Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Gillespie, Marc E (73681)

DB_ID Name
73887 Death Receptor Signalling
73886 Chromosome Maintenance
75157 FasL/ CD95L signaling
75158 TRAIL signaling
75893 TNF signaling
77285 Beta oxidation of myristoyl-CoA to lauroyl-CoA
77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids
77289 Mitochondrial Fatty Acid Beta-Oxidation
77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
77305 Beta oxidation of palmitoyl-CoA to myristoyl-CoA
77310 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
77346 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
77348 Beta oxidation of octanoyl-CoA to hexanoyl-CoA
77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA
77352 Beta oxidation of butanoyl-CoA to acetyl-CoA
112316 Neuronal System
1187000 Fertilization
159234 Transport of Mature mRNAs Derived from Intronless Transcripts
162587 HIV Life Cycle
162588 Budding and maturation of HIV virion
162658 Golgi Cisternae Pericentriolar Stack Reorganization
162906 HIV Infection
164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
164939 Nef mediated downregulation of CD28 cell surface expression
164940 Nef mediated downregulation of MHC class I complex cell surface expression
164944 Nef and signal transduction
164952 The role of Nef in HIV-1 replication and disease pathogenesis
167590 Nef Mediated CD4 Down-regulation
168253 Host Interactions with Influenza Factors
168256 Immune System
168271 Transport of Ribonucleoproteins into the Host Nucleus
168276 NS1 Mediated Effects on Host Pathways
168277 Influenza Virus Induced Apoptosis
168305 Inhibition of Interferon Synthesis
168315 Inhibition of Host mRNA Processing and RNA Silencing
168888 Inhibition of IFN-beta
168898 Toll-Like Receptors Cascades
169131 Inhibition of PKR
171286 Synthesis and processing of ENV and VPU
174490 Membrane binding and targetting of GAG proteins
174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins
175474 Assembly Of The HIV Virion
5423599 Diseases of Mismatch Repair (MMR)
182218 Nef Mediated CD8 Down-regulation
191859 snRNP Assembly
199977 ER to Golgi Anterograde Transport
199992 trans-Golgi Network Vesicle Budding
204005 COPII (Coat Protein 2) Mediated Vesicle Transport
1300642 Sperm Motility And Taxes
1300645 Acrosome Reaction
1300644 Interaction With The Zona Pellucida
1300652 Sperm:Oocyte Membrane Binding
5545483 Defective Mismatch Repair Associated With MLH1
5632987 Defective Mismatch Repair Associated With PMS2
5632968 Defective Mismatch Repair Associated With MSH6
5632927 Defective Mismatch Repair Associated With MSH3
5632928 Defective Mismatch Repair Associated With MSH2
390522 Striated Muscle Contraction
397014 Muscle contraction
421837 Clathrin derived vesicle budding
1474165 Reproduction
432722 Golgi Associated Vesicle Biogenesis
432720 Lysosome Vesicle Biogenesis
2534343 Interaction With Cumulus Cells
445355 Smooth Muscle Contraction
8934903 Receptor Mediated Mitophagy
556833 Metabolism of lipids
8978868 Fatty acid metabolism
8979227 Triglyceride metabolism
917729 Endosomal Sorting Complex Required For Transport (ESCRT)
5205647 Mitophagy
5205685 Pink/Parkin Mediated Mitophagy

Pathways reviewed by Gillespie, Marc E (73681)

