BioPAX pathway converted from "G alpha (q) signalling events" in the Reactome database.G alpha (q) signalling eventsThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>LEFT-TO-RIGHTLiganded Gq/11-activating GPCRs act as GEFs for Gq/11This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>GTPGuanosine 5'-triphosphateReactome DB_ID: 29438cytosolGENE ONTOLOGYGO:0005829GTP [ChEBI:15996]GTPGuanosine 5'-triphosphateChEBICHEBI:15996Reactome Database ID Release 7529438Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29438ReactomeR-ALL-294383Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-29438.3Reactomehttp://www.reactome.orgCOMPOUNDC00044additional informationMIMI:0361Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive)Reactome DB_ID: 9847953plasma membraneGENE ONTOLOGYGO:0005886Heterotrimeric G-protein Gq/11 (inactive)Reactome DB_ID: 9830154G-protein beta-gamma complexReactome DB_ID: 9829597Converted from EntitySet in ReactomeG-protein gamma subunitReactome DB_ID: 9829573Gng3GNG3G3V8K2Reactome DB_ID: 9829523UniProt:G3V8K2Gng3Rattus norvegicusNCBI Taxonomy10116UniProtG3V8K21EQUAL72EQUALReactome Database ID Release 759829523Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829523ReactomeR-RNO-1643761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164376.1Gng4GNG4M0R809Reactome DB_ID: 9829527UniProt:M0R809Gng4UniProtM0R8091EQUAL72EQUALReactome Database ID Release 759829527Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829527ReactomeR-RNO-1643501Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164350.1Converted from EntitySet in ReactomeHomologues of GNG5Reactome DB_ID: 9829538GNG5F2Z3T8Reactome DB_ID: 9829531UniProt:F2Z3T8UniProtF2Z3T82EQUAL65EQUALReactome Database ID Release 759829531Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829531ReactomeR-RNO-1643831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164383.1Gng5GNG5P63219Reactome DB_ID: 9829536UniProt:P63219Gng5UniProtP632192EQUAL65EQUALReactome Database ID Release 759829536Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829536ReactomeR-RNO-164383-21Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164383-2.1Reactome Database ID Release 759829538Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829538ReactomeR-RNO-164383-31Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164383-3.1Gng7GNG7P43425Reactome DB_ID: 9829542UniProt:P43425Gng7UniProtP434252EQUAL65EQUALReactome Database ID Release 759829542Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829542ReactomeR-RNO-1643251Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164325.1Gng8GNG8P63077Reactome DB_ID: 9829546UniProt:P63077Gng8UniProtP630771EQUAL67EQUALReactome Database ID Release 759829546Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829546ReactomeR-RNO-1643711Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164371.1Gngt2GNGT2D3ZLD6Reactome DB_ID: 9829550UniProt:D3ZLD6Gngt2UniProtD3ZLD61EQUAL66EQUALReactome Database ID Release 759829550Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829550ReactomeR-RNO-1674401Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167440.1Gng10GNG10Q3KRE3Reactome DB_ID: 9829554UniProt:Q3KRE3Gng10UniProtQ3KRE31EQUAL65EQUALReactome Database ID Release 759829554Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829554ReactomeR-RNO-1643441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164344.1Gng11GNG11P61954Reactome DB_ID: 9829559UniProt:P61954Gng11UniProtP619541EQUAL70EQUALReactome Database ID Release 759829559Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829559ReactomeR-RNO-1643291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164329.1Gng12GNG12G3V6P8Reactome DB_ID: 9829563UniProt:G3V6P8Gng12UniProtG3V6P82EQUAL69EQUALReactome Database ID Release 759829563Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829563ReactomeR-RNO-1643671Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164367.1Gng13GNG13G3V8Y0Reactome DB_ID: 9829567UniProt:G3V8Y0Gng13UniProtG3V8Y01EQUAL64EQUALReactome Database ID Release 759829567Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829567ReactomeR-RNO-1643461Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-164346.1Gngt1GNGT1D4AAI1Reactome DB_ID: 9829571UniProt:D4AAI1Gngt1UniProtD4AAI12EQUAL71EQUALReactome Database ID Release 759829571Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829571ReactomeR-RNO-1674281Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167428.1Reactome Database ID Release 759829573Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829573ReactomeR-RNO-1674421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167442.11Converted from EntitySet in ReactomeGNBG-protein beta subunitReactome DB_ID: 9829595Gnb1GNB1P54311Reactome DB_ID: 9829577UniProt:P54311Gnb1UniProtP543112EQUAL340EQUALReactome Database ID Release 759829577Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829577ReactomeR-RNO-68144121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814412.1Gnb2GNB2P54313Reactome DB_ID: 9829581UniProt:P54313Gnb2UniProtP543132EQUAL340EQUALReactome Database ID Release 759829581Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829581ReactomeR-RNO-68144211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814421.1Gnb3GNB3P52287Reactome DB_ID: 9829585UniProt:P52287Gnb3UniProtP522871EQUAL340EQUALReactome Database ID Release 759829585Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829585ReactomeR-RNO-68144141Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814414.1Gnb4GNB4O35353Reactome DB_ID: 9829589UniProt:O35353Gnb4UniProtO353532EQUAL340EQUALReactome Database ID Release 759829589Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829589ReactomeR-RNO-68144171Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814417.1Gnb5GNB5P62882Reactome DB_ID: 9829593UniProt:P62882Gnb5UniProtP628821EQUAL395EQUALReactome Database ID Release 759829593Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829593ReactomeR-RNO-68144161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814416.1Reactome Database ID Release 759829595Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829595ReactomeR-RNO-68144131Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-6814413.11Reactome Database ID Release 759829597Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829597ReactomeR-RNO-1674341Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167434.11G-protein alpha (q/11):GDPReactome DB_ID: 9830152GDPGuanosine 5'-diphosphateGuanosine diphosphateReactome DB_ID: 114549GDP [ChEBI:17552]GDPGuanosine 5'-diphosphateGuanosine diphosphateChEBICHEBI:17552Reactome Database ID Release 75114549Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114549ReactomeR-ALL-1145492Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114549.2COMPOUNDC000351Converted from EntitySet in ReactomeG-protein alpha (q/11)Reactome DB_ID: 9830150Gna11GNA11Q9JID2Reactome DB_ID: 9830136UniProt:Q9JID2Gna11UniProtQ9JID21EQUAL359EQUALReactome Database ID Release 759830136Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830136ReactomeR-RNO-1674461Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167446.1Gna14GNA14Q5EAP4Reactome DB_ID: 9830140UniProt:Q5EAP4Gna14UniProtQ5EAP41EQUAL355EQUALReactome Database ID Release 759830140Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830140ReactomeR-RNO-1674531Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167453.1Gna15GNA15O88302Reactome DB_ID: 9830144UniProt:O88302Gna15UniProtO883021EQUAL374EQUALReactome Database ID Release 759830144Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830144ReactomeR-RNO-1674501Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-167450.1GnaqGNAQP82471Reactome DB_ID: 9830148UniProt:P82471GnaqUniProtP824711EQUAL359EQUALReactome Database ID Release 759830148Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830148ReactomeR-RNO-554531Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-55453.1Reactome Database ID Release 759830150Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830150ReactomeR-RNO-3748481Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374848.11Reactome Database ID Release 759830152Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830152ReactomeR-RNO-1145561Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-114556.11Reactome Database ID Release 759830154Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830154ReactomeR-RNO-1145571Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-114557.11Converted from EntitySet in ReactomeLigand:GPCR complexes that activate Gq/11Reactome DB_ID: 9847951AGTR1:AGT(34-41)Reactome DB_ID: 9846285Agtr1AGTR1P25095Reactome DB_ID: 9846279UniProt:P25095Agtr1UniProtP250951EQUAL359EQUALReactome Database ID Release 759846279Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846279ReactomeR-RNO-3742471Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374247.11AgtAGT(34-41)P01015Reactome DB_ID: 9846283extracellular regionGENE ONTOLOGYGO:0005576UniProt:P01015AgtUniProtP0101534EQUAL41EQUALReactome Database ID Release 759846283Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846283ReactomeR-RNO-3741871Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374187.11Reactome Database ID Release 759846285Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846285ReactomeR-RNO-3898761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389876.1Bombesin-like receptor:bombesin-like peptideReactome DB_ID: 9846958Converted from EntitySet in ReactomeBombesin-like receptorReactome DB_ID: 9846956GrprGRPRP52500Reactome DB_ID: 9846946UniProt:P52500GrprUniProtP525001EQUAL384EQUALReactome Database ID Release 759846946Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846946ReactomeR-RNO-3753631Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375363.1NmbrNMBRP24053Reactome DB_ID: 9846950UniProt:P24053NmbrUniProtP240531EQUAL390EQUALReactome Database ID Release 759846950Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846950ReactomeR-RNO-3753571Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375357.1Brs3BRS3Q8K418Reactome DB_ID: 9846954UniProt:Q8K418Brs3UniProtQ8K4181EQUAL399EQUALReactome Database ID Release 759846954Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846954ReactomeR-RNO-9476941Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947694.1Reactome Database ID Release 759846956Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846956ReactomeR-RNO-3753621Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375362.11Converted from EntitySet in ReactomeBombesin-like peptideReactome DB_ID: 9846942GrpGRP(24-50)P24393Reactome DB_ID: 9846936UniProt:P24393GrpUniProtP2439324EQUAL50EQUALReactome Database ID Release 759846936Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846936ReactomeR-RNO-3753581Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375358.1NmbNMB(47-56)D4A1W6Reactome DB_ID: 9846940UniProt:D4A1W6NmbUniProtD4A1W647EQUAL56EQUALReactome Database ID Release 759846940Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846940ReactomeR-RNO-3753611Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375361.1Reactome Database ID Release 759846942Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846942ReactomeR-RNO-3753601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375360.11Reactome Database ID Release 759846958Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846958ReactomeR-RNO-3753591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-375359.1Bradykinin receptor:BradykininReactome DB_ID: 9847376Converted from EntitySet in ReactomeBDKRB1,BDKRB2Bradykinin receptorReactome DB_ID: 9847374Bdkrb1BDKRB1P97583Reactome DB_ID: 9847368UniProt:P97583Bdkrb1UniProtP975831EQUAL353EQUALReactome Database ID Release 759847368Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847368ReactomeR-RNO-3742571Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374257.1Bdkrb2BDKRB2P25023Reactome DB_ID: 9847372UniProt:P25023Bdkrb2UniProtP250231EQUAL391EQUALReactome Database ID Release 759847372Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847372ReactomeR-RNO-3742551Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374255.1Reactome Database ID Release 759847374Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847374ReactomeR-RNO-3743231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374323.11Ghost homologue of BradykininReactome DB_ID: 9847364Reactome Database ID Release 759847364Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847364ReactomeR-RNO-1583441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-158344.11Reactome Database ID Release 759847376Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847376ReactomeR-RNO-3743211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-374321.1CHRM1,3,5:AcChoReactome DB_ID: 9847392Converted from EntitySet in ReactomeCHRM1,3,5Reactome DB_ID: 9847390Chrm1CHRM1P08482Reactome DB_ID: 9847380UniProt:P08482Chrm1UniProtP084821EQUAL460EQUALReactome Database ID Release 759847380Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847380ReactomeR-RNO-3906281Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390628.1Chrm5CHRM5P08911Reactome DB_ID: 9847384UniProt:P08911Chrm5UniProtP089111EQUAL532EQUALReactome Database ID Release 759847384Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847384ReactomeR-RNO-3906781Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390678.1Chrm3CHRM3P08483Reactome DB_ID: 9847388UniProt:P08483Chrm3UniProtP084831EQUAL590EQUALReactome Database ID Release 759847388Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847388ReactomeR-RNO-3999941Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-399994.1Reactome Database ID Release 759847390Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847390ReactomeR-RNO-3906601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390660.11AcChoO-acetylcholineacetylcholineReactome DB_ID: 372533acetylcholine [ChEBI:15355]acetylcholineChEBICHEBI:15355Reactome Database ID Release 75372533Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=372533ReactomeR-ALL-3725333Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-372533.31Reactome Database ID Release 759847392Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847392ReactomeR-RNO-3906761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390676.1ADRA1A,B,D:ADR,NAdReactome DB_ID: 9847408Converted from EntitySet in ReactomeADRA1A,B,DAlpha-1 adrenoceptorReactome DB_ID: 9847406Adra1aADRA1AP43140Reactome DB_ID: 9847396UniProt:P43140Adra1aUniProtP431401EQUAL466EQUALReactome Database ID Release 759847396Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847396ReactomeR-RNO-3906691Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390669.1Adra1bADRA1BP15823Reactome DB_ID: 9847400UniProt:P15823Adra1bUniProtP158231EQUAL520EQUALReactome Database ID Release 759847400Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847400ReactomeR-RNO-3906611Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390661.1Adra1dADRA1DP23944Reactome DB_ID: 9847404UniProt:P23944Adra1dUniProtP239441EQUAL572EQUALReactome Database ID Release 759847404Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847404ReactomeR-RNO-3906801Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390680.1Reactome Database ID Release 759847406Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847406ReactomeR-RNO-3906841Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390684.11Converted