Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Xu, Wanping (1227984)

DB_ID Name
1227986 Signaling by ERBB2
1250196 SHC1 events in ERBB2 signaling
1251932 PLCG1 events in ERBB2 signaling
1306955 GRB7 events in ERBB2 signaling
1358803 Downregulation of ERBB2:ERBB3 signaling
1963640 GRB2 events in ERBB2 signaling
1963642 PI3K events in ERBB2 signaling

Details on Person Xu, Wanping

_displayNameXu, Wanping
_timestamp2017-08-22 20:38:20
affiliation[Affiliation:1972348] National Cancer Institute (NCI)
created[InstanceEdit:1227973] Orlic-Milacic, Marija, 2011-03-15
modified[InstanceEdit:1972350] Orlic-Milacic, M, 2011-11-04
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:1972346] Xu, W, 2011-11-11
[LiteratureReference:1227977] Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90
[LiteratureReference:1227978] Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex
[LiteratureReference:1810436] Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity
[LiteratureReference:1916707] Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu
[LiteratureReference:1918078] Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase
[LiteratureReference:2008136] Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition
[LiteratureReference:8874501] Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
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