Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Earp HS, H. Shelton (1253276)

DB_ID Name
1236394 Signaling by ERBB4
1250342 PI3K events in ERBB4 signaling
1250347 SHC1 events in ERBB4 signaling
1251985 Nuclear signaling by ERBB4
1253288 Downregulation of ERBB4 signaling

Details on Person Earp HS, H. Shelton

_displayNameEarp HS, H. Shelton
_timestamp2017-08-22 20:38:57
affiliation[Affiliation:2104981] Lineberger Comprehensive Cancer Center
[Affiliation:74577] University of North Carolina at Chapel Hill
created[InstanceEdit:1253298] Orlic-Milacic, Marija, 2011-04-27
firstnameH. Shelton
modified[InstanceEdit:2104983] Orlic-Milacic, M, 2012-02-08
[InstanceEdit:2161170] Orlic-Milacic, M, 2012-03-08
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
surnameEarp HS
(author)[InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20
[LiteratureReference:1253295] The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation
[LiteratureReference:1254297] Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation
[LiteratureReference:2029515] ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo
[LiteratureReference:2029517] Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1
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