Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Skowronski, Jacek (182291)

DB_ID Name
164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
164939 Nef mediated downregulation of CD28 cell surface expression
164940 Nef mediated downregulation of MHC class I complex cell surface expression
164944 Nef and signal transduction
164952 The role of Nef in HIV-1 replication and disease pathogenesis
167590 Nef Mediated CD4 Down-regulation
182218 Nef Mediated CD8 Down-regulation

Details on Person Skowronski, Jacek

_displayNameSkowronski, Jacek
_timestamp2017-08-22 20:38:23
created[InstanceEdit:182282] Gillespie, ME, 2006-07-06 21:32:37
modified[InstanceEdit:200907] Gillespie, ME, 2007-07-25 21:01:05
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[LiteratureReference:182280] Mechanism for down-regulation of CD28 by Nef
[LiteratureReference:200827] Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
[LiteratureReference:200885] Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail
[LiteratureReference:200901] A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
[LiteratureReference:200934] HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis
[InstanceEdit:201388] Skowronski, J, 2007-08-07 14:33:41
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