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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P02458
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Collagen alpha-1(II) chain alternativeName: Alpha-1 type II collagen component recommendedName: Collagen alpha-1(II) chain /component component recommendedName: Chondrocalcin /component
Links to corresponding entries in other databasesBioGPS Gene:1280
CTD Gene:1280
DOCK Blaster:1U5M
DOCK Blaster:2SEB
ENSEMBL:ENSG00000139219
GeneCards:P02458
KEGG Gene:1280
NCBI Gene:1280
OMIM:108300
OMIM:120140
OMIM:132450
OMIM:151210
OMIM:156550
OMIM:183900
OMIM:184250
OMIM:200610
OMIM:271700
OMIM:604864
OMIM:608805
OMIM:609508
Orphanet:15769
PRO:P02458
Protein Data Bank:1U5M
Protein Data Bank:2SEB
RefSeq:NP_001835
UCSC human:P02458
UniProt:P02458
dbSNP Gene:1280
Other identifiers related to this sequenceCO2A1_HUMAN, A6NGA0, Q12985, Q14009, Q14044, Q14045, Q14046, Q14047, Q14056, Q14058, Q16672, Q1JQ82, Q2V4X7, Q6LBY1, Q6LBY2, Q6LBY3, Q96IT5, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43, CAA26226, M12048, AAA51997, CAA34284, 3452884, 2SEB, L00977, 3452868, Hs.81343.0.S2_3p_at, 3452905, BT007205, CAA34279, 3452890, CAA32030, 3452898, 3452929, 1280, 3452888, MIM:609162, 3452874, AAI16450, M60299_at, X16158, 3452932, 0005130121, MIM:608805, 3452903, 3452911, COL2A1-001, ENSP00000369889, 3452900, 1U5M, 3452866, M60299, AC004801, M25655, MIM:108300, MIM:132450, CAA40330, BC116449, IPR000885, MIM:150600, 11757309_a_at, COL2A1, XP_006719305, 3452919, NP_001835, IPR001007, M32168, 16763783, 7962703, X02372, 3452875, CAA34488, HGNC:2200, MIM:120140, MIM:604864, X02377, 3452910, 37605_at, 3452895, M25730, UPI0000D79713, X02375, 3452889, PH_hs_0024730, 598_at, CAA26223, PF01410, AAC41772, 3452908, CAA34683, MIM:183900, GE57600, CAA34280, 3452904, A_23_P500464, CAA25092, ILMN_1686538, 3452897, X13783, J00116_s_at, 2FSE, 3452887, 217404_s_at, ENSG00000139219, 3452882, 3452891, 3452926, MIM:151210, 3452899, CAA34282, 3452916, XM_006719242, M25656, X00339, 3452931, 3452934, 3452914, CAA34278, X06268_at, 3452892, 3452881, CCDS41778, 1677770, J00116, 3452913, 3452933, BC007252, OTTHUMP00000195063, X16468, AAH07252, AAB60370, 3452941, M25698, CAA26227, CAA29604, CAB002214, ILMN_1742840, IPR008160, 3452870, U15195, MIM:609508, X02373, HPA045939, 3452937, EntrezGene:1280, 3452912, X57010, 3452876, 3452873, 3452928, PF01391, CAA26225, 3452894, 3452883, AAA52038, MIM:156550, 3452940, 3452935, X02371, MIM:271700, 3452902, X06268, 3452927, 3452918, 3452921, X58709, SM00038, SM00214, 3452930, ILMN_1674785, M63281, 3452907, AAA73873, L10347, M25728, 3452872, 3452886, 3452878, AAA52039, 0002260373, uc001rqu.3, 3452864, AAA52051, X16711, IPR002181, 3452867, X02376, PF00093, 3452879, Hs.81343.1.S1_3p_a_at, CAA34283, AAD15287, Hs.408182, X02378, 213492_at, M27468, AAA58428, MIM:184250, CAA26224, 3452909, 3452896, MIM:200610, 3452925, M64345, NM_001844, 85915_at, CAA34281, X02374, AAP35869, OTTHUMP00000195071, ENSP00000338213, NM_033150, uc001rqv.3, UPI0000246C60, NP_149162, CCDS8759, COL2A1-008
Molecules with this sequenceCOL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(26-1487) [endoplasmic reticulum lumen] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(182-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(26-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
COL2A1(182-1487) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
5Hyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GlcGalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-5Hyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-5Hyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-3Hyp-GlcGalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
3x4Hyp-GalHyl-COL2A1(976-1241) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
GlcGalHyl-COL2A1(182-975) [extracellular region] UKENBCdOOOOOOOOOOOOOPGPPURDD
Component ofC-linked procollagen type II trimer [endoplasmic reticulum lumen]
C-linked procollagen type XI trimer [endoplasmic reticulum lumen]
Procollagen type XI [endoplasmic reticulum lumen]
Procollagen type II [endoplasmic reticulum lumen]
Tropocollagen type II [extracellular region]
Tropocollagen type XI [extracellular region]
Procollagen type II [extracellular region]
Procollagen type XI [extracellular region]
Procollagen type XI -N [extracellular region]
Procollagen type II -N [extracellular region]
...
List all 35 items
Represented by generalisation(s)Alpha-1(II) propeptides [endoplasmic reticulum lumen]
Collagen propeptides and chains [endoplasmic reticulum lumen]
Collagen propeptides, chains [endoplasmic reticulum lumen]
4-Hyp collagen propeptides [endoplasmic reticulum lumen]
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen]
5-Hyl collagen propeptides [endoplasmic reticulum lumen]
4-Hyp, 5-Hyl collagen propeptides [endoplasmic reticulum lumen]
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen]
5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen]
4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen]
3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen]
Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen]
4-Hyp Glu-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen]
3,4-Hyp Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen]
Collagen alpha-1(II) chains [extracellular region]
Alpha-1(II) propeptides [extracellular region]
Alpha-1(II) -N propeptides [extracellular region]
Cleaved collagen alpha-1(II) chains [extracellular region]
Collagen type II propeptides [endoplasmic reticulum lumen]
Collagen type XI chains [endoplasmic reticulum lumen]
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen]
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen]
Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen]
Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen]
Collagen propeptides [endoplasmic reticulum lumen]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Extracellular matrix organization

Developmental Biology

Modifications in molecules with this sequence(2S,4R)-4-hydroxyproline at unknown position
(2S,3S)-3-hydroxyproline at unknown position
(2S,5R)-5-hydroxylysine at unknown position
O5-galactosyl-L-hydroxylysine at unknown position
O5-glucosylgalactosyl-L-hydroxylysine at unknown position
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