Reactome: alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix]

Details

Participates in processes
Name	alpha-ketoglutarate dehydrogenase E1 apoenzyme 2-oxoglutarate dehydrogenase E1 ODO1_HUMAN 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor Alpha-ketoglutarate dehydrogenase
Stable identifier	REACT_3376.1
Links to corresponding entries in other databases	BioGPS Gene:4967 CTD Gene:4967 ENSEMBL:ENSG00000105953 Entrez Gene:4967 HapMap:NM_001003941 HapMap:NM_002541 OMIM:203740 RefSeq:NM_001003941 RefSeq:NM_002541 RefSeq:NP_001003941 RefSeq:NP_002532 UCSC human:Q02218 UniProt:Q02218 dbSNP Gene:4967
Other identifiers related to this sequence	ODO1_HUMAN, Q9UDX0, ENSG00000105953, ENST00000222673, ENSP00000222673, 201282_at, 1554152_a_at, 40470_at, 78194_at, D10523_at, g4505492_3p_at, A_14_P121386, A_23_P123133, A_24_P9454, A_24_P290770, A_23_P123140, CCDS34627, GE57043, BC009580, AC004859, BC004964, BC014617, D10523, D32064, EntrezGene:4967, GI_4505492-S, ILMN_20815, ILMN_16577, IPI00098902, IPI00386497, MIM:203740, AAH09580, AAQ96884, AAH04964, AAH14617, AAQ96885, BAA01393, BAA06836, NM_002541, NM_001003941, NP_001003941, NP_002532, Hs.488181, Q96DD3, Q9UDX0, Q02218, Q96DD3_HUMAN, Q9UDX0_HUMAN, ODO1_HUMAN, IPR001017, IPR005475
Reference entity	UniProt:Q02218 OGDH
Cellular compartment	mitochondrial matrix GO
Organism	Homo sapiens
Component of	alpha-ketoglutarate dehydrogenase complex [mitochondrial matrix] alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] alpha-ketoglutarate dehydrogenase E1 homodimer [mitochondrial matrix]
Pyruvate metabolism and Citric Acid (TCA) cycle - Citric acid cycle (TCA cycle) - alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ [Homo sapiens] Metabolism of amino acids and derivatives - Lysine catabolism - alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ [Homo sapiens]
Entities deduced on the basis of this entity	ENSCAFP00000004632 [mitochondrial matrix] E E [Canis familiaris] ENSCAFP00000004633 [mitochondrial matrix] E E [Canis familiaris] ENSCAFP00000004619 [mitochondrial matrix] E E [Canis familiaris] ENSCAFP00000004634 [mitochondrial matrix] E E [Canis familiaris] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Canis familiaris] Q148N0 [mitochondrial matrix] U K E E G B C d R H R [Bos taurus] ENSSSCP00000017733 [mitochondrial matrix] E E [Sus scrofa] Q60597 [mitochondrial matrix] U K E E G B C d R H R [Mus musculus] Q5XI78 [mitochondrial matrix] U K E E G B C d R H R [Rattus norvegicus] ENSGALP00000028857 [mitochondrial matrix] E E [Gallus gallus] ENSTGUP00000003463 [mitochondrial matrix] E E [Taeniopygia guttata] ENSXETP00000041195 [mitochondrial matrix] E E [Xenopus tropicalis] ENSXETP00000041196 [mitochondrial matrix] E E [Xenopus tropicalis] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Xenopus tropicalis] Q6PBQ6 [mitochondrial matrix] U E E [Danio rerio] Q58EE8 [mitochondrial matrix] U E E G G B B C C d d [Danio rerio] B8JI08 [mitochondrial matrix] U E [Danio rerio] B8JI07 [mitochondrial matrix] U E [Danio rerio] ENSDARP00000015937 [mitochondrial matrix] E E [Danio rerio] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Danio rerio] Q8IGI6 [mitochondrial matrix] U E E G B C d F R R R R R R [Drosophila melanogaster] C1C538 [mitochondrial matrix] U E [Drosophila melanogaster] Q6NLJ2 [mitochondrial matrix] U E E G B C d R R [Drosophila melanogaster] A8JNU6 [mitochondrial matrix] U K E F [Drosophila melanogaster] Q8IQP9 [mitochondrial matrix] U E E G B C d F R [Drosophila melanogaster] Q95T35 [mitochondrial matrix] U E E G B C d F R R [Drosophila melanogaster] Q0E8J6 [mitochondrial matrix] U K E F [Drosophila melanogaster] Q8IQQ0 [mitochondrial matrix] U E E G B C d F R [Drosophila melanogaster] Q9VVC5 [mitochondrial matrix] U E E G B C d F R R R R R [Drosophila melanogaster] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Drosophila melanogaster] O61199 [mitochondrial matrix] U K E W E G B C d R H R [Caenorhabditis elegans] O49541 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q9M2T8 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q84VW8 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q9ZRQ2 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q9FLH2 [mitochondrial matrix] U K E T [Arabidopsis thaliana] Q0WME3 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q0WLT5 [mitochondrial matrix] U E T [Arabidopsis thaliana] Q56WF9 [mitochondrial matrix] U E T [Arabidopsis thaliana] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Arabidopsis thaliana] Q01LD8 [mitochondrial matrix] U E [Oryza sativa] B8AT82 [mitochondrial matrix] U E [Oryza sativa] Q6Z3X5 [mitochondrial matrix] U K E [Oryza sativa] Q0JDN5 [mitochondrial matrix] U K E [Oryza sativa] Homologues of alpha-ketoglutarate dehydrogenase E1 apoenzyme [mitochondrial matrix] [Oryza sativa] Q54JE4 [mitochondrial matrix] U E d [Dictyostelium discoideum] P20967 [mitochondrial matrix] U K E S E G B C d R [Saccharomyces cerevisiae] O74378 [mitochondrial matrix] U K E G [Schizosaccharomyces pombe] Q8I6S5 [mitochondrial matrix] U K E P [Plasmodium falciparum] P0AFG3 [intracellular] U K K E [Escherichia coli] O50463 [intracellular] U K K E [Mycobacterium tuberculosis] Q99U74 [intracellular] U K E [Staphylococcus aureus N315]

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