Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Lorca, T (170233)

DB_ID Name
174048 APC/C:Cdc20 mediated degradation of Cyclin B
174084 Autodegradation of Cdh1 by Cdh1:APC/C
174113 SCF-beta-TrCP mediated degradation of Emi1
174143 APC/C-mediated degradation of cell cycle proteins
174154 APC/C:Cdc20 mediated degradation of Securin
174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
176417 Phosphorylation of Emi1
176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
179409 APC-Cdc20 mediated degradation of Nek2A
179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

Pathways reviewed by Lorca, T (170233)

DB_ID Name
69275 G2/M Transition

Details on Person Lorca, T

_displayNameLorca, T
_timestamp2017-08-22 20:38:05
affiliation[Affiliation:170242] Centre de Recherches de Biochimie Macromoleculaire
created[InstanceEdit:170184] Matthews, L, 2005-12-28 10:02:46
modified[InstanceEdit:2168071] Orlic-Milacic, M, 2012-03-23
(author)[InstanceEdit:170215] Lorca, T, 2005-10-10 00:00:00
[InstanceEdit:174241] Lorca, T, Castro, A, 2006-01-26 00:00:00
[InstanceEdit:188368] Lorca, T, Castro, A, 2006-10-10 10:03:43
[LiteratureReference:174118] The anaphase-promoting complex: a key factor in the regulation of cell cycle
[LiteratureReference:177093] The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A
[LiteratureReference:2168075] The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A
[LiteratureReference:2467588] Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance
[LiteratureReference:2506900] Characterization of the mechanisms controlling Greatwall activity
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