from EntitySet in ReactomeADR, NAdCatecholamineadrenaline or noradrenalineReactome DB_ID: 390627ADRAdrenaline(R)-adrenalineEpinephrineReactome DB_ID: 390625(R)-adrenaline [ChEBI:28918](R)-adrenalineChEBICHEBI:28918Reactome Database ID Release 75390625Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390625ReactomeR-ALL-3906253Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-390625.3COMPOUNDC00788NAdNoradrenaline(R)-noradrenalineNorepinephrineReactome DB_ID: 374935(R)-noradrenaline [ChEBI:18357](R)-noradrenalineChEBICHEBI:18357Reactome Database ID Release 75374935Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=374935ReactomeR-ALL-3749353Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-374935.3COMPOUNDC00547Reactome Database ID Release 75390627Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390627ReactomeR-ALL-3906272Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-390627.21Reactome Database ID Release 759847408Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847408ReactomeR-RNO-3906331Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390633.1HRH1:HistReactome DB_ID: 9847414Hrh1HRH1P31390Reactome DB_ID: 9847412UniProt:P31390Hrh1UniProtP313901EQUAL487EQUALReactome Database ID Release 759847412Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847412ReactomeR-RNO-3909081Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390908.11HisthistamineReactome DB_ID: 390899histamine [ChEBI:18295]histamineChEBICHEBI:18295Reactome Database ID Release 75390899Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390899ReactomeR-ALL-3908993Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-390899.3COMPOUNDC003881Reactome Database ID Release 759847414Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847414ReactomeR-RNO-3908851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390885.1HTR2A-C:5HTReactome DB_ID: 9847430Converted from EntitySet in ReactomeHTR2A-C5-HT2 receptorReactome DB_ID: 9847428Htr2aHTR2AP14842Reactome DB_ID: 9847418UniProt:P14842Htr2aUniProtP148421EQUAL471EQUALReactome Database ID Release 759847418Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847418ReactomeR-RNO-3909471Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390947.1Htr2bHTR2BP30994Reactome DB_ID: 9847422UniProt:P30994Htr2bUniProtP309941EQUAL481EQUALReactome Database ID Release 759847422Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847422ReactomeR-RNO-3909671Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390967.1Htr2cHTR2CP08909Reactome DB_ID: 9847426UniProt:P08909Htr2cUniProtP0890933EQUAL458EQUALReactome Database ID Release 759847426Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847426ReactomeR-RNO-3909651Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390965.1Reactome Database ID Release 759847428Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847428ReactomeR-RNO-3910301Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391030.115HT5-Hydroxytryptamineserotonin3-(2-Aminoethyl)-1H-indol-5-olEnteramineReactome DB_ID: 114523serotonin [ChEBI:28790]serotoninChEBICHEBI:28790Reactome Database ID Release 75114523Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114523ReactomeR-ALL-1145233Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114523.3COMPOUNDC007801Reactome Database ID Release 759847430Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847430ReactomeR-RNO-3909511Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-390951.1GnRH receptor:GNRH ligandsReactome DB_ID: 9847441GnrhrGNRHRP30969Reactome DB_ID: 9847434UniProt:P30969GnrhrUniProtP309691EQUAL328EQUALReactome Database ID Release 759847434Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847434ReactomeR-RNO-3913701Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391370.11Gnrh1GNRH1(24-33)P07490Reactome DB_ID: 9847439UniProt:P07490Gnrh1UniProtP0749024EQUAL33EQUALReactome Database ID Release 759847439Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847439ReactomeR-RNO-8739341Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-873934.11Reactome Database ID Release 759847441Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847441ReactomeR-RNO-3913791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391379.1AVPR1A,B:AVP(20-28)Reactome DB_ID: 9847458Converted from EntitySet in ReactomeAVPR1A,BVasopressin receptor type 1Reactome DB_ID: 9847452Avpr1aAVPR1AP30560Reactome DB_ID: 9847445UniProt:P30560Avpr1aUniProtP305601EQUAL418EQUALReactome Database ID Release 759847445Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847445ReactomeR-RNO-3884841Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388484.1Avpr1bAVPR1BP48974Reactome DB_ID: 9847450UniProt:P48974Avpr1bUniProtP489741EQUAL424EQUALReactome Database ID Release 759847450Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847450ReactomeR-RNO-3884711Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388471.1Reactome Database ID Release 759847452Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847452ReactomeR-RNO-3884581Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388458.11AvpAVP(20-28)P01186Reactome DB_ID: 9847456UniProt:P01186AvpUniProtP0118620EQUAL28EQUALReactome Database ID Release 759847456Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847456ReactomeR-RNO-3884741Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388474.11Reactome Database ID Release 759847458Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847458ReactomeR-RNO-3885021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388502.1P2RY1:ADPReactome DB_ID: 9847464P2ry1P2RY1P49651Reactome DB_ID: 9847462UniProt:P49651P2ry1UniProtP496511EQUAL373EQUALReactome Database ID Release 759847462Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847462ReactomeR-RNO-3919561Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391956.11ADPAdenosine 5'-diphosphateADP(3-)Reactome DB_ID: 114564ADP(3-) [ChEBI:456216]ADP(3-)ADP5&apos;-O-[(phosphonatooxy)phosphinato]adenosineADP trianionChEBICHEBI:456216Reactome Database ID Release 75114564Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114564ReactomeR-ALL-1145644Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114564.4COMPOUNDC000081Reactome Database ID Release 759847464Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847464ReactomeR-RNO-4179201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417920.1P2RY2:ATPReactome DB_ID: 9847470Converted from EntitySet in ReactomeATP,UTPReactome DB_ID: 511955ATPAdenosine 5'-triphosphateATP(4-)Reactome DB_ID: 114570ATP(4-) [ChEBI:30616]ATP(4-)ATPatpAdenosine 5'-triphosphateChEBICHEBI:30616Reactome Database ID Release 75114570Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114570ReactomeR-ALL-1145703Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114570.3COMPOUNDC00002UTPuridine 5'-triphosphateUridine triphosphateReactome DB_ID: 417877UTP [ChEBI:15713]UTPuridine 5'-triphosphateUridine triphosphateChEBICHEBI:15713Reactome Database ID Release 75417877Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=417877ReactomeR-ALL-4178772Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-417877.2COMPOUNDC00075Reactome Database ID Release 75511955Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=511955ReactomeR-ALL-5119552Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-511955.21P2ry2P2RY2P41232Reactome DB_ID: 9847468UniProt:P41232P2ry2UniProtP412321EQUAL377EQUALReactome Database ID Release 759847468Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847468ReactomeR-RNO-4179231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417923.11Reactome Database ID Release 759847470Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847470ReactomeR-RNO-4178661Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417866.1P2RY5:LPAReactome DB_ID: 9847476Lpar6LPAR6Q4G072Reactome DB_ID: 9847474UniProt:Q4G072Lpar6UniProtQ4G0721EQUAL344EQUALReactome Database ID Release 759847474Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847474ReactomeR-RNO-4179131Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417913.11LPALysophosphatidic acid1-octadec-9-enoylglycero-3-phosphateReactome DB_ID: 4178911-octadec-9-enoylglycero-3-phosphate [ChEBI:52288]1-octadec-9-enoylglycero-3-phosphateChEBICHEBI:52288Reactome Database ID Release 75417891Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=417891ReactomeR-ALL-4178913Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-417891.31Reactome Database ID Release 759847476Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847476ReactomeR-RNO-4178871Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417887.1P2RY6:UDPReactome DB_ID: 9847482P2ry6P2RY6Q63371Reactome DB_ID: 9847480UniProt:Q63371P2ry6UniProtQ633711EQUAL328EQUALReactome Database ID Release 759847480Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847480ReactomeR-RNO-4179241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417924.11UDPuridine 5'-diphosphateReactome DB_ID: 417888UDP [ChEBI:17659]UDPChEBICHEBI:17659Reactome Database ID Release 75417888Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=417888ReactomeR-ALL-4178882Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-417888.2COMPOUNDC000151Reactome Database ID Release 759847482Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847482ReactomeR-RNO-4178681Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-417868.1P2RY9:LPAReactome DB_ID: 98474881Lpar4LPAR4D3ZHA3Reactome DB_ID: 9847486UniProt:D3ZHA3Lpar4UniProtD3ZHA31EQUAL370EQUALReactome Database ID Release 759847486Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847486ReactomeR-RNO-4180201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418020.11Reactome Database ID Release 759847488Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847488ReactomeR-RNO-4180231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418023.1P2RY10:LPAReactome DB_ID: 98474941P2ry10P2RY10B5DF87Reactome DB_ID: 9847492UniProt:B5DF87P2ry10UniProtB5DF871EQUAL339EQUALReactome Database ID Release 759847492Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847492ReactomeR-RNO-4180211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418021.11Reactome Database ID Release 759847494Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847494ReactomeR-RNO-4180191Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418019.1Melanospin:photonReactome DB_ID: 9847500photoreceptor disc membraneGENE ONTOLOGYGO:0097381Opn4OPN4Q8R456Reactome DB_ID: 9847498UniProt:Q8R456Opn4UniProtQ8R4561EQUAL478EQUALReactome Database ID Release 759847498Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847498ReactomeR-RNO-3918251Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391825.11PhotonReactome DB_ID: 419777photon [ChEBI:30212]photonhnuLichtquantLightgammalight quantumfotonChEBICHEBI:30212Reactome Database ID Release 75419777Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=419777ReactomeR-ALL-4197772Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-419777.21Reactome Database ID Release 759847500Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847500ReactomeR-RNO-4198421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419842.1GCGR:GCG(53-81)Reactome DB_ID: 9832832Q924T9Cysltr2CYSLTR2Reactome DB_ID: 9832830UniProt:Q924T9Cysltr2UniProtQ924T91EQUAL346EQUALReactome Database ID Release 759832830Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9832830ReactomeR-RNO-4163991Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416399.11GcgGCG(53-81)P06883Reactome DB_ID: 9832824UniProt:P06883 GcgGcgFUNCTION Oxyntomodulin significantly reduces food intake.TISSUE SPECIFICITY Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract.INDUCTION Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. GLP-1 and GLP-2 are induced in response to nutrient ingestion.PTM Proglucagon is post-translationally processed in a tissue-specific manner in pancreatic A cells and intestinal L cells. In pancreatic A cells, the major bioactive hormone is glucagon cleaved by PCSK2/PC2. In the intestinal L cells PCSK1/PC1 liberates GLP-1, GLP-2, glicentin and oxyntomodulin. GLP-1 is further N-terminally truncated by post-translational processing in the intestinal L cells resulting in GLP-1(7-37) GLP-1-(7-36)amide. The C-terminal amidation is neither important for the metabolism of GLP-1 nor for its effects on the endocrine pancreas.SIMILARITY Belongs to the glucagon family.UniProtP0688353EQUAL81EQUALReactome Database ID Release 759832824Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9832824ReactomeR-RNO-1636261Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-163626.11Reactome Database ID Release 759832832Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9832832ReactomeR-RNO-1636271Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-163627.1CASR:Ca2+Reactome DB_ID: 9847506CasrCASRP48442Reactome DB_ID: 9847504UniProt:P48442CasrUniProtP4844220EQUAL1078EQUALReactome Database ID Release 759847504Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847504ReactomeR-RNO-4207191Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420719.11Ca2+Calciumcalcium(2+)Reactome DB_ID: 74112calcium(2+) [ChEBI:29108]calcium(2+)ChEBICHEBI:29108Reactome Database ID Release 7574112Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=74112ReactomeR-ALL-741124Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-74112.4COMPOUNDC000761Reactome Database ID Release 759847506Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847506ReactomeR-RNO-4207431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420743.1TBXA2R:TXA2Reactome DB_ID: 9847512TXA2(5Z,13E)-(15S)-9alpha,11alpha-Epoxy-15-hydroxythromboxa-5,13-dienoatethromboxane A2(5Z,9alpha,11alpha,13E,15S)-9,11-Epoxy-15-hydroxythromboxa-5,13-dien-1-oic acidReactome DB_ID: 391932thromboxane A2 [ChEBI:15627]thromboxane A2ChEBICHEBI:15627Reactome Database ID Release 75391932Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=391932ReactomeR-ALL-3919323Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-391932.3COMPOUNDC021981Tbxa2rTBXA2RP34978Reactome DB_ID: 9847510UniProt:P34978Tbxa2rUniProtP349781EQUAL343EQUALReactome Database ID Release 759847510Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847510ReactomeR-RNO-3918371Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391837.11Reactome Database ID Release 759847512Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847512ReactomeR-RNO-3919251Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391925.1CYSLTR1:LTC4,LTD4,LTE4Reactome DB_ID: 9847518Q924T8Cysltr1CYSLTR1Reactome DB_ID: 9847516UniProt:Q924T8Cysltr1UniProtQ924T81EQUAL337EQUALReactome Database ID Release 759847516Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847516ReactomeR-RNO-4164181Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416418.11Converted from EntitySet in ReactomeLTC4,LTD4,LTE4Cysteinyl leukotrienesReactome DB_ID: 416372LTC4leukotriene C4Reactome DB_ID: 266013leukotriene C4 [ChEBI:16978]leukotriene C4ChEBICHEBI:16978Reactome Database ID Release 75266013Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=266013ReactomeR-ALL-2660133Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-266013.3COMPOUNDC02166LTD4leukotriene D4Reactome DB_ID: 266074leukotriene D4 [ChEBI:28666]leukotriene D4ChEBICHEBI:28666Reactome