Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Homo sapiens]
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Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
Stable identifier
REACT_714.3
Authored
D'Eustachio, P
, 2004-01-13
Reviewed
He, L
, 2010-05-10
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The plasma membrane-associated protein SLC28A1 mediates the transport of one molecule of 2'-deoxyadenosine, adenosine, cytidine, thymidine, or uridine, and one sodium ion, from the extracellular space to the cytosol. [
Ritzel
et al
1997
]
Input (present at start of reaction)
ligands of SLC28A1 [extracellular region]
sodium ion [extracellular region]
C
C
P
Output (present at end of reaction)
ligands of SLC28A1 [cytosol]
sodium ion [cytosol]
C
C
P
Catalyst
SLC28A1 [plasma membrane]
U
K
E
G
B
C
d
O
R
H
U
R
GO molecular function
nucleoside:sodium symporter activity
GO
Organism
Homo sapiens
Cellular compartment
plasma membrane
GO
References
Ritzel, MW
,
Yao, SY
,
Huang, MY
,
Elliott, JF
,
Cass, CE
,
Young, JD
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)
1997
Am J Physiol Cell Physiol
PubMed
Equivalent event(s) in other organism(s)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Canis familiaris]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Bos taurus]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Sus scrofa]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Mus musculus]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Rattus norvegicus]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Gallus gallus]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Taeniopygia guttata]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Xenopus tropicalis]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Danio rerio]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Drosophila melanogaster]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Caenorhabditis elegans]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Escherichia coli]
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 [Staphylococcus aureus N315]
Participating molecules
2'-deoxyadenosine [cytosol]
C
C
P
2'-deoxyadenosine [extracellular region]
C
C
P
adenosine [cytosol]
C
C
P
Adenosine [extracellular region]
C
C
P
cytidine [cytosol]
C
C
P
cytidine [extracellular region]
C
C
P
ligands of SLC28A1 [cytosol]
ligands of SLC28A1 [extracellular region]
SLC28A1 [plasma membrane]
U
K
E
G
B
C
d
O
R
H
U
R
sodium ion [cytosol]
C
C
P
...
List all 15 participating molecules
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ChEBI identifiers
KEGG COMPOUND identifiers
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Date: 2010-09-02 22:13:04
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