Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Avruch, Joseph (165700)

DB_ID Name
2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7

Details on Person Avruch, Joseph

Class:IdPerson:165700
_displayNameAvruch, Joseph
_timestamp2017-08-22 20:37:59
affiliation[Affiliation:918087] Harvard Medical School
created[InstanceEdit:165688] de Bono, B, 2005-08-09 10:31:29
firstnameJoseph
initialJ
modified[InstanceEdit:2028253] D'Eustachio, P, 2011-12-26
[InstanceEdit:3132747] Orlic-Milacic, M, 2013-02-12
[InstanceEdit:6793048] Matthews, Lisa, 2015-08-28
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
surnameAvruch
(author)[InstanceEdit:3132746] Avruch, Joseph, 2013-02-08
[LiteratureReference:165687] Raptor, a binding partner of target of rapamycin (TOR), mediates TOR
[LiteratureReference:208235] Phosphorylation of c-jun mediated by MAP kinases
[LiteratureReference:376999] Rheb binds and regulates the mTOR kinase
[LiteratureReference:377225] The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1
[LiteratureReference:500520] The stress-activated protein kinase subfamily of c-Jun kinases
[LiteratureReference:2028272] Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
[LiteratureReference:2028634] MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
[LiteratureReference:2980712] A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases
[LiteratureReference:2980764] Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression
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