Database ID Release 75266074Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=266074ReactomeR-ALL-2660743Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-266074.3COMPOUNDC05951LTE4leukotriene E4Reactome DB_ID: 266033leukotriene E4 [ChEBI:15650]leukotriene E4ChEBICHEBI:15650Reactome Database ID Release 75266033Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=266033ReactomeR-ALL-2660333Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-266033.3COMPOUNDC05952Reactome Database ID Release 75416372Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=416372ReactomeR-ALL-4163722Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-416372.21Reactome Database ID Release 759847518Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847518ReactomeR-RNO-96904441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9690444.1CYSLTR2:LTC4,LTD4,LTE4Reactome DB_ID: 984752011Reactome Database ID Release 759847520Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847520ReactomeR-RNO-4164231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416423.1CCKAR,CCKBR:CCKReactome DB_ID: 9847536CckCCKP01355Reactome DB_ID: 9847524UniProt:P01355CckUniProtP0135521EQUAL115EQUALReactome Database ID Release 759847524Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847524ReactomeR-RNO-3885391Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388539.11Converted from EntitySet in ReactomeCCKAR,CCKBRCholecystokinin receptorsReactome DB_ID: 9847534CckarCCKARP30551Reactome DB_ID: 9847528UniProt:P30551CckarUniProtP305511EQUAL428EQUALReactome Database ID Release 759847528Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847528ReactomeR-RNO-3885171Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388517.1CckbrCCKBRP30553Reactome DB_ID: 9847532UniProt:P30553CckbrUniProtP305531EQUAL447EQUALReactome Database ID Release 759847532Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847532ReactomeR-RNO-3885151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388515.1Reactome Database ID Release 759847534Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847534ReactomeR-RNO-3885181Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388518.11Reactome Database ID Release 759847536Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847536ReactomeR-RNO-3885321Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388532.1GPRC6A receptor:GPRC6A ligandsReactome DB_ID: 9847542Converted from EntitySet in ReactomeGPRC6A ligandsReactome DB_ID: 420706Converted from EntitySet in ReactomeBasic L-amino acidsReactome DB_ID: 420746L-Arg(S)-2-Amino-5-guanidinovaleric acidL-argininium(1+)L-arginineReactome DB_ID: 351977L-argininium(1+) [ChEBI:32682]L-argininium(1+)NC(=[NH2+])NCCC[C@H]([NH3+])C([O-])=OInChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1/t4-/m0/s1ODKSFYDXXFIFQN-BYPYZUCNSA-OL-argininiumL-arginine monocationC6H15N4O2(2S)-2-ammonio-5-guanidiniopentanoateL-arginine175.20906ChEBICHEBI:32682Reactome Database ID Release 75351977Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351977ReactomeR-ALL-3519774Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-351977.4COMPOUNDC00062L-LysLysine acidL-lysinium(1+)L-lysine2,6-diaminohexanoic acidReactome DB_ID: 351991L-lysinium(1+) [ChEBI:32551]L-lysinium(1+)147.19558InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m0/s1L-lysine monocationL-lysineC6H15N2O2L-lysinium[NH3+]CCCC[C@H]([NH3+])C([O-])=O(2S)-2,6-diammoniohexanoateKDXKERNSBIXSRK-YFKPBYRVSA-OChEBICHEBI:32551Reactome Database ID Release 75351991Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351991ReactomeR-ALL-3519914Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-351991.4COMPOUNDC00047L-Orn(S)-2,5-diaminovaleric acidL-ornithine(S)-2,5-Diaminopentanoic acid(S)-2,5-DiaminopentanoateReactome DB_ID: 375800L-ornithine [ChEBI:15729]L-ornithineChEBICHEBI:15729Reactome Database ID Release 75375800Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=375800ReactomeR-ALL-3758003Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-375800.3COMPOUNDC00077Reactome Database ID Release 75420746Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=420746ReactomeR-ALL-4207461Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-420746.1Reactome Database ID Release 75420706Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=420706ReactomeR-ALL-4207061Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-420706.11Gprc6aGPRC6AQ70VB1Reactome DB_ID: 9847540UniProt:Q70VB1Gprc6aUniProtQ70VB119EQUAL926EQUALReactome Database ID Release 759847540Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847540ReactomeR-RNO-4207261Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420726.11Reactome Database ID Release 759847542Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847542ReactomeR-RNO-4207221Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420722.1EDNRA,EDNRB:EndothelinReactome DB_ID: 9847568Converted from EntitySet in ReactomeEndothelinReactome DB_ID: 9847556Edn1EDN1P22388Reactome DB_ID: 9847546UniProt:P22388Edn1UniProtP2238853EQUAL73EQUALReactome Database ID Release 759847546Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847546ReactomeR-RNO-3885451Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388545.1Edn2EDN2P23943Reactome DB_ID: 9847550UniProt:P23943Edn2UniProtP2394349EQUAL69EQUALReactome Database ID Release 759847550Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847550ReactomeR-RNO-3885421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388542.1Edn3EDN3(97-117)P13207Reactome DB_ID: 9847554UniProt:P13207Edn3UniProtP1320797EQUAL117EQUALReactome Database ID Release 759847554Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847554ReactomeR-RNO-3885431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388543.1Reactome Database ID Release 759847556Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847556ReactomeR-RNO-3885441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388544.11Converted from EntitySet in ReactomeEDNRA,EDNRBEndothelin receptorsReactome DB_ID: 9847566EdnraEDNRAP26684Reactome DB_ID: 9847560UniProt:P26684EdnraUniProtP2668421EQUAL427EQUALReactome Database ID Release 759847560Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847560ReactomeR-RNO-3885491Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388549.1EdnrbEDNRBP21451Reactome DB_ID: 9847564UniProt:P21451EdnrbUniProtP2145127EQUAL442EQUALReactome Database ID Release 759847564Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847564ReactomeR-RNO-3885501Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388550.1Reactome Database ID Release 759847566Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847566ReactomeR-RNO-3885471Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388547.11Reactome Database ID Release 759847568Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847568ReactomeR-RNO-3885461Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388546.1FPR2:FPR2 ligandsReactome DB_ID: 9847590Fpr2FPR2F1M670Reactome DB_ID: 9847572UniProt:F1M670Fpr2UniProtF1M6701EQUAL351EQUALReactome Database ID Release 759847572Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847572ReactomeR-RNO-4164081Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416408.11Converted from EntitySet in ReactomeFPR2 ligandsFPRL1 ligandsReactome DB_ID: 9847588LXA4lipoxin A4Reactome DB_ID: 416384lipoxin A4 [ChEBI:6498]lipoxin A4ChEBICHEBI:6498Reactome Database ID Release 75416384Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=416384ReactomeR-ALL-4163843Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-416384.3Anxa1ANXA1P07150Reactome DB_ID: 9847576UniProt:P07150Anxa1UniProtP071502EQUAL346EQUALReactome Database ID Release 759847576Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847576ReactomeR-RNO-4445391Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444539.1Converted from EntitySet in ReactomeHomologues of CCL23-2Reactome DB_ID: 9847586Ccl9CCL23-2Q5FVN3Reactome DB_ID: 9847580UniProt:Q5FVN3Ccl9UniProtQ5FVN346EQUAL137EQUALReactome Database ID Release 759847580Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847580ReactomeR-RNO-4445641Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444564.1Ccl6CCL23-2Q68FP3Reactome DB_ID: 9847584UniProt:Q68FP3Ccl6UniProtQ68FP346EQUAL137EQUALReactome Database ID Release 759847584Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847584ReactomeR-RNO-444564-21Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444564-2.1Reactome Database ID Release 759847586Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847586ReactomeR-RNO-444564-31Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444564-3.1AppAPP(672-713)P08592Reactome DB_ID: 9834323UniProt:P08592AppUniProtP08592672EQUAL713EQUALReactome Database ID Release 759834323Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9834323ReactomeR-RNO-8793401Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-879340.1Reactome Database ID Release 759847588Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847588ReactomeR-RNO-4444721Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444472.11Reactome Database ID Release 759847590Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847590ReactomeR-RNO-4164591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416459.1GPR17:UDPReactome DB_ID: 98475961Gpr17GPR17Q09QM4Reactome DB_ID: 9847594UniProt:Q09QM4Gpr17UniProtQ09QM41EQUAL367EQUALReactome Database ID Release 759847594Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847594ReactomeR-RNO-4164291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416429.11Reactome Database ID Release 759847596Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847596ReactomeR-RNO-4189451Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418945.1KISS1R:KISS1(68-121)Reactome DB_ID: 9847606Kiss1rKISS1RQ924U1Reactome DB_ID: 9847600UniProt:Q924U1Kiss1rUniProtQ924U11EQUAL398EQUALReactome Database ID Release 759847600Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847600ReactomeR-RNO-3889741Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388974.11Kiss1KISS1(68-121)Q7TSB7Reactome DB_ID: 9847604UniProt:Q7TSB7Kiss1UniProtQ7TSB768EQUAL121EQUALReactome Database ID Release 759847604Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847604ReactomeR-RNO-3890431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389043.11Reactome Database ID Release 759847606Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847606ReactomeR-RNO-3890161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389016.1LPAR1,2,3,5:LPAReactome DB_ID: 98476261Converted from EntitySet in ReactomeLPAR1,2,3,5LPA-binding EDG receptorsReactome DB_ID: 9847624Lpar1LPAR1P61794Reactome DB_ID: 9847610UniProt:P61794Lpar1UniProtP617941EQUAL364EQUALReactome Database ID Release 759847610Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847610ReactomeR-RNO-4193541Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419354.1Lpar2LPAR2A0A0G2K505Reactome DB_ID: 9847614UniProt:A0A0G2K505Lpar2UniProtA0A0G2K5051EQUAL351EQUALReactome Database ID Release 759847614Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847614ReactomeR-RNO-4193931Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419393.1Lpar3LPAR3Q8K5E0Reactome DB_ID: 9847618UniProt:Q8K5E0Lpar3UniProtQ8K5E01EQUAL353EQUALReactome Database ID Release 759847618Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847618ReactomeR-RNO-4193791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419379.1Lpar5LPAR5D4ADR1Reactome DB_ID: 9847622UniProt:D4ADR1Lpar5UniProtD4ADR11EQUAL372EQUALReactome Database ID Release 759847622Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847622ReactomeR-RNO-32494141Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-3249414.1Reactome Database ID Release 759847624Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847624ReactomeR-RNO-4193691Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419369.11Reactome Database ID Release 759847626Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847626ReactomeR-RNO-4193531Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419353.1LTB4R,LTB4R2:LTBReactome DB_ID: 9847638LTB4Leukotriene-B(4) omega-hydroxylaseleukotriene B4Leukotriene-B(4) 20-monooxygenaseReactome DB_ID: 416436leukotriene B4 [ChEBI:15647]leukotriene B4ChEBICHEBI:15647Reactome Database ID Release 75416436Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=416436ReactomeR-ALL-4164363Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-416436.3COMPOUNDC021651Converted from EntitySet in ReactomeLTB4R,LTB4R2LTB4 receptorsReactome DB_ID: 9847636Ltb4rLTB4RQ9R0Q2Reactome DB_ID: 9847630UniProt:Q9R0Q2Ltb4rUniProtQ9R0Q21EQUAL352EQUALReactome Database ID Release 759847630Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847630ReactomeR-RNO-4164101Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416410.1Ltb4r2LTB4R2Q924U0Reactome DB_ID: 9847634UniProt:Q924U0Ltb4r2UniProtQ924U01EQUAL389EQUALReactome Database ID Release 759847634Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847634ReactomeR-RNO-4164131Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416413.1Reactome Database ID Release 759847636Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847636ReactomeR-RNO-4164011Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416401.11Reactome Database ID Release 759847638Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847638ReactomeR-RNO-4164351Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416435.1TACR1:TAC1(58-68)Reactome DB_ID: 9847648Tac1TAC1(58-68)P06767Reactome DB_ID: 9847642UniProt:P06767Tac1UniProtP0676758EQUAL68EQUALReactome Database ID Release 759847642Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847642ReactomeR-RNO-3800661Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380066.11Tacr1TACR1P14600Reactome DB_ID: 9847646UniProt:P14600Tacr1UniProtP146001EQUAL407EQUALReactome Database ID Release 759847646Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847646ReactomeR-RNO-3801031Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380103.11Reactome Database ID Release 759847648Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847648ReactomeR-RNO-3801191Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380119.1TACR2:TAC1(98-107)Reactome DB_ID: 9847656Tacr2TACR2P16610Reactome DB_ID: 9847654UniProt:P16610Tacr2UniProtP166101EQUAL398EQUALReactome Database ID Release 759847654Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847654ReactomeR-RNO-3801351Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380135.11Tac1TAC1(98-107)P06767Reactome DB_ID: 984765098EQUAL107EQUALReactome Database ID Release 759847650Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847650ReactomeR-RNO-3801311Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380131.11Reactome Database ID Release 759847656Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847656ReactomeR-RNO-3833511Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-383351.1TACR3:TAC3Reactome DB_ID: 9847666Tac3TAC3P08435Reactome DB_ID: 9847660UniProt:P08435Tac3UniProtP0843581EQUAL90EQUALReactome Database ID Release 759847660Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847660ReactomeR-RNO-3801331Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380133.11Tacr3TACR3P16177Reactome DB_ID: 9847664UniProt:P16177Tacr3UniProtP161771EQUAL465EQUALReactome