Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Akkerman, Jan Willem N (199708)

DB_ID Name
392154 Nitric oxide stimulates guanylate cyclase
392517 Rap1 signalling
392518 Signal amplification
392851 Prostacyclin signalling through prostacyclin receptor
418346 Platelet homeostasis
418359 Reduction of cytosolic Ca++ levels
418360 Platelet calcium homeostasis
418457 cGMP effects
428930 Thromboxane signalling through TP receptor
430116 GP1b-IX-V activation signalling
432142 Platelet sensitization by LDL
456926 Thrombin signalling through proteinase activated receptors (PARs)
983189 Kinesins
983231 Factors involved in megakaryocyte development and platelet production

Pathways reviewed by Akkerman, Jan Willem N (199708)

DB_ID Name
388396 GPCR downstream signalling
392451 G beta:gamma signalling through PI3Kgamma
397795 G-protein beta:gamma signalling
416476 G alpha (q) signalling events
416482 G alpha (12/13) signalling events
418217 G beta:gamma signalling through PLC beta
418555 G alpha (s) signalling events
418597 G alpha (z) signalling events
418594 G alpha (i) signalling events
392023 Adrenaline signalling through Alpha-2 adrenergic receptor
392170 ADP signalling through P2Y purinoceptor 12
418592 ADP signalling through P2Y purinoceptor 1
426048 Arachidonate production from DAG

Details on Person Akkerman, Jan Willem N

_displayNameAkkerman, Jan Willem N
_timestamp2017-08-22 20:38:48
affiliation[Affiliation:1237441] University Medical Center Utrecht, Department of Clinical Chemistry and Haematology
created[InstanceEdit:199720] D'Eustachio, P, 2007-07-11 20:28:53
firstnameJan Willem N
modified[InstanceEdit:1237444] D'Eustachio, P, 2011-03-30
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[LiteratureReference:199700] Compartmentation of hexokinase in human blood cells. Characterization of soluble and particulate enzymes.
[LiteratureReference:420312] Site-specific phosphorylation of platelet focal adhesion kinase by low-density lipoprotein
[LiteratureReference:429167] The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
[LiteratureReference:432091] Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits low density lipoprotein-induced signaling in platelets
[LiteratureReference:432126] Binding of low density lipoprotein to platelet apolipoprotein E receptor 2' results in phosphorylation of p38MAPK
[LiteratureReference:432145] Platelet activation by the apoB/E receptor-binding domain of LDL
[LiteratureReference:443918] Thrombopoietin and platelet function
[LiteratureReference:1027304] Cyclic AMP raises intracellular Ca(2+) in human megakaryocytes independent of protein kinase A
[InstanceEdit:425201] Akkerman, JW, 2009-06-03
[InstanceEdit:435013] Akkerman, JW, 2009-09-04
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