Reactome: A Curated Pathway Database

Query author contributions in Reactome

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Pathways authored by Yen, Tim (143446)

DB_ID Name
69620 Cell Cycle Checkpoints
69618 Mitotic Spindle Checkpoint
141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
141424 Amplification of signal from the kinetochores
141430 Inactivation of APC/C via direct inhibition of the APC/C complex
141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

Details on Person Yen, Tim

_displayNameYen, Tim
_timestamp2017-08-22 20:37:40
affiliation[Affiliation:157520] Fox Chase Cancer Center - University of Pennsylvania
created[InstanceEdit:143429] Matthews, L, 2004-11-09 23:52:37
modified[InstanceEdit:157521] Joshi-Tope, G, 2005-01-01 01:03:58
[InstanceEdit:5173327] Matthews, Lisa, 2013-11-27
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[LiteratureReference:143441] Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase
[LiteratureReference:143450] Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
[LiteratureReference:143454] The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit
[LiteratureReference:377675] Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells
[LiteratureReference:377735] CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells
[LiteratureReference:984613] CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase
[InstanceEdit:69619] Hoffmann, I, Khanna, KK, Walworth, N, Yen, Tim, O'Donnell, M, 2005-01-01
[InstanceEdit:143430] Yen, T, 2004-05-05 00:00:00
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