Database ID Release 759847664Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847664ReactomeR-RNO-3801321Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380132.11Reactome Database ID Release 759847666Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847666ReactomeR-RNO-3833721Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-383372.1NPFFR1,NPFFR2:NPFF(69-76)Reactome DB_ID: 9847682Converted from EntitySet in ReactomeNPFFR1,NPFFR2Neuropeptide FF receptorReactome DB_ID: 9847680Npffr1NPFFR1Q9EP86Reactome DB_ID: 9847674UniProt:Q9EP86Npffr1UniProtQ9EP861EQUAL430EQUALReactome Database ID Release 759847674Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847674ReactomeR-RNO-3894291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389429.1Npffr2NPFFR2Q9EQD2Reactome DB_ID: 9847678UniProt:Q9EQD2Npffr2UniProtQ9EQD21EQUAL522EQUALReactome Database ID Release 759847678Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847678ReactomeR-RNO-3894761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389476.1Reactome Database ID Release 759847680Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847680ReactomeR-RNO-3894061Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389406.11NpffNPFF(69-76)Q9WVA9Reactome DB_ID: 9847670UniProt:Q9WVA9NpffUniProtQ9WVA969EQUAL76EQUALReactome Database ID Release 759847670Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847670ReactomeR-RNO-3894151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389415.11Reactome Database ID Release 759847682Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847682ReactomeR-RNO-3894591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389459.1NTSR1,NTSR2:NTS(151-163)Reactome DB_ID: 9847698Converted from EntitySet in ReactomeNTSR1,NTSR2Neurotensin receptorsReactome DB_ID: 9847696Ntsr1NTSR1P20789Reactome DB_ID: 9847690UniProt:P20789Ntsr1UniProtP207891EQUAL418EQUALReactome Database ID Release 759847690Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847690ReactomeR-RNO-3889161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388916.1Ntsr2NTSR2Q63384Reactome DB_ID: 9847694UniProt:Q63384Ntsr2UniProtQ633841EQUAL410EQUALReactome Database ID Release 759847694Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847694ReactomeR-RNO-3889181Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388918.1Reactome Database ID Release 759847696Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847696ReactomeR-RNO-3889171Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388917.11NtsNTS(151-163)P20068Reactome DB_ID: 9847686UniProt:P20068NtsUniProtP20068151EQUAL163EQUALReactome Database ID Release 759847686Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847686ReactomeR-RNO-3889151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388915.11Reactome Database ID Release 759847698Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847698ReactomeR-RNO-3889201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388920.1HCRTR1:HCRT(34-66)Reactome DB_ID: 9847708HcrtHCRT(34-66)O55232Reactome DB_ID: 9847702UniProt:O55232HcrtUniProtO5523234EQUAL66EQUALReactome Database ID Release 759847702Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847702ReactomeR-RNO-3895001Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389500.11Hcrtr1HCRTR1P56718Reactome DB_ID: 9847706UniProt:P56718Hcrtr1UniProtP567181EQUAL425EQUALReactome Database ID Release 759847706Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847706ReactomeR-RNO-3894901Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389490.11Reactome Database ID Release 759847708Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847708ReactomeR-RNO-3894411Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389441.1HCRTR2:HCRT(70-97)Reactome DB_ID: 9847716Hcrtr2HCRTR2P56719Reactome DB_ID: 9847714UniProt:P56719Hcrtr2UniProtP567191EQUAL444EQUALReactome Database ID Release 759847714Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847714ReactomeR-RNO-3894211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389421.11HcrtHCRT(70-97)O55232Reactome DB_ID: 984771070EQUAL97EQUALReactome Database ID Release 759847710Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847710ReactomeR-RNO-3894731Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389473.11Reactome Database ID Release 759847716Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847716ReactomeR-RNO-3894491Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389449.1OXTR:OXT(20-28)Reactome DB_ID: 9847726OxtOXT(20-28)P01179Reactome DB_ID: 9847720UniProt:P01179OxtUniProtP0117920EQUAL28EQUALReactome Database ID Release 759847720Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847720ReactomeR-RNO-3884301Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388430.11OxtrOXTRP70536Reactome DB_ID: 9847724UniProt:P70536OxtrUniProtP705361EQUAL389EQUALReactome Database ID Release 759847724Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847724ReactomeR-RNO-3884281Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388428.11Reactome Database ID Release 759847726Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847726ReactomeR-RNO-3884951Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-388495.1Thrombin:Proteinase-activated receptorsReactome DB_ID: 9847734Converted from EntitySet in ReactomeProteinase-activated receptorsReactome DB_ID: 9847732F2rF2R(27-425)P26824Reactome DB_ID: 9830389UniProt:P26824F2rUniProtP2682427EQUAL425EQUALReactome Database ID Release 759830389Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830389ReactomeR-RNO-613091Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-61309.1F2rl2F2RL2(22-374)Q920E1Reactome DB_ID: 9830391UniProt:Q920E1F2rl2UniProtQ920E122EQUAL374EQUALReactome Database ID Release 759830391Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830391ReactomeR-RNO-613131Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-61313.1F2rl3F2RL3(18-385)Q920E0Reactome DB_ID: 9830393UniProt:Q920E0F2rl3UniProtQ920E018EQUAL385EQUALReactome Database ID Release 759830393Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830393ReactomeR-RNO-613151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-61315.1F2rl1F2RL1(37-397)Q63645Reactome DB_ID: 9847730UniProt:Q63645F2rl1UniProtQ6364537EQUAL397EQUALReactome Database ID Release 759847730Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847730ReactomeR-RNO-3894181Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389418.1Reactome Database ID Release 759847732Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847732ReactomeR-RNO-3894581Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389458.11activated thrombin (factor IIa)Reactome DB_ID: 9830411F2thrombin light chainP18292Reactome DB_ID: 9830409UniProt:P18292F2UniProtP18292328EQUAL363EQUALReactome Database ID Release 759830409Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830409ReactomeR-RNO-1405981Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-140598.116F2thrombin heavy chainP18292Reactome DB_ID: 9830407364EQUAL622EQUALReactome Database ID Release 759830407Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830407ReactomeR-RNO-1405891Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-140589.11Reactome Database ID Release 759830411Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830411ReactomeR-RNO-1567861Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-156786.11Reactome Database ID Release 759847734Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847734ReactomeR-RNO-3894701Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389470.1PTGER1:PGE2Reactome DB_ID: 9847740PGE2prostaglandin E2Reactome DB_ID: 391930prostaglandin E2 [ChEBI:15551]prostaglandin E2ChEBICHEBI:15551Reactome Database ID Release 75391930Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=391930ReactomeR-ALL-3919303Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-391930.31Ptger1PTGER1P70597Reactome DB_ID: 9847738UniProt:P70597Ptger1UniProtP705971EQUAL402EQUALReactome Database ID Release 759847738Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847738ReactomeR-RNO-3918381Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391838.11Reactome Database ID Release 759847740Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847740ReactomeR-RNO-3919201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391920.1PTGFR:PGF2aReactome DB_ID: 9847746PtgfrPTGFRP43118Reactome DB_ID: 9847744UniProt:P43118PtgfrUniProtP431181EQUAL359EQUALReactome Database ID Release 759847744Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847744ReactomeR-RNO-3918261Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391826.11PGF2aProstaglandin F2-alphaprostaglandin F2alphaReactome DB_ID: 391928prostaglandin F2alpha [ChEBI:15553]prostaglandin F2alphaChEBICHEBI:15553Reactome Database ID Release 75391928Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=391928ReactomeR-ALL-3919283Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-391928.31Reactome Database ID Release 759847746Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847746ReactomeR-RNO-3919311Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391931.1PAF receptor:PAFReactome DB_ID: 9847752PtafrPTAFRP46002Reactome DB_ID: 9847750UniProt:P46002PtafrUniProtP460021EQUAL342EQUALReactome Database ID Release 759847750Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847750ReactomeR-RNO-4193761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419376.11PAFPlatelet-activating factor2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholineReactome DB_ID: 4193752-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine [ChEBI:52450]2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholineChEBICHEBI:52450Reactome Database ID Release 75419375Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=419375ReactomeR-ALL-4193753Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-419375.31Reactome Database ID Release 759847752Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847752ReactomeR-RNO-4193641Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-419364.1QRFPR:QRFPReactome DB_ID: 9847769Converted from EntitySet in ReactomeHomologues of QRFPRReactome DB_ID: 9847767QRFPRRGD1560028D3Z8C2Reactome DB_ID: 9847761UniProt:D3Z8C2RGD1560028UniProtD3Z8C21EQUAL431EQUALReactome Database ID Release 759847761Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847761ReactomeR-RNO-3895041Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389504.1QrfprQRFPRP83858Reactome DB_ID: 9847765UniProt:P83858QrfprUniProtP838581EQUAL431EQUALReactome Database ID Release 759847765Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847765ReactomeR-RNO-389504-21Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389504-2.1Reactome Database ID Release 759847767Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847767ReactomeR-RNO-389504-31Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389504-3.11QrfpQRFPP83860Reactome DB_ID: 9847757UniProt:P83860QrfpUniProtP8386091EQUAL133EQUALReactome Database ID Release 759847757Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847757ReactomeR-RNO-3893991Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389399.11Reactome Database ID Release 759847769Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847769ReactomeR-RNO-3894071Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-389407.1XCR1:XCL1,XCL2Reactome DB_ID: 9846034Xcl1XCL2P51672Reactome DB_ID: 9846028UniProt:P51672Xcl1UniProtP5167222EQUAL114EQUALReactome Database ID Release 759846028Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846028ReactomeR-RNO-3733491Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-373349.11Xcr1XCR1D3ZGG9Reactome DB_ID: 9846032UniProt:D3ZGG9Xcr1UniProtD3ZGG91EQUAL333EQUALReactome Database ID Release 759846032Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846032ReactomeR-RNO-3731091Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-373109.11Reactome Database ID Release 759846034Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9846034ReactomeR-RNO-3733571Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-373357.1TRH:TRHRReactome DB_ID: 9847789TrhrTRHRQ01717Reactome DB_ID: 9847773UniProt:Q01717TrhrUniProtQ017171EQUAL398EQUALReactome Database ID Release 759847773Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847773ReactomeR-RNO-4445561Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444556.11TrhTRH(227-229)P01150Reactome DB_ID: 9847777UniProt:P01150TrhUniProtP01150227EQUAL229EQUALReactome Database ID Release 759847777Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847777ReactomeR-RNO-4445481Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444548.11Reactome Database ID Release 759847789Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847789ReactomeR-RNO-4444791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444479.1NPSR1:NPSReactome DB_ID: 9847799NpsNPSP0C0P7Reactome DB_ID: 9847793UniProt:P0C0P7NpsUniProtP0C0P770EQUAL89EQUALReactome Database ID Release 759847793Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847793ReactomeR-RNO-4447111Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444711.11Npsr1NPSR1P0C0L6Reactome DB_ID: 9847797UniProt:P0C0L6Npsr1UniProtP0C0L61EQUAL371EQUALReactome Database ID Release 759847797Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847797ReactomeR-RNO-4447041Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444704.11Reactome Database ID Release 759847799Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847799ReactomeR-RNO-4447261Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444726.1PROKR1,PROKR2:PROK1,PROK2Reactome DB_ID: 9847821Converted from EntitySet in ReactomePROK1,PROK2ProkineticinReactome DB_ID: 9847819Prok1PROK1Q8R414Reactome DB_ID: 9847813UniProt:Q8R414Prok1UniProtQ8R41420EQUAL105EQUALReactome Database ID Release 759847813Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847813ReactomeR-RNO-4446161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444616.1Prok2PROK2Q8R413Reactome DB_ID: 9847817UniProt:Q8R413Prok2UniProtQ8R41328EQUAL129EQUALReactome Database ID Release 759847817Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847817ReactomeR-RNO-4446601Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444660.1Reactome Database ID Release 759847819Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847819ReactomeR-RNO-4446921Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444692.11Converted from EntitySet in ReactomePROKR1,PROKR2Prokineticin receptorsReactome DB_ID: 9847809Prokr1PROKR1Q8R416Reactome DB_ID: 9847803UniProt:Q8R416Prokr1UniProtQ8R4161EQUAL393EQUALReactome Database ID Release 759847803Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847803ReactomeR-RNO-4446681Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444668.1Prokr2PROKR2Q8R415Reactome DB_ID: 9847807UniProt:Q8R415Prokr2UniProtQ8R4151EQUAL384EQUALReactome Database ID Release 759847807Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847807ReactomeR-RNO-4446371Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444637.1Reactome Database ID Release 759847809Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847809ReactomeR-RNO-4446281Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444628.11Reactome Database ID Release 