Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Jin, Lei (2453921)

DB_ID Name
3248023 Regulation by TREX1
3249367 STAT6-mediated induction of chemokines
3270619 IRF3-mediated induction of type I IFN
1834941 STING mediated induction of host immune responses
1834949 Cytosolic sensors of pathogen-associated DNA
3134975 Regulation of innate immune responses to cytosolic DNA
3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production

Details on Person Jin, Lei

_displayNameJin, Lei
_timestamp2017-08-22 20:40:00
affiliation[Affiliation:3597628] Albany Medical College, Center for Immunology and Microbial Disease
created[InstanceEdit:2453920] Shamovsky, V, 2012-08-18
modified[InstanceEdit:3597629] Shamovsky, V, 2013-05-21
(author)[InstanceEdit:2453959] Jin, Lei, 2012-08-18
[InstanceEdit:3597627] Jin, Lei, 2013-05-21
[LiteratureReference:2453922] Cellular reactive oxygen species inhibit MPYS induction of IFN?
[LiteratureReference:2453940] MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
[LiteratureReference:2453941] MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP
[LiteratureReference:5218998] Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys˛? methylation by human polycomb repressive complex 2 and vSET
[LiteratureReference:5228606] Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity
[LiteratureReference:5690695] Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling
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