Reactome: alpha-keto acid dehydrogenase E3 holoenzyme [mitochondrial matrix]

Details

Participates in processes
Name	alpha-keto acid dehydrogenase E3 holoenzyme
Stable identifier	REACT_3390.1
Cellular compartment	mitochondrial matrix GO
Organism	Homo sapiens
Hierarchical view of the components	open all close all show/hide hierarchy types m - known member, m - possible member, c - component
Component of	alpha-keto acid dehydrogenase E3 homodimer [mitochondrial matrix] alpha-ketoglutarate dehydrogenase complex [mitochondrial matrix] branched-chain alpha-ketoacid dehydrogenase complex [mitochondrial matrix] phosphorylated pyruvate dehydrogenase complex [mitochondrial matrix] pyruvate dehydrogenase complex [mitochondrial matrix]
Pyruvate metabolism and Citric Acid (TCA) cycle - Pyruvate metabolism - pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ [Homo sapiens] - Regulation of pyruvate dehydrogenase (PDH) complex - PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit [Homo sapiens] - PDP-catalyzed dephosphorylation (activation) of phospho E1 alpha subunit [Homo sapiens] - Citric acid cycle (TCA cycle) - alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ [Homo sapiens] Metabolism of amino acids and derivatives - Branched-chain amino acid catabolism - a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ [Homo sapiens] - Lysine catabolism - alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ [Homo sapiens]
Entities deduced on the basis of this entity	alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Canis familiaris] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Bos taurus] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Sus scrofa] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Mus musculus] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Rattus norvegicus] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Gallus gallus] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Taeniopygia guttata] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Xenopus tropicalis] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Danio rerio] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Drosophila melanogaster] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Caenorhabditis elegans] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Arabidopsis thaliana] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Oryza sativa] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Dictyostelium discoideum] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Saccharomyces cerevisiae] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Schizosaccharomyces pombe] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [mitochondrial matrix] [Plasmodium falciparum] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [intracellular] [Escherichia coli] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [intracellular] [Mycobacterium tuberculosis] alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens) [intracellular] [Staphylococcus aureus N315]

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