759847821Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847821ReactomeR-RNO-4447301Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444730.1UTSR:UTS2,UTS2BReactome DB_ID: 9847837Converted from EntitySet in ReactomeUTS2,UTS2BUrotensin 2, 2BReactome DB_ID: 9847835Uts2UTS2Q9QZQ4Reactome DB_ID: 9847829UniProt:Q9QZQ4Uts2UniProtQ9QZQ4114EQUAL124EQUALReactome Database ID Release 759847829Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847829ReactomeR-RNO-4451221Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-445122.1Uts2bUTS2BQ765I2Reactome DB_ID: 9847833UniProt:Q765I2Uts2bUniProtQ765I2112EQUAL119EQUALReactome Database ID Release 759847833Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847833ReactomeR-RNO-4451001Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-445100.1Reactome Database ID Release 759847835Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847835ReactomeR-RNO-4451151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-445115.11Uts2rUTS2RP49684Reactome DB_ID: 9847825UniProt:P49684Uts2rUniProtP496841EQUAL389EQUALReactome Database ID Release 759847825Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847825ReactomeR-RNO-4451141Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-445114.11Reactome Database ID Release 759847837Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847837ReactomeR-RNO-4451191Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-445119.1FFAR1:FFAR1 ligandsReactome DB_ID: 9847843Converted from EntitySet in ReactomeFFAR1 ligandsReactome DB_ID: 400427PALMpalmitic acidhexadecanoic acidPalmitateReactome DB_ID: 400452hexadecanoic acid [ChEBI:15756]hexadecanoic acidChEBICHEBI:15756Reactome Database ID Release 75400452Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400452ReactomeR-ALL-4004523Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400452.3COMPOUNDC00249Pentadecanoic acidReactome DB_ID: 400428pentadecanoic acid [ChEBI:42504]pentadecanoic acidChEBICHEBI:42504Reactome Database ID Release 75400428Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400428ReactomeR-ALL-4004282Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400428.2OLEA(9Z)-octadec-9-enoic acidoleic acidReactome DB_ID: 400431oleic acid [ChEBI:16196]oleic acidChEBICHEBI:16196Reactome Database ID Release 75400431Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400431ReactomeR-ALL-4004313Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400431.3DDCXlauric aciddodecanoic acidDodecylcarboxylateDodecanoateReactome DB_ID: 449678dodecanoic acid [ChEBI:30805]dodecanoic acidChEBICHEBI:30805Reactome Database ID Release 75449678Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=449678ReactomeR-ALL-4496783Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-449678.3COMPOUNDC02679RGZrosiglitazoneReactome DB_ID: 449680rosiglitazone [ChEBI:50122]rosiglitazoneChEBICHEBI:50122Reactome Database ID Release 75449680Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=449680ReactomeR-ALL-4496803Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-449680.3Reactome Database ID Release 75400427Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400427ReactomeR-ALL-4004272Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400427.21Ffar1FFAR1Q8K3T4Reactome DB_ID: 9847841UniProt:Q8K3T4Ffar1UniProtQ8K3T41EQUAL300EQUALReactome Database ID Release 759847841Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847841ReactomeR-RNO-4004411Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400441.11Reactome Database ID Release 759847843Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847843ReactomeR-RNO-4004201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400420.1FFAR2:FFAR2 ligandsReactome DB_ID: 9847849Converted from EntitySet in ReactomeFFAR2 ligandsReactome DB_ID: 444210CH3COO-Acetateacetic acidEthanoic acidReactome DB_ID: 372540acetic acid [ChEBI:15366]acetic acidChEBICHEBI:15366Reactome Database ID Release 75372540Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=372540ReactomeR-ALL-3725403Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-372540.3COMPOUNDC00033PropionateEtCOO- or C2H5COO-propionic acidPropanoic acidReactome DB_ID: 429737propionic acid [ChEBI:30768]propionic acidChEBICHEBI:30768Reactome Database ID Release 75429737Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=429737ReactomeR-ALL-4297373Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-429737.3BUTButyratebutyric acidReactome DB_ID: 429760butyric acid [ChEBI:30772]butyric acidChEBICHEBI:30772Reactome Database ID Release 75429760Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=429760ReactomeR-ALL-4297603Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-429760.3COMPOUNDC00246ValeratePentanoateReactome DB_ID: 444051valerate [ChEBI:31011]valeratepentanoateChEBICHEBI:31011Reactome Database ID Release 75444051Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444051ReactomeR-ALL-4440512Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444051.2HXAcaproatehexanoateReactome DB_ID: 444194hexanoate [ChEBI:17120]hexanoateChEBICHEBI:17120Reactome Database ID Release 75444194Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444194ReactomeR-ALL-4441943Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444194.3HCOOHFormateformic acidMethanoic acidReactome DB_ID: 444084formic acid [ChEBI:30751]formic acidChEBICHEBI:30751Reactome Database ID Release 75444084Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444084ReactomeR-ALL-4440843Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444084.3COMPOUNDC00058Reactome Database ID Release 75444210Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444210ReactomeR-ALL-4442102Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444210.21Ffar2FFAR2Q76EI6Reactome DB_ID: 9847847UniProt:Q76EI6Ffar2UniProtQ76EI61EQUAL330EQUALReactome Database ID Release 759847847Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847847ReactomeR-RNO-4439441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-443944.11Reactome Database ID Release 759847849Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847849ReactomeR-RNO-4441741Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444174.1FFAR3:FFAR3 ligandsReactome DB_ID: 9847855Ffar3FFAR3B2GV46Reactome DB_ID: 9847853UniProt:B2GV46Ffar3UniProtB2GV461EQUAL346EQUALReactome Database ID Release 759847853Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847853ReactomeR-RNO-4439511Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-443951.11Converted from EntitySet in ReactomeFFAR3 ligandsReactome DB_ID: 444074Reactome Database ID Release 75444074Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444074ReactomeR-ALL-4440742Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444074.21Reactome Database ID Release 759847855Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847855ReactomeR-RNO-4440481Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444048.1pH sensing receptors:H+Reactome DB_ID: 9847876H+hydronReactome DB_ID: 351626hydron [ChEBI:15378]hydronChEBICHEBI:15378Reactome Database ID Release 75351626Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351626ReactomeR-ALL-3516264Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-351626.4COMPOUNDC000801Converted from EntitySet in ReactomepH sensing receptorsReactome DB_ID: 9847874Gpr4GPR4Q4KLH9Reactome DB_ID: 9847859UniProt:Q4KLH9Gpr4UniProtQ4KLH91EQUAL362EQUALReactome Database ID Release 759847859Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847859ReactomeR-RNO-4447081Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444708.1Gpr65GPR65B0YIR8Reactome DB_ID: 9847863UniProt:B0YIR8Gpr65UniProtB0YIR81EQUAL337EQUALReactome Database ID Release 759847863Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847863ReactomeR-RNO-4446241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444624.1Gpr68GPR68D3ZSW1Reactome DB_ID: 9847868UniProt:D3ZSW1Gpr68UniProtD3ZSW11EQUAL365EQUALReactome Database ID Release 759847868Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847868ReactomeR-RNO-4446251Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444625.1Gpr132GPR132D3ZIH1Reactome DB_ID: 9847872UniProt:D3ZIH1Gpr132UniProtD3ZIH11EQUAL380EQUALReactome Database ID Release 759847872Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847872ReactomeR-RNO-4446991Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444699.1Reactome Database ID Release 759847874Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847874ReactomeR-RNO-4447361Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444736.11Reactome Database ID Release 759847876Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847876ReactomeR-RNO-4447391Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444739.1Gastrin:CCKBRReactome DB_ID: 98478821GastGAST(76-92)P04563Reactome DB_ID: 9847880UniProt:P04563GastUniProtP0456376EQUAL92EQUALReactome Database ID Release 759847880Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847880ReactomeR-RNO-8702661Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-870266.11Reactome Database ID Release 759847882Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847882ReactomeR-RNO-8702621Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-870262.1Acyl ghrelin:GHSRReactome DB_ID: 9847897GhsrGHSRO08725Reactome DB_ID: 9847885UniProt:O08725 GhsrGhsrFUNCTION Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine) (By similarity).SIMILARITY Belongs to the G-protein coupled receptor 1 family.UniProtO087251EQUAL366EQUALReactome Database ID Release 759847885Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847885ReactomeR-RNO-9476591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947659.11Converted from EntitySet in ReactomeAcyl GhrelinReactome DB_ID: 9847895GhrlDecS-GHRL-1(24-50)Q9QYH7Reactome DB_ID: 9847889UniProt:Q9QYH7 GhrlGhrlFUNCTION Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.FUNCTION Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.TISSUE SPECIFICITY Ghrelin is broadly expressed with higher expression in the stomach. Very low levels are detected in the hypothalamus, heart, lung, pancreas, intestine and adipose tissue. Obestatin is most highly expressed in jejunum, and also found in duodenum, stomach, pituitary, ileum, liver, hypothalamus and heart. Expressed in low levels in pancreas, cerebellum, cerebrum, kidney, testis, ovary colon and lung.PTM O-octanoylation is essential for ghrelin activity. The replacement of Ser-26 by aromatic tryptophan preserves ghrelin activity (PubMed:10604470, PubMed:10801861).PTM Amidation of Leu-98 is essential for obestatin activity.SIMILARITY Belongs to the motilin family.CAUTION PubMed:16284174 reports obestatin as ligand of GPR39. However, PubMed:17289961 and others are unable to reproduce these results. It also seems to be unclear whether obestatin has opposite effects on food intake compared with ghrelin.UniProtQ9QYH726EQUALO-decanoyl-L-serineMODMOD:0039024EQUAL50EQUALReactome Database ID Release 759847889Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847889ReactomeR-RNO-4220691Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-422069.1GhrlOctanoyl-ghrelinAppetite-regulating hormoneGHRL_RATReactome DB_ID: 94764326EQUALO-octanoyl-L-serineMODMOD:0029524EQUAL51EQUALReactome Database ID Release 75947643Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=947643ReactomeR-RNO-9476431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947643.1Reactome Database ID Release 759847895Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847895ReactomeR-RNO-4220961Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-422096.11Reactome Database ID Release 759847897Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847897ReactomeR-RNO-9476441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947644.1MCHR1,MCHR2:PMCH(147-165)Reactome DB_ID: 9847907Mchr1MCHR1P97639Reactome DB_ID: 9847901UniProt:P97639Mchr1UniProtP976391EQUAL422EQUALReactome Database ID Release 759847901Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847901ReactomeR-RNO-9476821Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947682.11PmchPMCH(147-165)P14200Reactome DB_ID: 9847905UniProt:P14200PmchUniProtP14200147EQUAL165EQUALReactome Database ID Release 759847905Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847905ReactomeR-RNO-9476851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947685.11Reactome Database ID Release 759847907Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847907ReactomeR-RNO-9476701Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-947670.1NMUR2:NMSReactome DB_ID: 9847917NmsNMSQ5H8A2Reactome DB_ID: 9847915UniProt:Q5H8A2NmsUniProtQ5H8A2109EQUAL141EQUALReactome Database ID Release 759847915Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847915ReactomeR-RNO-9647961Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964796.11Nmur2NMUR2Q9ESQ4Reactome DB_ID: 9847911UniProt:Q9ESQ4Nmur2UniProtQ9ESQ41EQUAL415EQUALReactome Database ID Release 759847911Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847911ReactomeR-RNO-9648161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964816.11Reactome Database ID Release 759847917Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847917ReactomeR-RNO-9818311Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-981831.1NMUR1,NMUR2:NMUReactome DB_ID: 9847929Converted from EntitySet in ReactomeNMUR1,NMUR2Neuromedin-U receptorsReactome DB_ID: 9847923Nmur1NMUR1Q9JJI5Reactome DB_ID: 9847921UniProt:Q9JJI5Nmur1UniProtQ9JJI51EQUAL426EQUALReactome Database ID Release 759847921Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847921ReactomeR-RNO-9647901Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964790.1Reactome Database ID Release 759847923Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847923ReactomeR-RNO-9648051Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964805.11NmuNMUP12760Reactome DB_ID: 9847927UniProt:P12760NmuUniProtP12760142EQUAL166EQUALReactome Database ID Release 759847927Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847927ReactomeR-RNO-9648171Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964817.11Reactome Database ID Release 759847929Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847929ReactomeR-RNO-9648021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-964802.1Group I Metabotropic glutamate receptors:GluReactome DB_ID: 9847931Converted from EntitySet in ReactomeGRM1,GRM5Group I Metabotropic glutamate receptorsReactome DB_ID: 9845962Grm1GRM1P23385Reactome DB_ID: 9845956UniProt:P23385Grm1UniProtP2338519EQUAL1194EQUALReactome Database ID Release 759845956Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9845956ReactomeR-RNO-4205211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420521.1Grm5GRM5P31424Reactome DB_ID: 9845960UniProt:P31424Grm5UniProtP3142421EQUAL1212EQUALReactome Database ID Release 759845960Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9845960ReactomeR-RNO-4205531Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420553.1Reactome Database ID Release 759845962Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9845962ReactomeR-RNO-4205661Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-420566.11L-GluL-GlutamateL-glutamate(1-)L-glutamic acidL-Glutaminic acidReactome DB_ID: 210382L-glutamate(1-) [ChEBI:29985]L-glutamate(1-)L-glutamic