Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Pathways reviewed by Lemaitre, B (207144)

DB_ID Name
209171 Peptidoglycans (PGN) bind to a peptidoglycan recognition protein receptor, PGRP-LC/LE
209266 Peptidoglycan bound PGRP-LC/LE oligomerises
209394 Transcriptional activtion and repression of REL-68 target genes
209397 Formation of the cytosolic BSK 'scaffolding complex'
209400 Transcriptional activtion by phosphorylated DL/DIF dimer
209406 Degradation of NF-kappa-B inhibitor, CACT
209409 Formation of the nuclear AP-1 transcription factor 'scaffolding complex'
209425 Transcriptional activtion by AP-1 transcription factor
209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex'
209442 Formation of the trans-membrane 'signalling complex'
209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY
209449 Toll pathway
209459 Imd pathway
209465 Catalytic processing of the nuclear factor, REL
209478 Dephosphorylation of BSK
214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'
214397 Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex'
214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'
214416 Phosphorylated REL is cleaved by and dissociates from DREDD
214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'
214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'
214863 Adaptor protein complex binds to TL receptor at the plasma membrane
214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex'
214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'
214874 PLL kinase binds to TUB in the TL receptor 'signalling complex'

Details on Person Lemaitre, B

_displayNameLemaitre, B
_timestamp2017-08-22 20:38:59
created[InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19
(author)[LiteratureReference:208069] The road to Toll
[LiteratureReference:208077] The host defense of Drosophila melanogaster
[LiteratureReference:208174] Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila
[LiteratureReference:208186] The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
[LiteratureReference:208251] Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway
[LiteratureReference:208297] The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection
[LiteratureReference:208355] A Spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity
[LiteratureReference:208372] A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
[LiteratureReference:208394] Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
[LiteratureReference:214843] In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila
List all 21 refering instances
[Change default viewing format]