCE CODEECO:0000203