instancebrowser | sectioned | sidebarwithdynamichierarchy
Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P53779
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Mitogen-activated protein kinase 10 shortName:MAP kinase 10 shortName:MAPK 10 ecNumber2.7.11.24/ecNumber alternativeName: MAP kinase p49 3F12 alternativeName: Stress-activated protein kinase 1b shortName:SAPK1b alternativeName: Stress-activated protein kinase JNK3 alternativeName: c-Jun N-terminal kinase 3
Links to corresponding entries in other databasesBioGPS Gene:5602
Brenda:2.7.11.24
CTD Gene:5602
DOCK Blaster:1JNK
DOCK Blaster:1PMN
DOCK Blaster:1PMQ
DOCK Blaster:1PMU
DOCK Blaster:1PMV
DOCK Blaster:2EXC
EC:2.7.11.24
ENSEMBL:ENSG00000109339
GeneCards:P53779
HapMap:NM_138982
IntEnz:2.7.11.24
KEGG Gene:5602
NCBI Gene:5602
OMIM:602897
Protein Data Bank:1JNK
Protein Data Bank:1PMN
Protein Data Bank:1PMQ
Protein Data Bank:1PMU
Protein Data Bank:1PMV
Protein Data Bank:2EXC
RefSeq:NM_138982
RefSeq:NP_620446
RefSeq:NP_620448
UCSC human:P53779
UniProt:P53779
dbSNP Gene:5602
Other identifiers related to this sequenceMK10_HUMAN, A6NFS3, A6NG28, B3KQ94, Q15707, Q49AP1, ENSG00000109339, ENST00000359221, ENSP00000352157, 1708_at, 1709_g_at, 204813_at, 237413_at, 45430_at, 69092_at, U07620_at, Hs.25209.0.A1_3p_at, g4506080_3p_at, A_14_P128820, A_14_P129258, A_14_P117847, A_23_P45025, CCDS34026, CCDS3612, CCDS3613, GE62730, U07620, U34819, U34820, BC035057, BC051731, EntrezGene:5602, GI_20986507-A, GI_20986505-I, hmm30076-S, GI_20986504-I, GI_20986507-I, ILMN_7405, ILMN_12813, ILMN_14431, IPI00023547, IPI00376687, IPI00795397, IPI00003148, IPI00148567, MIM:602897, OTTHUMP00000161180, OTTHUMP00000161181, OTTHUMP00000161183, OTTHUMP00000161182, OTTHUMT00000253055, OTTHUMT00000253056, OTTHUMT00000253058, OTTHUMT00000253057, 1JNK, 1PMN, 1PMQ, 1PMU, 1PMV, 2EXC, AAC50101, AAC50604, AAC50605, AAH35057, AAH51731, NM_138982, NM_138980, NM_002753, NM_138981, NP_620446, NP_620448, NP_002744, NP_620447, OTTHUMT00000253054, Hs.125503, Hs.598548, P53779, Q499Y8, MK10_HUMAN, Q499Y8_HUMAN, P53779-2, IPR003527, IPR008271, IPR001245, IPR008351, IPR000719
Molecules with this sequencep-T221,Y223-MAPK10 [cytosol] UKENBCdORHGURRPPPPPPDDDDDD
p-T221,Y223-MAPK10 [nucleoplasm] UKENBCdORHGURRPPPPPPDDDDDD
MAPK10 [cytosol] UKENBCdORHGURRPPPPPPDDDDDD
Represented by generalisation(s)p-MAPK8/9/10 [cytosol]
p-MAPK8/9/10 [nucleoplasm]
MAPK8/9/10 [cytosol]
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm]
Processes where molecules and complexes with this sequence are involved

Immune System

TRAF6 Mediated Induction of proinflammatory cytokines

Cellular responses to stress

Modifications in molecules with this sequenceO-phospho-L-threonine at 221
O4'-phospho-L-tyrosine at 223
[Change default viewing format]