BioPAX pathway converted from "Association of Securin with Cdc20:APC/C complex" in the Reactome database.LEFT-TO-RIGHTAssociation of Securin with Cdc20:APC/C complexThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>PTTG1PTTG1E2RRF2Reactome DB_ID: 9946474cytosolGENE ONTOLOGYGO:0005829UniProt:E2RRF2PTTG1Canis familiarisNCBI Taxonomy9615UniProtE2RRF21EQUAL202EQUALReactome Database ID Release 759946474Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946474ReactomeR-CFA-1741901Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174190.1Reactomehttp://www.reactome.orgCDC20:p-APC/CReactome DB_ID: 9946519CDC20CDC20E2RGS2Reactome DB_ID: 9943024UniProt:E2RGS2CDC20UniProtE2RGS21EQUAL499EQUALReactome Database ID Release 759943024Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9943024ReactomeR-CFA-1414121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-141412.11phosphorylated anaphase promoting complex (APC/C)Reactome DB_ID: 9934269CDC26CDC26J9P4C8Reactome DB_ID: 9934239UniProt:J9P4C8CDC26UniProtJ9P4C81EQUAL85EQUALReactome Database ID Release 759934239Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934239ReactomeR-CFA-1740521Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174052.11E2R4W0ANAPC11ANAPC11Reactome DB_ID: 9934255UniProt:E2R4W0ANAPC11UniProtE2R4W01EQUAL84EQUALReactome Database ID Release 759934255Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934255ReactomeR-CFA-1741261Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174126.11UBE2E1UBE2E1E2QXE6Reactome DB_ID: 9934243UniProt:E2QXE6UBE2E1UniProtE2QXE62EQUAL193EQUALReactome Database ID Release 759934243Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934243ReactomeR-CFA-1741001Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174100.11CDC16CDC16E2R5H6Reactome DB_ID: 9934227UniProt:E2R5H6CDC16UniProtE2R5H61EQUAL620EQUALReactome Database ID Release 759934227Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934227ReactomeR-CFA-1741561Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174156.11CDC23CDC23E2RHG6Reactome DB_ID: 9934235UniProt:E2RHG6CDC23UniProtE2RHG61EQUAL597EQUALReactome Database ID Release 759934235Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934235ReactomeR-CFA-1741371Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174137.11E2RKJ5ANAPC16ANAPC16Reactome DB_ID: 9934263UniProt:E2RKJ5ANAPC16UniProtE2RKJ52EQUAL110EQUALReactome Database ID Release 759934263Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934263ReactomeR-CFA-68051381Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-6805138.11UBE2SUBE2SJ9PAH6Reactome DB_ID: 9934267UniProt:J9PAH6UBE2SUniProtJ9PAH61EQUAL222EQUALReactome Database ID Release 759934267Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934267ReactomeR-CFA-9476221Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-947622.11UBE2D1UBE2D1J9NTA2Reactome DB_ID: 9934251UniProt:J9NTA2UBE2D1UniProtJ9NTA21EQUAL147EQUALReactome Database ID Release 759934251Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934251ReactomeR-CFA-1742361Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174236.11E2QWL6ANAPC15ANAPC15Reactome DB_ID: 9934259UniProt:E2QWL6ANAPC15UniProtE2QWL61EQUAL121EQUALReactome Database ID Release 759934259Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934259ReactomeR-CFA-68051401Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-6805140.11ANAPC4ANAPC4E2R8L6Reactome DB_ID: 9934219UniProt:E2R8L6ANAPC4UniProtE2R8L61EQUAL808EQUALReactome Database ID Release 759934219Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934219ReactomeR-CFA-1741681Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174168.11ANAPC1ANAPC1E2RLM2Reactome DB_ID: 9934203UniProt:E2RLM2ANAPC1UniProtE2RLM21EQUAL1944EQUALReactome Database ID Release 759934203Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934203ReactomeR-CFA-1741891Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174189.11ANAPC2ANAPC2F1PYP1Reactome DB_ID: 9934211UniProt:F1PYP1ANAPC2UniProtF1PYP11EQUAL822EQUALReactome Database ID Release 759934211Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934211ReactomeR-CFA-1742291Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174229.11UBE2CUBE2CE2RN95Reactome DB_ID: 9934247UniProt:E2RN95UBE2CUniProtE2RN952EQUAL179EQUALReactome Database ID Release 759934247Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934247ReactomeR-CFA-1742441Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174244.11CDC27CDC27F1Q3E7Reactome DB_ID: 9934215UniProt:F1Q3E7CDC27UniProtF1Q3E71EQUAL824EQUALReactome Database ID Release 759934215Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934215ReactomeR-CFA-1740731Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174073.11ANAPC5ANAPC5E2R4S0Reactome DB_ID: 9934223UniProt:E2R4S0ANAPC5UniProtE2R4S01EQUAL755EQUALReactome Database ID Release 759934223Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934223ReactomeR-CFA-1742111Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174211.11E2R745ANAPC10ANAPC10Reactome DB_ID: 9934207UniProt:E2R745ANAPC10UniProtE2R7451EQUAL185EQUALReactome Database ID Release 759934207Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934207ReactomeR-CFA-1741421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174142.11ANAPC7ANAPC7E2R9A5Reactome DB_ID: 9934231UniProt:E2R9A5ANAPC7UniProtE2R9A51EQUAL599EQUALReactome Database ID Release 759934231Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934231ReactomeR-CFA-1742421Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174242.11Reactome Database ID Release 759934269Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9934269ReactomeR-CFA-1741911Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174191.11Reactome Database ID Release 759946519Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946519ReactomeR-CFA-1740811Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174081.1CDC20:p-APC/C:PTTG1Reactome DB_ID: 994652511Reactome Database ID Release 759946525Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946525ReactomeR-CFA-1742121Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174212.1Reactome Database ID Release 759946527Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9946527ReactomeR-CFA-1741211Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-174121.1Securin is thought to be recognized by the APC/C:Cdc20 complex through its conserved D-box sequence.12070128Pubmed2002Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1Hagting, ADen Elzen, NVodermaier, HCWaizenegger, ICPeters, JMPines, JJ Cell Biol 157:1125-37inferred from electronic annotationEVIDENCE CODEECO:0000203