Reactome: pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix]

Details

Participates in processes
Name	pyruvate dehydrogenase E2 apoprotein Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex ODP2_HUMAN Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor E2 PDC-E2 70 kDa mitochondrial autoantigen of primary biliary cirrhosis PBC M2 antigen complex 70 kDa subunit
Stable identifier	REACT_4186.1
Links to corresponding entries in other databases	BioGPS Gene:1737 Brenda:2.3.1.12 CTD Gene:1737 DOCK Blaster:1Y8N DOCK Blaster:1Y8O DOCK Blaster:1Y8P EC:2.3.1.12 ENSEMBL:ENSG00000150768 Entrez Gene:1737 HapMap:NM_001931 IntEnz:2.3.1.12 KEGG Gene:1737 OMIM:245348 OMIM:608770 Protein Data Bank:1FYC Protein Data Bank:1Y8N Protein Data Bank:1Y8O Protein Data Bank:1Y8P Protein Data Bank:2DNE RefSeq:NM_001931 RefSeq:NP_001922 UCSC human:P10515 UniProt:P10515 dbSNP Gene:1737
Other identifiers related to this sequence	ODP2_HUMAN, Q16783, Q53EP3, ENSG00000150768, ENST00000280346, ENSP00000280346, 211150_s_at, 213149_at, 212568_s_at, 39041_at, 84706_at, Y00978_at, Hs.115285.1.S1_3p_a_at, g619443_3p_a_at, A_14_P133023, A_24_P281923, A_24_P372672, A_23_P203030, CCDS8354, GE60238, Z48500, AK223596, X13822, BC039084, AF317200, Y00978, J03866, EntrezGene:1737, GI_31711991-S, ILMN_20014, IPI00021338, IPI00604707, IPI00788836, MIM:608770, MIM:245348, OTTHUMP00000165201, OTTHUMT00000258168, 1FYC, 1Y8N, 1Y8O, 1Y8P, 2DNE, CAA88400, BAD97316, CAA32052, AAH39084, AAG31658, CAA68787, AAA62253, NM_001931, NP_001922, OTTHUMT00000258167, Hs.335551, Hs.645882, Q16791, Q53EP3, Q01991, Q86YI5, Q9HAN0, P10515, Q16791_HUMAN, Q53EP3_HUMAN, Q01991_HUMAN, Q86YI5_HUMAN, Q9HAN0_HUMAN, ODP2_HUMAN, IPR001412, IPR003016, IPR000089, IPR001078, IPR004167, IPR000694
Reference entity	UniProt:P10515 DLAT
Cellular compartment	mitochondrial matrix GO
Organism	Homo sapiens
Component of	phosphorylated pyruvate dehydrogenase complex [mitochondrial matrix] pyruvate dehydrogenase complex [mitochondrial matrix] pyruvate dehydrogenase E2 holoenzyme [mitochondrial matrix] pyruvate dehydrogenase E2 trimer [mitochondrial matrix]
Pyruvate metabolism and Citric Acid (TCA) cycle - Pyruvate metabolism - pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ [Homo sapiens] - Regulation of pyruvate dehydrogenase (PDH) complex - PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit [Homo sapiens] - PDP-catalyzed dephosphorylation (activation) of phospho E1 alpha subunit [Homo sapiens]
Entities deduced on the basis of this entity	ENSCAFP00000020671 [mitochondrial matrix] E E [Canis familiaris] Q9TRP7 [mitochondrial matrix] U E E G B C d [Bos taurus] Q95N04 [mitochondrial matrix] U K E [Sus scrofa] ENSSSCP00000015953 [mitochondrial matrix] E E [Sus scrofa] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Sus scrofa] Q8BMF4 [mitochondrial matrix] U K E E G B C d R H R [Mus musculus] P08461 [mitochondrial matrix] U K E E G B C d R H R [Rattus norvegicus] ENSGALP00000012815 [mitochondrial matrix] E E [Gallus gallus] ENSTGUP00000000318 [mitochondrial matrix] E E [Taeniopygia guttata] ENSXETP00000022495 [mitochondrial matrix] E E [Xenopus tropicalis] Q804C3 [mitochondrial matrix] U K E E G G B B C C d d R H R [Danio rerio] B3DIV6 [mitochondrial matrix] U E [Danio rerio] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Danio rerio] B1PH23 [mitochondrial matrix] U E [Drosophila melanogaster] Q7KTK9 [mitochondrial matrix] U E E G B C d F R R [Drosophila melanogaster] Q1WWF8 [mitochondrial matrix] U E E G B C d R R [Drosophila melanogaster] B1PH55 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH28 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH37 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH40 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH15 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH17 [mitochondrial matrix] U E [Drosophila melanogaster] B1PH16 [mitochondrial matrix] U E [Drosophila melanogaster] Q9VM14 [mitochondrial matrix] U K E E G B C d F R R [Drosophila melanogaster] B1PH25 [mitochondrial matrix] U E [Drosophila melanogaster] B1PGZ9 [mitochondrial matrix] U E [Drosophila melanogaster] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Drosophila melanogaster] Q19749 [mitochondrial matrix] U K E W E G B C d R H R [Caenorhabditis elegans] Q8RWN9 [mitochondrial matrix] U K E T [Arabidopsis thaliana] Q5M729 [mitochondrial matrix] U K E T [Arabidopsis thaliana] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Arabidopsis thaliana] A2YKI0 [mitochondrial matrix] U E [Oryza sativa] B8B1M2 [mitochondrial matrix] U E [Oryza sativa] Q7XAL3 [mitochondrial matrix] U K E [Oryza sativa] Q5VS73 [mitochondrial matrix] U E [Oryza sativa] Q6YPG2 [mitochondrial matrix] U K E [Oryza sativa] Q5VS74 [mitochondrial matrix] U K E [Oryza sativa] A3B7K5 [mitochondrial matrix] U E [Oryza sativa] B8AGW7 [mitochondrial matrix] U E [Oryza sativa] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Oryza sativa] P36413 [mitochondrial matrix] U E d [Dictyostelium discoideum] DDB0230192 [mitochondrial matrix] E E d [Dictyostelium discoideum] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Dictyostelium discoideum] P12695 [mitochondrial matrix] U K E S E G B C d R [Saccharomyces cerevisiae] O59816 [mitochondrial matrix] U K E G [Schizosaccharomyces pombe]

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