Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Gay, Nicholas J (165841)

DB_ID Name
168179 Toll Like Receptor TLR1:TLR2 Cascade
168188 Toll Like Receptor TLR6:TLR2 Cascade
181438 Toll Like Receptor 2 (TLR2) Cascade
168898 Toll-Like Receptors Cascades

Pathways reviewed by Gay, Nicholas J (165841)

DB_ID Name
168256 Immune System
166016 Toll Like Receptor 4 (TLR4) Cascade
166020 Transfer of LPS from LBP carrier to CD14
166054 Activated TLR4 signalling
166058 MyD88:Mal cascade initiated on plasma membrane
166166 MyD88-independent TLR4 cascade
168164 Toll Like Receptor 3 (TLR3) Cascade
168180 TRAF6 Mediated Induction of proinflammatory cytokines
168927 TICAM1, RIP1-mediated IKK complex recruitment
168898 Toll-Like Receptors Cascades

Details on Person Gay, Nicholas J

_displayNameGay, Nicholas J
_timestamp2017-08-22 20:37:59
affiliation[Affiliation:1237412] University of Cambridge, Department of Biochemistry
created[InstanceEdit:165843] de Bono, B, 2005-08-11 14:55:53
firstnameNicholas J
modified[InstanceEdit:1237406] D'Eustachio, P, 2011-03-30
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:179395] D'Eustachio, P, Gay, NJ, Gale M, Jr, Zwaginga, JJ, 2006-04-19 04:09:58
[InstanceEdit:188947] de Bono, B, Gillespie, ME, Luo, F, Gay, NJ, 0000-00-00 00:00:00
[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17
[InstanceEdit:188964] D'Eustachio, P, Gale M, Jr, Gay, NJ, 2006-10-31 16:43:59
[LiteratureReference:165842] MD-2: the Toll 'gatekeeper' in endotoxin signalling
[LiteratureReference:208173] Binding of the Drosophila cytokine Spatzle to Toll is direct and establishes signaling
[LiteratureReference:208258] Structure and function of toll receptors and their ligands
[LiteratureReference:208281] Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway
[LiteratureReference:208301] Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand
[LiteratureReference:358180] Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle
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