acid, ion(1-)[NH3+][C@@H](CCC([O-])=O)C([O-])=OWHUUTDBJXJRKMK-VKHMYHEASA-MC5H8NO4146.12136(2S)-2-ammoniopentanedioatehydrogen L-glutamateL-glutamateL-glutamic acid monoanionInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1ChEBICHEBI:29985Reactome Database ID Release 75210382Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=210382ReactomeR-ALL-2103824Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-210382.4COMPOUNDC000251Reactome Database ID Release 759847931Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847931ReactomeR-RNO-32225831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-3222583.1GPR143:L-DopaReactome DB_ID: 9847937DopaL-Dopa3,4-Dihydroxy-L-phenylalanineReactome DB_ID: 8851314L-dopa [ChEBI:15765]L-dopaChEBICHEBI:15765Reactome Database ID Release 758851314Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=8851314ReactomeR-ALL-88513142Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-8851314.2COMPOUNDC003551Gpr143GPR143D4A082Reactome DB_ID: 9847935UniProt:D4A082Gpr143UniProtD4A0821EQUAL404EQUALReactome Database ID Release 759847935Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847935ReactomeR-RNO-88512921Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-8851292.11Reactome Database ID Release 759847937Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847937ReactomeR-RNO-88513021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-8851302.1FFAR4:FFAR4 ligandsReactome DB_ID: 9847943Ffar4FFAR4Q2AC31Reactome DB_ID: 9847941UniProt:Q2AC31Ffar4UniProtQ2AC311EQUAL377EQUALReactome Database ID Release 759847941Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847941ReactomeR-RNO-4005021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400502.11Converted from EntitySet in ReactomeFFAR4 ligandsGPR120 ligandsReactome DB_ID: 40055111,14,17-eicosatrienoic acidall-cis-icosa-11,14,17-trienoic acidReactome DB_ID: 444192all-cis-icosa-11,14,17-trienoic acid [ChEBI:53460]all-cis-icosa-11,14,17-trienoic acidChEBICHEBI:53460Reactome Database ID Release 75444192Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444192ReactomeR-ALL-4441923Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444192.38,11,14-Eicosatrienoic acidall-cis-icosa-8,11,14-trienoic acidReactome DB_ID: 444200all-cis-icosa-8,11,14-trienoic acid [ChEBI:53486]all-cis-icosa-8,11,14-trienoic acidChEBICHEBI:53486Reactome Database ID Release 75444200Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444200ReactomeR-ALL-4442003Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444200.3ELDAelaidic acidReactome DB_ID: 400481elaidic acid [ChEBI:27997]elaidic acidacide elaidiqueElaidinsaure9-Octadecenoic acid, (E)-(E)-9-Octadecenoic acid(E)-Oleic acidD9-trans-Octadecenoic acid9-trans-Octadecenoic acidtrans-D9-Octadecenoic acidtrans-9-Octadecenoic acidtrans-Elaidic acidtrans-Oleic acidChEBICHEBI:27997Reactome Database ID Release 75400481Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400481ReactomeR-ALL-4004813Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400481.3EPAeicosapentaenoic acidall-cis-5,8,11,14,17-icosapentaenoic acidReactome DB_ID: 9020469all-cis-5,8,11,14,17-icosapentaenoic acid [ChEBI:28364]all-cis-5,8,11,14,17-icosapentaenoic acidChEBICHEBI:28364Reactome Database ID Release 759020469Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9020469ReactomeR-ALL-90204693Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-9020469.3MYSAmyristic acidtetradecanoic acidReactome DB_ID: 400514tetradecanoic acid [ChEBI:28875]tetradecanoic acidChEBICHEBI:28875Reactome Database ID Release 75400514Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400514ReactomeR-ALL-4005143Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400514.3STEAStearatemagnesium distearateReactome DB_ID: 400530magnesium distearate [ChEBI:9254]magnesium distearateChEBICHEBI:9254Reactome Database ID Release 75400530Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400530ReactomeR-ALL-4005303Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400530.3ALAalpha-linolenic acidReactome DB_ID: 400506alpha-linolenic acid [ChEBI:27432]alpha-linolenic acidChEBICHEBI:27432Reactome Database ID Release 75400506Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400506ReactomeR-ALL-4005063Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400506.3GLAgamma-linolenic acidReactome DB_ID: 400528gamma-linolenic acid [ChEBI:28661]gamma-linolenic acidChEBICHEBI:28661Reactome Database ID Release 75400528Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400528ReactomeR-ALL-4005283Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400528.3Pmoapalmitoleic acid(9Z)-hexadecenoic acidReactome DB_ID: 400486palmitoleic acid [ChEBI:28716]palmitoleic acidChEBICHEBI:28716Reactome Database ID Release 75400486Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400486ReactomeR-ALL-4004863Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400486.3DTTADocosatetraenoic acidall-cis-docosa-7,10,13,16-tetraenoic acidReactome DB_ID: 444170all-cis-docosa-7,10,13,16-tetraenoic acid [ChEBI:53487]all-cis-docosa-7,10,13,16-tetraenoic acidChEBICHEBI:53487Reactome Database ID Release 75444170Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444170ReactomeR-ALL-4441703Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444170.3DPADocosapentaenoic acid(7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acidall-cis-7,10,13,16,19-Docosapentaenoic acidReactome DB_ID: 444178(7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid [ChEBI:53488](7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acidChEBICHEBI:53488Reactome Database ID Release 75444178Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=444178ReactomeR-ALL-4441783Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-444178.3DHADocosahexaenoic acidall-cis-docosa-4,7,10,13,16,19-hexaenoic acidcis-4,7,10,13,16,19-docosahexaenoic acidReactome DB_ID: 400493all-cis-docosa-4,7,10,13,16,19-hexaenoic acid [ChEBI:28125]all-cis-docosa-4,7,10,13,16,19-hexaenoic acidChEBICHEBI:28125Reactome Database ID Release 75400493Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400493ReactomeR-ALL-4004933Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400493.3Reactome Database ID Release 75400551Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=400551ReactomeR-ALL-4005513Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-400551.31Reactome Database ID Release 759847943Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847943ReactomeR-RNO-4005431Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400543.1GPR39:Zn2+Reactome DB_ID: 9847949Zn2+Zn++zinc(2+)Zinc ionZn(II)Reactome DB_ID: 158417zinc(2+) [ChEBI:29105]zinc(2+)ChEBICHEBI:29105Reactome Database ID Release 75158417Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=158417ReactomeR-ALL-1584173Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-158417.3COMPOUNDC000381GPR39A0A0G2K966Reactome DB_ID: 9847947UniProt:A0A0G2K966UniProtA0A0G2K9661EQUAL453EQUALReactome Database ID Release 759847947Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847947ReactomeR-RNO-4439531Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-443953.11Reactome Database ID Release 759847949Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847949ReactomeR-RNO-4445751Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-444575.1Reactome Database ID Release 759847951Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847951ReactomeR-RNO-3801101Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-380110.11Reactome Database ID Release 759847953Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847953ReactomeR-RNO-7494511Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-749451.1Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active)Reactome DB_ID: 9847955Heterotrimeric G-protein Gq (active)Reactome DB_ID: 9830160G-protein alpha (q/11): GTPReactome DB_ID: 983015811Reactome Database ID Release 759830158Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830158ReactomeR-RNO-1145341Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-114534.111Reactome Database ID Release 759830160Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830160ReactomeR-RNO-1145541Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-114554.111Reactome Database ID Release 759847955Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847955ReactomeR-RNO-7494471Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-749447.1GDPGuanosine 5'-diphosphateGuanosine diphosphateReactome DB_ID: 29420Reactome Database ID Release 7529420Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29420ReactomeR-ALL-294202Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-29420.2COMPOUNDC00035ACTIVATIONLTC4:CyslTR1,2Reactome DB_ID: 98479591Converted from EntitySet in ReactomeCYSLTR1,CYSLTR2Cysteinyl leukotriene receptorsReactome DB_ID: 9847957Reactome Database ID Release 759847957Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847957ReactomeR-RNO-4163851Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416385.11Reactome Database ID Release 759847959Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847959ReactomeR-RNO-96643021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-9664302.1GENE ONTOLOGYGO:0005085gene ontology term for cellular functionMIMI:0355Same Catalyst ActivityReactome Database ID Release 759847960Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847960Reactome Database ID Release 759847962Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9847962ReactomeR-RNO-3790481Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-379048.1G alpha q protein (or Gq/11) consists of four family members (G-alpha 11, -alpha 14, -alpha 15 and -alpha q). It activates phospholipase C (PLC) (Dowal L et al, 2006). PLC hydrolyzes phosphatidylinositol (PIP2) to diacyl glycerol (DAG) and inositol triphosphate (IP3). DAG acts as a second messenger that activates protein kinase C (PKC) and IP3 can bind to IP3 receptors, particular calcium channels in the endoplasmic reticulum (ER). Calcium flow causes the cytosolic concentration of calcium to increase, causing a cascade of intracellular changes and activity. 8664309Pubmed1996Human G(alpha q): cDNA and tissue distributionChen, BLeverette, RDSchwinn, DAKwatra, MMBiochim Biophys Acta 1281:125-83086311Pubmed1986The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteinsFerguson, KMHigashijima, TSmigel, MDGilman, AGJ Biol Chem 261:7393-916754659Pubmed2006Stable association between G alpha(q) and phospholipase C beta 1 in living cellsDowal, LProvitera, PScarlata, SJ Biol Chem 281:23999-40141905813Pubmed1991G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cellsAmatruda TT, 3rdSteele, DASlepak, VZSimon, MIProc Natl Acad Sci U S A 88:5587-9110191087Pubmed1999Genomic organization of the human galpha14 and Galphaq genes and mutation analysis in chorea-acanthocytosis (CHAC)Rubio, JPLevy, ERDobson-Stone, CMonaco, APGenomics 57:84-93inferred from electronic annotationEVIDENCE CODEECO:0000203LEFT-TO-RIGHTGRK2 sequesters activated GqThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Grk2GRK2P26817Reactome DB_ID: 9829407UniProt:P26817Grk2UniProtP268171EQUAL689EQUALReactome Database ID Release 759829407Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829407ReactomeR-RNO-502701Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-50270.1G-protein alpha (q):GRK2Reactome DB_ID: 985324411Reactome Database ID Release 759853244Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853244ReactomeR-RNO-4165151Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416515.1Reactome Database ID Release 759853246Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853246ReactomeR-RNO-4165161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416516.1GRK2 can inhibit GPCR signaling via phosphorylation-independent sequestration of Gq/11/14 subunits utilising its RGS homology (RH) domain. GRK2 may be an effector of activated Gq, initiating signalling cascades other than the classical PLC beta signalling associated with Gq.10727532Pubmed2000Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaqSallese, MMariggiò, SD'Urbano, EIacovelli, LDe Blasi, AMol. Pharmacol. 57:826-3116339447Pubmed2005Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complexTesmer, VMKawano, TShankaranarayanan, AKozasa, TTesmer, JJScience 310:1686-9018936096Pubmed2008Assembly of high order G alpha q-effector complexes with RGS proteinsShankaranarayanan, AThal, DMTesmer, VMRoman, DLNeubig, RRKozasa, TTesmer, JJJ Biol Chem 283:34923-3410567430Pubmed1999Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2Carman, CVParent, JLDay, PWPronin, ANSternweis, PMWedegaertner, PBGilman, AGBenovic, JLKozasa, TJ Biol Chem 274:34483-92LEFT-TO-RIGHTG alpha (q) binds to Trio family RhoGEFsThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Converted from EntitySet in ReactomeTRIO family RhoGEFsTrio family RhoGEFsReactome DB_ID: 9853127TrioTRIOF1M0Z1Reactome DB_ID: 9839020UniProt:F1M0Z1TrioUniProtF1M0Z11EQUAL3097EQUALReactome Database ID Release 759839020Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9839020ReactomeR-RNO-29806051Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-2980605.1Q6P720Arhgef25ARHGEF25Reactome DB_ID: 9853125UniProt:Q6P720Arhgef25UniProtQ6P7201EQUAL580EQUALReactome Database ID Release 759853125Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853125ReactomeR-RNO-3999591Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-399959.1KalrnKALRNP97924Reactome DB_ID: 9839112UniProt:P97924KalrnUniProtP979241EQUAL2985EQUALReactome Database ID Release 759839112Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9839112ReactomeR-RNO-30065051Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-3006505.1Reactome Database ID Release 759853127Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853127ReactomeR-RNO-3999631Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-399963.1G-protein alpha (q/11):Trio family RhoGEFsReactome DB_ID: 985312911Reactome Database ID Release 759853129Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853129ReactomeR-RNO-4006081Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400608.1Reactome Database ID Release 759853131Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853131ReactomeR-RNO-4005861Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-400586.1The Trio family of RhoA guanine nucleotide exchange factors (RhoGEFs) are directly activated by G alpha (q), possibly within a Gq:Trio:RhoA signalling complex, thereby linking Gq to RhoA-mediated processes such as cell migration, proliferation, and contraction. Like most other RhoGEFs, they have a tandem motif consisting of a Dbl homology (DH) and a pleckstrin homology (PH) domain. Trio and Duet have a number of other domains including an immunoglobin domains that may be involved in interacting with Rho, but the considerably smaller GEFT (p63RhoGEF) does not have any identifiable additional domains yet appears to be sufficient to mediate the activation of RhoA by G alpha (q). The structure represented by GEFT is proposed to represent the core of an ancient signal transduction pathway.17942708Pubmed2007Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegansWilliams, SLLutz, SCharlie, NKVettel, CAilion, MCoco, CTesmer, JJJorgensen, EMWieland, TMiller, KGGenes Dev 21:2731-46LEFT-TO-RIGHTG alpha (q) inhibits PI3K alphaThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>PI3K alphaReactome DB_ID: 9830058Pik3caPIK3CAA0A0G2K344Reactome DB_ID: 9826583UniProt:A0A0G2K344 Pik3caPik3caFUNCTION Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology (By similarity). Participates in cellular signaling in response to various growth factors (By similarity). Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinase ligands such as EGF, IGF1, VEGFA and PDGF (By similarity). Also involved in the activation of AKT1 upon stimulation by receptor tyrosine kinase ligand insulin (PubMed:20236230). Involved in signaling via insulin-receptor substrate (IRS) proteins (By similarity). Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity (By similarity). Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF (By similarity). Regulates invadopodia formation through the PDPK1-AKT1 pathway (By similarity). Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway (By similarity). Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway (By similarity). Also has serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS (By similarity). Plays a role in the positive regulation of phagocytosis and pinocytosis (By similarity).SUBUNIT Heterodimer of a catalytic subunit PIK3CA and a p85 regulatory subunit (PIK3R1, PIK3R2 or PIK3R3). Interacts with IRS1 in nuclear extracts. Interacts with RUFY3. Interacts with RASD2. Interacts with APPL1. Interacts with HRAS and KRAS. Interaction with HRAS/KRAS is required for PI3K pathway signaling and cell proliferation stimulated by EGF and FGF2. Interacts with FAM83B; activates the PI3K/AKT signaling cascade.TISSUE SPECIFICITY Detected in the hypothalamus (at protein level).DOMAIN The PI3K-ABD domain and the PI3K-RBD domain interact with the PI3K/PI4K kinase domain. The C2 PI3K-type domain may facilitate the recruitment to the plasma membrane. The inhibitory interactions with PIK3R1 are mediated by the PI3K-ABD domain and the C2 PI3K-type domain with the iSH2 (inter-SH2) region of PIK3R1, and the C2 PI3K-type domain, the PI3K helical domain, and the PI3K/PI4K kinase domain with the nSH2 (N-terminal SH2) region of PIK3R1.SIMILARITY Belongs to the PI3/PI4-kinase family.UniProtA0A0G2K3441EQUAL1068EQUALReactome Database ID Release 759826583Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9826583ReactomeR-RNO-747871Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-74787.11Converted from EntitySet in ReactomePI3K-regulatory subunitsReactome DB_ID: 9830056Pik3r1PIK3R1Q63787Reactome DB_ID: 9826575UniProt:Q63787 Pik3r1Pik3r1FUNCTION Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).SUBUNIT Heterodimer of a regulatory subunit PIK3R1 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts (via SH2 domains) with CCDC88A/GIV (tyrosine-phosphorylated form); the interaction enables recruitment of PIK3R1 to the EGFR receptor, enhancing PI3K activity and cell migration (By similarity). Interacts with phosphorylated LAT, LAX1, TRAT1 and LIME1 upon TCR and/or activation. Interacts with phosphorylated TOM1L1. Interacts with CBLB. The SH2 domains interact with the YTHM motif of phosphorylated INSR in vitro. Also interacts with tyrosine-phosphorylated IGF1R in vitro. Interacts with CD28 and CD3Z upon T-cell activation. Interacts with NISCH, SOCS7 and HCST. Interacts with RUFY3. Interacts with AXL, FASLG, FER, FGR, HCK, KIT and BCR. Interacts with PDGFRA (tyrosine phosphorylated) and PDGFRB (tyrosine phosphorylated). Interacts (via SH2 domain) with CSF1R (tyrosine phosphorylated). Interacts with ERBB4 (phosphorylated). Interacts (via SH2 domain) with TEK/TIE2 (tyrosine phosphorylated). Interacts with LYN (via SH3 domain); this enhances enzyme activity. Interacts with NTRK1 (phosphorylated upon ligand-binding). Interacts with PIK3R2; the interaction is dissociated in an insulin-dependent manner. Interacts with XBP1; the interaction is direct and induces translocation of XBP1 into the nucleus in a ER stress- and/or insulin-dependent but PI3K-independent manner (By similarity). Interacts with FGFR1, FGFR2, FGFR3 and FGFR4 (phosphorylated) (Probable). Interacts with IRS1 and phosphorylated IRS4 (PubMed:8628286). Interacts with PTK2/FAK1 (PubMed:8824286). Interacts with FAM83B; activates the PI3K/AKT signaling cascade (By similarity). Interacts with APPL1 and APPL2 (By similarity). Interacts with SRC (By similarity). Interacts with ALOX5; this interaction bridges ALOX5 with CD40 after CD40 ligation in B cells and leads to the production of reactive oxygen species (ROS) (By similarity).TISSUE SPECIFICITY The P85-alpha isoform is widely expressed. Expression of the P55-alpha isoform is highest in brain and skeletal muscle. The P50-alpha isoform is abundant in liver with lower levels in brain and muscle.DOMAIN The SH3 domain mediates the binding to CBLB.PTM Polyubiquitinated in T-cells by CBLB; which does not promote proteasomal degradation but impairs association with CD28 and CD3Z upon T-cell activation.PTM Phosphorylated. Tyrosine phosphorylated in response to signaling by FGFR1, FGFR2, FGFR3 and FGFR4. Phosphorylated by CSF1R. Phosphorylated on tyrosine residues by TEK/TIE2. Dephosphorylated by PTPRJ. Phosphorylated by PIK3CA at Ser-608; phosphorylation is stimulated by insulin and PDGF. The relevance of phosphorylation by PIK3CA is however unclear. Phosphorylated in response to KIT and KITLG/SCF. Phosphorylated by FGR and ERBB4 (By similarity).SIMILARITY Belongs to the PI3K p85 subunit family.UniProtQ637871EQUAL724EQUALReactome Database ID Release 759826575Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9826575ReactomeR-RNO-747891Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-74789.1Pik3r2PIK3R2Q63788Reactome DB_ID: 9826578UniProt:Q63788 Pik3r2Pik3r2FUNCTION Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy. Promotes nuclear translocation of XBP1 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).SUBUNIT Heterodimer of a regulatory subunit PIK3R2 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Interacts with FLT1 (tyrosine-phosphorylated) and FLT4 (tyrosine-phosphorylated). Interacts with NYAP1, NYAP2 and MYO16. Interacts with FBXL2; PIK3R2 is a substrate of the SCF(FBXL2) complex. Interacts with PTPN13; dephosphorylates PIK3R2. Interacts with XBP1; the interaction is direct and induces translocation of XBP1 into the nucleus in a ER stress- and/or insulin-dependent but PI3K-independent manner. Interacts with PIK3R1; the interaction is dissociated in an insulin-dependent manner (By similarity). Interacts with SRC (By similarity).DOMAIN The SH2 2 domain is required for interaction with FBXL2 and PTPN13.PTM Phosphorylated in response to signaling from activated receptor-type protein kinases. Dephosphorylated by PTPRJ. Dephosphorylated at Tyr-649 by PTPN13. Phosphorylation of Tyr-649 impairs while its dephosphorylation promotes interaction with FBXL2 and SCF(FBXL2)-mediated polyubiquitination.PTM Ubiquitinated. Polyubiquitination by the SCF(FBXL2) complex probably promotes proteasomal degradation of PIK3R2.SIMILARITY Belongs to the PI3K p85 subunit family.UniProtQ637881EQUAL728EQUALReactome Database ID Release 759826578Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9826578ReactomeR-RNO-747911Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-74791.1Pik3r3PIK3R3Q63789Reactome DB_ID: 9830054UniProt:Q63789Pik3r3UniProtQ637891EQUAL461EQUALReactome Database ID Release 759830054Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830054ReactomeR-RNO-2052231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-205223.1Reactome Database ID Release 759830056Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830056ReactomeR-RNO-3913421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-391342.11Reactome Database ID Release 759830058Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830058ReactomeR-RNO-1983791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-198379.1G-protein alpha (q/11):PI3K alphaReactome DB_ID: 985324011Reactome Database ID Release 759853240Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853240ReactomeR-RNO-4163561Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416356.1Reactome Database ID Release 759853242Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853242ReactomeR-RNO-4163581Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-416358.1Phospholipase C activation is the classical signalling route for G alpha (q) but an additional mechanism is an inhibitory interaction between G alpha (q) and phosphatidylinositol 3-kinase alpha (PI3K alpha). There are several PI3K subtypes but only the p85 alpha/p110 alpha subtype (PI3K alpha) is a G alpha (q) effector (PMID: 18515384). Activated G alpha (q) inhibits PI3K alpha directly, in a GTP-dependent manner. G alpha(q) binding of PI3K competes with Ras, a PI3K activator (PMID: 16268778).16268778Pubmed2006Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces RasBallou, LMChattopadhyay, MLi, YScarlata, SLin, RZBiochem J 394:557-6218515384Pubmed2008Galphaq binds two effectors separately in cells: evidence for predetermined signaling pathwaysGolebiewska, UScarlata, SBiophys J 95:2575-82LEFT-TO-RIGHT3.6.5.43.6.5.33.6.5.23.6.5.1G alpha (q) auto-inactivates by hydrolysing GTP to GDPThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>ACTIVATIONGENE ONTOLOGYGO:0003924Reactome Database ID Release 759853587Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853587Reactome Database ID Release 759853615Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853615ReactomeR-RNO-4185821Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418582.1When a ligand activates a G protein-coupled receptor, it induces a conformational change in the receptor (a change in shape) that allows the receptor to function as a guanine nucleotide exchange factor (GEF), stimulating the exchange of GDP for GTP on the G alpha subunit. In the traditional view of heterotrimeric protein activation, this exchange triggers the dissociation of the now active G alpha subunit from the beta:gamma dimer, initiating downstream signalling events. The G alpha subunit has intrinsic GTPase activity and will eventually hydrolyze the attached GTP to GDP, allowing reassociation with G beta:gamma. Additional GTPase-activating proteins (GAPs) stimulate the GTPase activity of G alpha, leading to more rapid termination of the transduced signal. In some cases the downstream effector may have GAP activity, helping to deactivate the pathway. This is the case for phospholipase C beta, which possesses GAP activity within its C-terminal region (Kleuss et al. 1994).7937899Pubmed1994Mechanism of GTP hydrolysis by G-protein alpha subunitsKleuss, CRaw, ASLee, ESprang, SRGilman, AGProc Natl Acad Sci U S A 91:9828-31ACTIVATIONReactome Database ID Release 759853616Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853616Converted from EntitySet in ReactomeRGS proteins active for G alpha (q)Reactome DB_ID: 9853613Rgs2RGS2Q9JHX0Reactome DB_ID: 9853591UniProt:Q9JHX0Rgs2UniProtQ9JHX01EQUAL211EQUALReactome Database ID Release 759853591Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853591ReactomeR-RNO-9397871Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-939787.1Rgs19RGS19O70521Reactome DB_ID: 9853595UniProt:O70521Rgs19UniProtO705211EQUAL217EQUALReactome Database ID Release 759853595Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853595ReactomeR-RNO-9211291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-921129.1Rgs18RGS18Q4L0E8Reactome DB_ID: 9853599UniProt:Q4L0E8Rgs18UniProtQ4L0E81EQUAL235EQUALReactome Database ID Release 759853599Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853599ReactomeR-RNO-9397991Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-939799.1Rgs3RGS3P49797Reactome DB_ID: 9853603UniProt:P49797Rgs3UniProtP497971EQUAL1198EQUALReactome Database ID Release 759853603Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853603ReactomeR-RNO-88494101Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-8849410.1Rgs21RGS21A0A0G2JZN6Reactome DB_ID: 9853607UniProt:A0A0G2JZN6Rgs21UniProtA0A0G2JZN61EQUAL152EQUALReactome Database ID Release 759853607Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853607ReactomeR-RNO-9397761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-939776.1Rgsl1RGSL1F1M608Reactome DB_ID: 9853611UniProt:F1M608Rgsl1UniProtF1M6081EQUAL1076EQUALReactome Database ID Release 759853611Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853611ReactomeR-RNO-88716111Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-8871611.1Reactome Database ID Release 759853613Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9853613ReactomeR-RNO-9211231Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-921123.1Effects of PIP2 hydrolysisThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>LEFT-TO-RIGHTBinding of IP3 to IP3 receptorThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>IP3I(1,4,5)P31D-myo-inositol 1,4,5-trisphosphateD-myo-Inositol 1,4,5-trisphosphateInositol 1,4,5-trisphosphatephosphatidylinositol 1,4,5-trisphosphateReactome DB_ID: 1145201D-myo-inositol 1,4,5-trisphosphate [ChEBI:16595]1D-myo-inositol 1,4,5-trisphosphateChEBICHEBI:16595Reactome Database ID Release 75114520Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114520ReactomeR-ALL-1145203Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114520.3COMPOUNDC01245IP3R tetramerReactome DB_ID: 9830431platelet dense tubular network membraneGENE ONTOLOGYGO:0031095Converted from EntitySet in ReactomeIP3R subunitsReactome DB_ID: 9830429Itpr2ITPR2P29995Reactome DB_ID: 9830421UniProt:P29995 Itpr2Itpr2FUNCTION Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).SUBUNIT Homotetramer (PubMed:12032348). Interacts with CABP1 (PubMed:12032348). Interacts with BOK; regulates ITPR2 expression (PubMed:23884412). Interacts with BCL2L10 (By similarity).DOMAIN The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.PTM Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.SIMILARITY Belongs to the InsP3 receptor family.UniProtP299951EQUAL2701EQUALReactome Database ID Release 759830421Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830421ReactomeR-RNO-4182811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418281.1Itpr3ITPR3Q63269Reactome DB_ID: 9830424UniProt:Q63269 Itpr3Itpr3FUNCTION Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.SUBUNIT Homotetramer. Interacts with TRPC1, TRPC3, TRPC4. Interacts with TRPV4 (By similarity). Interacts with SIGMAR1 (PubMed:11149946). Interacts with AKT1 and PML. Interacts with IRAG2 (via coiled-coil domain) (By similarity). Interacts with CABP1 (PubMed:12032348). Interacts with TMBIM4/LFG4 (By similarity). Interacts with CEMIP (By similarity). Interacts with TESPA1 (By similarity). Interacts with TMEM203 (By similarity). Interacts with BOK; regulates ITPR3 expression (PubMed:23884412). Interacts with BCL2L10 (By similarity).DOMAIN The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.PTM Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues (By similarity).SIMILARITY Belongs to the InsP3 receptor family.UniProtQ632691EQUAL2671EQUALReactome Database ID Release 759830424Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830424ReactomeR-RNO-4182831Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418283.1Itpr1ITPR1P29994Reactome DB_ID: 9830427UniProt:P29994 Itpr1Itpr1Insp3rFUNCTION Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.SUBUNIT Homotetramer. Interacts with TRPC4. The PPXXF motif binds HOM1, HOM2 and HOM3. Interacts with RYR1, RYR2, ITPR1, SHANK1 and SHANK3. Interacts with ERP44 in a pH-, redox state- and calcium-dependent manner which results in the inhibition the calcium channel activity. The strength of this interaction inversely correlates with calcium concentration. