Reactome: pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix]

Details

Participates in processes
Name	pyruvate dehydrogenase complex X component (E3 binding protein) ODPX_HUMAN Pyruvate dehydrogenase protein X component, mitochondrial precursor Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex E3-binding protein E3BP proX
Stable identifier	REACT_3077.1
Links to corresponding entries in other databases	BioGPS Gene:8050 CTD Gene:8050 ENSEMBL:ENSG00000110435 Entrez Gene:8050 HapMap:NM_003477 KEGG Gene:8050 OMIM:245349 OMIM:608769 Protein Data Bank:1ZY8 Protein Data Bank:2DNC Protein Data Bank:2F5Z Protein Data Bank:2F60 RefSeq:NM_003477 RefSeq:NP_003468 UCSC human:O00330 UniProt:O00330 dbSNP Gene:8050
Other identifiers related to this sequence	ODPX_HUMAN, O60221, Q96FV8, Q99783, ENSG00000110435, ENST00000227868, ENSP00000227868, 203067_at, 36164_at, U79296_at, g4505698_3p_at, A_14_P201582, A_14_P130607, A_23_P36266, A_32_P174043, CCDS7896, GE81284, AF001437, Y13145, U82328, AJ298105, BC010389, U79296, EntrezGene:8050, GI_4505698-S, ILMN_30028, IPI00298423, MIM:608769, MIM:245349, 1ZY8, 2F5Z, 2DNC, 2F60, AAB66315, CAA73606, AAC39661, CAC18649, AAH10389, AAB50223, NM_003477, NP_003468, Hs.653365, O00330, ODPX_HUMAN, IPR003016, IPR000089, IPR001078, IPR004167
Reference entity	UniProt:O00330 PDHX
Cellular compartment	mitochondrial matrix GO
Organism	Homo sapiens
Component of	phosphorylated pyruvate dehydrogenase complex [mitochondrial matrix] pyruvate dehydrogenase complex [mitochondrial matrix]
Pyruvate metabolism and Citric Acid (TCA) cycle - Pyruvate metabolism - pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ [Homo sapiens] - Regulation of pyruvate dehydrogenase (PDH) complex - PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit [Homo sapiens] - PDP-catalyzed dephosphorylation (activation) of phospho E1 alpha subunit [Homo sapiens]
References
Brown, RM, Head, RA, Brown, GK Pyruvate dehydrogenase E3 binding protein deficiency. 2002 Hum Genet PubMed Harris, RA, Bowker-Kinley, MM, Wu, P, Jeng, J, Popov, KM Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex. 1997 J Biol Chem PubMed
Entities deduced on the basis of this entity	ENSCAFP00000010269 [mitochondrial matrix] E E [Canis familiaris] P22439 [mitochondrial matrix] U K E [Bos taurus] ENSSSCP00000014131 [mitochondrial matrix] E E [Sus scrofa] Q8BKZ9 [mitochondrial matrix] U K E E G G B B C C d d R H R [Mus musculus] Q5BJX2 [mitochondrial matrix] U E E [Rattus norvegicus] Q7TQ85 [mitochondrial matrix] U K E E G B C d R H R [Rattus norvegicus] Homologues of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Rattus norvegicus] Q5F3G9 [mitochondrial matrix] U K E [Gallus gallus] ENSTGUP00000010399 [mitochondrial matrix] E E [Taeniopygia guttata] ENSXETP00000016458 [mitochondrial matrix] E E [Xenopus tropicalis] A8E5K3 [mitochondrial matrix] U E [Danio rerio] Q6PHF5 [mitochondrial matrix] U K E [Danio rerio] Q6NW45 [mitochondrial matrix] U E [Danio rerio] Homologues of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Danio rerio] Ghost homologue of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Drosophila melanogaster] O45279 [mitochondrial matrix] U K E W E G B C d R H R [Caenorhabditis elegans] Q0WQF7 [mitochondrial matrix] U K E T [Arabidopsis thaliana] B8B2U7 [mitochondrial matrix] U E [Oryza sativa] Q654L9 [mitochondrial matrix] U K E [Oryza sativa] B9FTG2 [mitochondrial matrix] U E [Oryza sativa] Q42979 [mitochondrial matrix] U E [Oryza sativa] Homologues of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Oryza sativa] P36413 [mitochondrial matrix] U E d [Dictyostelium discoideum] DDB0230192 [mitochondrial matrix] E E d [Dictyostelium discoideum] Homologues of pyruvate dehydrogenase E2 apoprotein [mitochondrial matrix] [Dictyostelium discoideum] Ghost homologue of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Saccharomyces cerevisiae] Ghost homologue of pyruvate dehydrogenase complex X component (E3 binding protein) [mitochondrial matrix] [Schizosaccharomyces pombe]

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