Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Matthews, Lisa (142011)

DB_ID Name
73884 Base Excision Repair
73894 DNA Repair
73927 Depurination
73929 Base-Excision Repair, AP Site Formation
73928 Depyrimidination
73930 Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
73933 Resolution of Abasic Sites (AP sites)
75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
109606 Intrinsic Pathway for Apoptosis
110329 Cleavage of the damaged pyrimidine
110328 Recognition and association of DNA glycosylase with site containing an affected pyrimidine
110331 Cleavage of the damaged purine
110330 Recognition and association of DNA glycosylase with site containing an affected purine
110357 Displacement of DNA glycosylase by APEX1
110362 POLB-Dependent Long Patch Base Excision Repair
110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway
110381 Resolution of AP sites via the single-nucleotide replacement pathway
111457 Release of apoptotic factors from the mitochondria
111461 Cytochrome c-mediated apoptotic response
111469 SMAC-mediated apoptotic response
140342 Apoptosis induced DNA fragmentation
156827 L13a-mediated translational silencing of Ceruloplasmin expression
162587 HIV Life Cycle
162906 HIV Infection
165054 Rev-mediated nuclear export of HIV RNA
2262752 Cellular responses to stress
167152 Formation of HIV elongation complex in the absence of HIV Tat
167158 Formation of the HIV-1 Early Elongation Complex
167162 RNA Polymerase II HIV Promoter Escape
167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
167161 HIV Transcription Initiation
167169 HIV Transcription Elongation
167172 Transcription of the HIV genome
167200 Formation of HIV-1 elongation complex containing HIV-1 Tat
176034 Interactions of Tat with host cellular proteins
176033 Interactions of Vpr with host cellular proteins
177243 Interactions of Rev with host cellular proteins
180534 Vpu mediated degradation of CD4
180585 Vif-mediated degradation of APOBEC3G
180689 APOBEC3G mediated resistance to HIV-1 infection
180746 Nuclear import of Rev protein
180897 Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
180910 Vpr-mediated nuclear import of PICs
211227 Activation of DNA fragmentation factor
349425 Autodegradation of the E3 ubiquitin ligase COP1
380259 Loss of Nlp from mitotic centrosomes
380270 Recruitment of mitotic centrosome proteins and complexes
380284 Loss of proteins required for interphase microtubule organization from the centrosome
380287 Centrosome maturation
380320 Recruitment of NuMA to mitotic centrosomes
389957 Prefoldin mediated transfer of substrate to CCT/TriC
389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
389960 Formation of tubulin folding intermediates by CCT/TriC
389977 Post-chaperonin tubulin folding pathway
390450 Folding of actin by CCT/TriC
390471 Association of TriC/CCT with target proteins during biosynthesis
390466 Chaperonin-mediated protein folding
391251 Protein folding
392499 Metabolism of proteins
418990 Adherens junctions interactions
420029 Tight junction interactions
420597 Nectin/Necl trans heterodimerization
421270 Cell-cell junction organization
446107 Type I hemidesmosome assembly
446343 Localization of the PINCH-ILK-PARVIN complex to focal adhesions
446353 Cell-extracellular matrix interactions
446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
5693537 Resolution of D-Loop Structures
5693548 Sensing of DNA Double Strand Breaks
5693568 Resolution of D-loop Structures through Holliday Junction Intermediates
5693579 Homologous DNA Pairing and Strand Exchange
6783310 Fanconi Anemia Pathway
774815 Nucleosome assembly
1852241 Organelle biogenesis and maintenance

Pathways reviewed by Matthews, Lisa (142011)

DB_ID Name
5334727 Mus musculus biological processes
212165 Epigenetic regulation of gene expression
264876 Insulin processing
380994 ATF4 activates genes
381038 XBP1(S) activates chaperone genes
381033 ATF6 (ATF6-alpha) activates chaperones
381042 PERK regulates gene expression
381070 IRE1alpha activates chaperones
381119 Unfolded Protein Response (UPR)
381183 ATF6 (ATF6-alpha) activates chaperone genes
381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
382551 Transport of small molecules
382556 ABC-family proteins mediated transport
8863795 Downregulation of ERBB2 signaling
1799339 SRP-dependent cotranslational protein targeting to membrane
1852241 Organelle biogenesis and maintenance

Details on Person Matthews, Lisa

_displayNameMatthews, Lisa
_timestamp2017-08-22 20:37:39
affiliation[Affiliation:158007] Cold Spring Harbor Laboratory
created[InstanceEdit:142010] Matthews, L, 2004-10-21 02:50:50
crossReference[DatabaseIdentifier:5357625] ORCID:0000-0001-5707-3065
modified[InstanceEdit:164739] Matthews, L, 2005-06-16 19:52:54
[InstanceEdit:180183] D'Eustachio, P, 2006-05-16 19:02:32
[InstanceEdit:190443] Matthews, L, 2007-01-09 07:29:20
[InstanceEdit:5173293] Matthews, Lisa, 2013-11-25
[InstanceEdit:5357626] Rothfels, Karen, 2014-03-25
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:73902] Hoeijmakers, JH, Lees-Miller, S, Thompson, L, Gopinathrao, G, Matthews, L, Schultz, R, Pegg, A, 2003-07-10 00:12:38
[InstanceEdit:74384] Matthews, L, 0000-00-00 00:00:00
[InstanceEdit:75002] Matthews, L, 2003-08-05 01:10:00
[InstanceEdit:75039] Matthews, L, 2003-08-08 06:25:00
[InstanceEdit:75046] Matthews, L, 2003-08-08 02:54:00
[InstanceEdit:75141] Matthews, L, 2003-08-11 05:43:00
[InstanceEdit:75804] Matthews, L, 2003-09-01 04:23:00
[InstanceEdit:75842] Matthews, L, 2003-09-05 00:04:00
[InstanceEdit:75904] Matthews, L, 2003-09-07 08:47:00
[InstanceEdit:75992] Matthews, L, 2003-09-10 06:00:00
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