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1. Interacts with IRAG1 and CABP1 (via N-terminus). Interacts with TESPA1. Interacts (when not phosphorylated) with AHCYL1 (when phosphorylated); the interaction suppresses inositol 1,4,5-trisphosphate binding to ITPR1 and is increased in the presence of BCL2L10. Interacts with AHCYL2 (with lower affinity than with AHCYL1) (By similarity). Interacts with BCL2L10; the interaction is increased in the presence of AHCLY1 (By similarity). Interacts with BOK (via BH4. domain); protects ITPR1 from proteolysis by CASP3 during apoptosis (By similarity).TISSUE SPECIFICITY Isoform 3 is found in the brain while isoform 7 is found in the fetal brain and peripheral tissues.DOMAIN The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.PTM Phosphorylated by cAMP kinase (PKA). Phosphorylation prevents the ligand-induced opening of the calcium channels. Phosphorylation by PKA increases the interaction with inositol 1,4,5-trisphosphate and decreases the interaction with AHCYL1.PTM Phosphorylated on tyrosine residues.PTM Ubiquitination at multiple lysines targets ITPR1 for proteasomal degradation. Approximately 40% of the ITPR1-associated ubiquitin is monoubiquitin, and polyubiquitins are both 'Lys-48'- and 'Lys-63'-linked.PTM Palmitoylated by ZDHHC6 in immune cells, leading to regulate ITPR1 stability and function.MISCELLANEOUS Calcium appears to inhibit ligand binding to the receptor, most probably by interacting with a distinct calcium-binding protein which then inhibits the receptor.SIMILARITY Belongs to the InsP3 receptor family.UniProtP299941EQUAL2758EQUALReactome Database ID Release 759830427Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830427ReactomeR-RNO-33255931Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-3325593.1Reactome Database ID Release 759830429Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830429ReactomeR-RNO-4182841Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418284.14Reactome Database ID Release 759830431Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830431ReactomeR-RNO-4182921Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-418292.1IP3R tetramer:I(1,4,5)P3:4xCa2+Reactome DB_ID: 9830433Ca2+Calciumcalcium(2+)Reactome DB_ID: 141090Reactome Database ID Release 75141090Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=141090ReactomeR-ALL-1410903Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-141090.3COMPOUNDC000764I(1,4,5)P31D-myo-inositol 1,4,5-trisphosphateReactome DB_ID: 139826Reactome Database ID Release 75139826Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=139826ReactomeR-ALL-1398263Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-139826.3COMPOUNDC0124541Reactome Database ID Release 759830433Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830433ReactomeR-RNO-1398391Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-139839.1Reactome Database ID Release 759830581Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830581ReactomeR-RNO-1399411Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-139941.1The IP3 receptor (IP3R) is an intracellular calcium release channel that mobilizes Ca2+ from internal stores in the ER to the cytoplasm. Though its activity is stimulated by IP3, the principal activator of the IP3R is Ca2+. This process of calcium-induced calcium release is central to the mechanism of Ca2+ signalling. The effect of cytosolic Ca2+ on IP3R is complex: it can be both stimulatory and inhibitory and can the effect varies between IP3R isoforms. In general, the IP3Rs have a bell-shaped Ca2+ dependence when treated with low concentrations of IP3; low concentrations of Ca2+ (100–300 nM) are stimulatory but above 300 nM, Ca2+ becomes inhibitory and switches the channel off. The stimulatory effect of IP3 is to relieve Ca2+ inhibition of the channel, enabling Ca2+ activation sites to gate it. <br>Functionally the IP3 receptor is believed to be tetrameric, with results indicating that the tetramer is composed of 2 pairs of protein isoforms.17429043Pubmed2007Inositol trisphosphate receptor Ca2+ release channelsFoskett, JKWhite, CCheung, KHMak, DOPhysiol Rev 87:593-65811413485Pubmed2000The versatility and universality of calcium signallingBerridge, MJLipp, PBootman, MDNat Rev Mol Cell Biol 1:11-21LEFT-TO-RIGHTTransport of Ca++ from platelet dense tubular system to cytoplasmIP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosolThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Ca2+Calciumcalcium(2+)Reactome DB_ID: 139827platelet dense tubular network lumenGENE ONTOLOGYGO:0031096Reactome Database ID Release 75139827Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=139827ReactomeR-ALL-1398273Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-139827.3COMPOUNDC00076Ca2+Calciumcalcium(2+)Reactome DB_ID: 74016Reactome Database ID Release 7574016Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=74016ReactomeR-ALL-740163Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-74016.3COMPOUNDC00076ACTIVATIONGENE ONTOLOGYGO:0005262Reactome Database ID Release 759830434Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830434Reactome Database ID Release 759830436Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9830436ReactomeR-RNO-1398541Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-139854.1The IP3 receptor (IP3R) is an intracellular calcium release channel that mobilizes Ca2+ from internal stores in the ER to the cytoplasm. Though its activity is stimulated by IP3, the principal activator of the IP3R is Ca2+. This process of calcium-induced calcium release is central to the mechanism of Ca2+ signalling. The effect of cytosolic Ca2+ on IP3R is complex: it can be both stimulatory and inhibitory and can the effect varies between IP3R isoforms. In general, the IP3Rs have a bell-shaped Ca2+ dependence when treated with low concentrations of IP3; low concentrations of Ca2+ (100–300 nM) are stimulatory but above 300 nM, Ca2+ becomes inhibitory and switches the channel off. The stimulatory effect of IP3 is to relieve Ca2+ inhibition of the channel, enabling Ca2+ activation sites to gate it. <br>Functionally the IP3 receptor is believed to be tetrameric, with results indicating that the tetramer is composed of 2 pairs of protein isoforms.1693919Pubmed1990Receptor-activated single channels in intact human plateletsMahaut-Smith, MPSage, SORink, TJJ Biol Chem 265:10479-83LEFT-TO-RIGHTActivation of Protein Kinase C novel isoformsThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Converted from EntitySet in ReactomeProtein kinase C, novel isoformsProtein Kinase C, unconventional isoformsReactome DB_ID: 9854680PrkcdPRKCDP09215Reactome DB_ID: 9829417UniProt:P09215PrkcdUniProtP092151EQUAL676EQUALReactome Database ID Release 759829417Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9829417ReactomeR-RNO-582001Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-58200.1PrkcePRKCEP09216Reactome DB_ID: 9839776UniProt:P09216PrkceUniProtP092161EQUAL737EQUALReactome Database ID Release 759839776Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9839776ReactomeR-RNO-582021Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-58202.1PrkchPRKCHQ64617Reactome DB_ID: 9854678UniProt:Q64617PrkchUniProtQ646171EQUAL683EQUALReactome Database ID Release 759854678Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854678ReactomeR-RNO-582081Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-58208.1PrkcqPRKCQQ9WTQ0Reactome DB_ID: 9841436UniProt:Q9WTQ0PrkcqUniProtQ9WTQ01EQUAL706EQUALReactome Database ID Release 759841436Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9841436ReactomeR-RNO-582161Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-58216.1Reactome Database ID Release 759854680Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854680ReactomeR-RNO-4258501Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-425850.1DAG1,2-Diacylglycerol1,2-diacyl-sn-glycerolReactome DB_ID: 1145191,2-diacyl-sn-glycerol [ChEBI:17815]1,2-diacyl-sn-glycerolChEBICHEBI:17815Reactome Database ID Release 75114519Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114519ReactomeR-ALL-1145194Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-114519.4Protein kinase C, novel isoforms:DAGReactome DB_ID: 985468211Reactome Database ID Release 759854682Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854682ReactomeR-RNO-4260711Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426071.1Reactome Database ID Release 759854684Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854684ReactomeR-RNO-4258611Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-425861.1Activation of the novel Protein Kinase C (nPKC) isoforms (delta, epsilon, eta and theta) requires binding to the membrane lipid diacylglycerol (DAG). nPKC activation is sensitive to DAG concentration.9601053Pubmed1998The extended protein kinase C superfamilyMellor, HParker, PJBiochem J 332:281-9219033211Pubmed2009Lipid activation of protein kinasesNewton, ACJ Lipid Res 50:S266-719780306478635ISBN2004Protein Kinase C 2nd edDekker, LProtein Kinase C 2nd ed (Book)LEFT-TO-RIGHTDAG activation of TRPC channelsThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Converted from EntitySet in ReactomeTRPC3/6/7Reactome DB_ID: 9854804Trpc3TRPC3(1-848)Q9JMI9Reactome DB_ID: 9854794UniProt:Q9JMI9Trpc3UniProtQ9JMI91EQUAL848EQUALReactome Database ID Release 759854794Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854794ReactomeR-RNO-4261721Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426172.1Trpc7TRPC7F1LQF7Reactome DB_ID: 9854798UniProt:F1LQF7Trpc7UniProtF1LQF71EQUAL862EQUALReactome Database ID Release 759854798Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854798ReactomeR-RNO-4261711Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426171.1Trpc6TRPC6Q99N78Reactome DB_ID: 9854802UniProt:Q99N78Trpc6UniProtQ99N781EQUAL931EQUALReactome Database ID Release 759854802Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854802ReactomeR-RNO-12973241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-1297324.1Reactome Database ID Release 759854804Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854804ReactomeR-RNO-4261761Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426176.1DAG-activated TRPC3/6/7Reactome DB_ID: 985480611Reactome Database ID Release 759854806Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854806ReactomeR-RNO-4261791Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426179.1Reactome Database ID Release 759854808Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854808ReactomeR-RNO-4262091Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426209.1TRPC3, 6 and 7 are non-selective cation channels that are activated by diacylglycerol (DAG) independently of protein kinase C activation by DAG. By analogy with the structures of voltage-regulated calcium channels, TRPC channels are probably tetramers of TRPC protein; heterotetramers within the 3/6/7 group have been observed.10488066Pubmed1999Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptorOkada, TInoue, RYamazaki, KMaeda, AKurosaki, TYamakuni, TTanaka, IShimizu, SIkenaka, KImoto, KMori, YJ Biol Chem 274:27359-708986787Pubmed1996On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteinsBirnbaumer, LZhu, XJiang, MBoulay, GPeyton, MVannier, BBrown, DPlatano, DSadeghi, HStefani, EBirnbaumer, MProc Natl Acad Sci U S A 93:15195-20212765690Pubmed2003The TRPC3/6/7 subfamily of cation channelsTrebak, MVazquez, GBird, GSPutney JW, JrCell Calcium 33:451-619930701Pubmed1999Direct activation of human TRPC6 and TRPC3 channels by diacylglycerolHofmann, TObukhov, AGSchaefer, MHarteneck, CGudermann, TSchultz, GNature 397:259-6312032305Pubmed2002Subunit composition of mammalian transient receptor potential channels in living cellsHofmann, TSchaefer, MSchultz, GGudermann, TProc Natl Acad Sci U S A 99:7461-611805119Pubmed2002Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influxRiccio, AMattei, CKelsell, REMedhurst, ADCalver, ARRandall, ADDavis, JBBenham, CDPangalos, MNJ Biol Chem 277:12302-9Arachidonate production from DAGThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>LEFT-TO-RIGHT3.1.1.23DAG is metabolized by DAGL to 2-AGThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Fatty AcidReactome DB_ID: 426026fatty acid [ChEBI:35366]fatty acidChEBICHEBI:35366Reactome Database ID Release 75426026Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426026ReactomeR-ALL-4260262Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-426026.22AG2-AG2-arachidonoylglycerolReactome DB_ID: 4260302-arachidonoylglycerol [ChEBI:52392]2-arachidonoylglycerolChEBICHEBI:52392Reactome Database ID Release 75426030Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426030ReactomeR-ALL-4260303Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-426030.3COMPOUNDC13856ACTIVATIONConverted from EntitySet in ReactomeDiacylglycerol lipaseReactome DB_ID: 9854740DaglaDAGLAQ5YLM1Reactome DB_ID: 9854734UniProt:Q5YLM1DaglaUniProtQ5YLM11EQUAL1042EQUALReactome Database ID Release 759854734Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854734ReactomeR-RNO-4260221Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426022.1DaglbDAGLBP0C1S9Reactome DB_ID: 9854738UniProt:P0C1S9DaglbUniProtP0C1S91EQUAL672EQUALReactome Database ID Release 759854738Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854738ReactomeR-RNO-4260201Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426020.1Reactome Database ID Release 759854740Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854740ReactomeR-RNO-4260241Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426024.1GENE ONTOLOGYGO:0047372Reactome Database ID Release 759854741Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854741Reactome Database ID Release 759854743Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9854743ReactomeR-RNO-4260321Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-RNO-426032.1Diacylglycerol lipase (DAGL) hydrolyzes diacylglycerol (DAG) at the sn-1 position, producing 2-monoacylglycerols, including 2-arachidonlyglycerol (2-AG) and free fatty acid. This reaction was first characterised for the release of arachidonate from membrane phospholipids in platelets, but is also involved in the spatial and temporal regulation of endocannabinoid signaling in the brain. DAGL exhibits strong selectivity for diacylglycerols over phospholipids, monoacylglycerols, triacylglycerols and fatty acid amides, and prefers the acyl group at sn-1 position to that at sn-2.19126434Pubmed2008Biology of endocannabinoid synthesis systemWang, JUeda, NProstaglandins Other Lipid Mediat10348910Pubmed1999Purification and characterization of diacylglycerol lipase from human plateletsMoriyama, TUrade, RKito, MJ Biochem 125:1077-85LEFT-TO-RIGHT