instancebrowser | sectioned | sidebarwithdynamichierarchy
Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P53779
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Mitogen-activated protein kinase 10 shortName:MAP kinase 10 shortName:MAPK 10 ecNumber2.7.11.24/ecNumber alternativeName: MAP kinase p49 3F12 alternativeName: Stress-activated protein kinase 1b shortName:SAPK1b alternativeName: Stress-activated protein kinase JNK3 alternativeName: c-Jun N-terminal kinase 3
Links to corresponding entries in other databasesBioGPS Gene:5602
Brenda:2.7.11.24
CTD Gene:5602
DOCK Blaster:1JNK
DOCK Blaster:1PMN
DOCK Blaster:1PMQ
DOCK Blaster:1PMU
DOCK Blaster:1PMV
DOCK Blaster:2EXC
EC:2.7.11.24
ENSEMBL:ENSG00000109339
GeneCards:P53779
HapMap:NM_138982
IntEnz:2.7.11.24
KEGG Gene:5602
NCBI Gene:5602
OMIM:602897
Orphanet:19563
PRO:P53779
Protein Data Bank:1JNK
Protein Data Bank:1PMN
Protein Data Bank:1PMQ
Protein Data Bank:1PMU
Protein Data Bank:1PMV
Protein Data Bank:2EXC
RefSeq:NM_138982
RefSeq:NP_620446
RefSeq:NP_620448
UCSC human:P53779
UniProt:P53779
ZINC_target:P53779
dbSNP Gene:5602
Other identifiers related to this sequenceMK10_HUMAN, A6NFS3, A6NG28, B3KQ94, Q15707, Q49AP1, 3CGF, 2776763, 2776678, U34820, 204813_at, SM00219, 45430_at, 2776687, 2776708, 1PMN, IPR001245, 2776730, CAB022625, 2776675, ILMN_2256907, 3TTI, 69092_at, U07620, 2776723, U07620_at, AC096953, BC065516, 2ZDT, 2776672, 2776689, ENSP00000378598, 2776676, Hs.739136, 3FI3, AC104059, 2776755, IPR008351, 1709_g_at, IPR011009, AK057723, 2EXC, 2776706, 2O2U, D6RC26, UPI00000336D5, 4H39, AC110076, GE62730, A_23_P45025, HGNC:6872, D6RBH2, 3KVX, 11730066_s_at, 2776669, NP_620446, D6RJF9, 2O0U, OTTHUMP00000161179, B3KR72, 2776688, 12436199, EntrezGene:5602, XP_005263193, NM_138980, 2776722, 3V6S, AC108054, 3RTP, XP_006714331, 3OXI, g4506080_3p_at, Hs.125503, MAPK10, AAC50605, A_33_P3254216, EAX05963, 2776671, 2776673, 0004850128, ILMN_2340131, PF07714, 1PMU, SM00220, ILMN_1748281, 2776709, 8101587, 1708_at, 237413_at, BC035057, AAC50604, 2776679, 2OK1, IPR010440, BAG51956, AK091104, D6R9C1, 3OY1, 2B1P, BAG54096, 2776762, 2ZDU, AK124791, 3FI2, U34819, 2WAJ, IPR000719, ENSG00000109339, 3TTJ, 3G9N, MAPK10-001, CH471057, 2776674, BAG52284, 2776707, 3FV8, A8MWW6, 5602, 3G9L, PR01772, 11741019_a_at, 4H3B, AC104827, GE54461, IPR002290, 2776713, AAH35057, 1PMQ, AAH65516, 2776700, 2P33, uc003hpr.3, 1JNK, MIM:602897, Hs.666725, 0000940497, 3G90, 3DA6, 2R9S, Hs.25209.0.A1_3p_at, 3V6R, 3PTG, PF00069, PH_hs_0031094, PF06293, 4H36, AAC50101, 1PMV, CCDS3612, 8654373, IPR020635, OTTHUMP00000218566, CCDS34026, XM_005263130, uc003hps.3, XM_005263129, ENSP00000352157, NM_138982, XP_005263186, MAPK10-012, NP_620448, XP_005263187, XP_006714335, D6RCB1, XP_006714334, D6RFZ7, D6RDG1, D6RFX8, D6RAJ0, UPI0000049042, XP_006714330, D6RAU3, CCDS43247, 2776773, ILMN_1766904, UPI000002AE11, 0004480059, XP_005263192, MAPK10-005, uc003hpt.3, OTTHUMP00000161183, XM_005263135, ENSP00000355297, NP_002744, NM_002753, NM_138981, uc003hpp.3, ILMN_1815780, ENSP00000378589, MAPK10-004, 0001980692, 2776714, CCDS3613, 2776715, NP_620447, OTTHUMP00000161182, UPI00001612A1, 2776759, 2776761, 2776760, 0100780619, OTTHUMP00000161180, uc010ikg.3, MAPK10-002, 2776758, ENSP00000378595, UPI000056F207, XP_005263188, 2776692, MAPK10-201, ENSP00000378590, XM_005263131, XP_006714333, XM_006714269, XP_005263195, XP_006714332, AAH51731, Q499Y8, uc003hpv.3, BC051731
Molecules with this sequencep-T221,Y223-MAPK10 [cytosol] UKENBCdOORHPGPPPPPPURRDDDDDDZ
p-T221,Y223-MAPK10 [nucleoplasm] UKENBCdOORHPGPPPPPPURRDDDDDDZ
MAPK10 [cytosol] UKENBCdOORHPGPPPPPPURRDDDDDDZ
Represented by generalisation(s)p-MAPK8/9/10 [cytosol]
p-MAPK8/9/10 [nucleoplasm]
MAPK8/9/10 [cytosol]
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm]
Processes where molecules and complexes with this sequence are involved

Immune System

TRAF6 Mediated Induction of proinflammatory cytokines

Cellular responses to stress

Modifications in molecules with this sequenceO-phospho-L-threonine at 221
O4'-phospho-L-tyrosine at 223
[Change default viewing format]