DB_ID Name
69416 Dimerization of procaspase-8
73943 Reversal of alkylation damage by DNA dioxygenases
73942 DNA Damage Reversal
75109 Triglyceride biosynthesis
112122 ALKBH2 mediated reversal of alkylation damage
112126 ALKBH3 mediated reversal of alkylation damage
5357786 TNFR1-induced proapoptotic signaling
5357769 Caspase activation via extrinsic apoptotic signalling pathway
5357905 Regulation of TNFR1 signaling
5357956 TNFR1-induced NFkappaB signaling pathway
140534 Ligand-dependent caspase activation
163560 Triglyceride catabolism
166016 Toll Like Receptor 4 (TLR4) Cascade
166020 Transfer of LPS from LBP carrier to CD14
166054 Activated TLR4 signalling
166058 MyD88:Mal cascade initiated on plasma membrane
166166 MyD88-independent TLR4 cascade
168138 Toll Like Receptor 9 (TLR9) Cascade
168142 Toll Like Receptor 10 (TLR10) Cascade
168176 Toll Like Receptor 5 (TLR5) Cascade
168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
264876 Insulin processing
380994 ATF4 activates genes
381038 XBP1(S) activates chaperone genes
381033 ATF6 (ATF6-alpha) activates chaperones
381042 PERK regulates gene expression
381070 IRE1alpha activates chaperones
381119 Unfolded Protein Response (UPR)
381183 ATF6 (ATF6-alpha) activates chaperone genes
381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
5626978 TNFR1-mediated ceramide production
399997 Acetylcholine regulates insulin secretion
5657655 MGMT-mediated DNA damage reversal
445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
450282 MAPK targets/ Nuclear events mediated by MAP kinases
450294 MAP kinase activation in TLR cascade
450302 activated TAK1 mediates p38 MAPK activation
450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
450341 Activation of the AP-1 family of transcription factors
5694530 Cargo concentration in the ER
8856688 Golgi-to-ER retrograde transport
6807878 COPI-mediated anterograde transport
6811438 Intra-Golgi traffic
6811436 COPI-independent Golgi-to-ER retrograde traffic
6811434 COPI-dependent Golgi-to-ER retrograde traffic
6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
6811440 Retrograde transport at the Trans-Golgi-Network
8953854 Metabolism of RNA
8978868 Fatty acid metabolism
8979227 Triglyceride metabolism
9013973 TICAM1-dependent activation of IRF3/IRF7
9014325 TICAM1,TRAF6-dependent induction of TAK1 complex
1679131 Trafficking and processing of endosomal TLR
1799339 SRP-dependent cotranslational protein targeting to membrane
936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
937039 IRAK1 recruits IKK complex
937042 IRAK2 mediated activation of TAK1 complex
937041 IKK complex recruitment mediated by RIP1
937061 TRIF(TICAM1)-mediated TLR4 signaling
937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex
975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
975155 MyD88 dependent cascade initiated on endosome
975871 MyD88 cascade initiated on plasma membrane
5213460 RIPK1-mediated regulated necrosis
5218900 CASP8 activity is inhibited
5218859 Regulated Necrosis

Details on Person Gillespie, Marc E

_displayNameGillespie, Marc E
_timestamp2017-08-22 20:36:49
affiliation[Affiliation:77249] St. John's University
[Affiliation:158007] Cold Spring Harbor Laboratory
[Affiliation:69324] NYU School of Medicine, Department of Biochemistry
created[InstanceEdit:77412] Gillespie, ME, 2003-10-24 00:00:00
crossReference[DatabaseIdentifier:5357623] ORCID:0000-0002-5766-1702
firstnameMarc E
modified[InstanceEdit:73849] Gillespie, ME, 2003-07-01 00:00:00
[InstanceEdit:75140] D'Eustachio, P, 2003-08-27 11:10:00
[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00
[InstanceEdit:77412] Gillespie, ME, 2003-10-24 00:00:00
[InstanceEdit:140572] Gillespie, ME, 2004-08-24 14:23:15
[InstanceEdit:140575] Gillespie, ME, 2004-08-24 14:48:48
[InstanceEdit:140576] Gillespie, ME, 2004-08-24 14:51:51
[InstanceEdit:180183] D'Eustachio, P, 2006-05-16 19:02:32
[InstanceEdit:5205621] Gillespie, Marc E, 2013-12-04
[InstanceEdit:5357626] Rothfels, Karen, 2014-03-25
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:73680] Gillespie, ME, 0000-00-00 00:00:00
[InstanceEdit:73849] Gillespie, ME, 2003-07-01 00:00:00
[InstanceEdit:73862] Gillespie, ME, 2003-07-03 00:00:00
[InstanceEdit:74972] Gillespie, ME, 2003-07-30 00:00:00
[InstanceEdit:75001] Gillespie, ME, 2003-08-07 00:00:00
[InstanceEdit:75829] Gillespie, ME, 2003-09-02 00:00:00
[InstanceEdit:76038] Gillespie, ME, 2003-09-17 00:00:00
[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00
[InstanceEdit:77412] Gillespie, ME, 2003-10-24 00:00:00
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